Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carlos J. Duque-Afonso"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Cochlear implant spectral resolution is limited by current spread from each stimulation electrode. Here the authors compare optogenetic, electric and acoustic stimulation in gerbils and demonstrate improved spectral resolution of optogenetic over con
Externí odkaz:
https://doaj.org/article/6ae2cefcee224fd0b358800d836f009d
Autor:
Vladan Rankovic, Christian Vogl, Nele M. Dörje, Iman Bahader, Carlos J. Duque-Afonso, Anupriya Thirumalai, Thomas Weber, Kathrin Kusch, Nicola Strenzke, Tobias Moser
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Hearing impairment is the most common sensory disorder in humans. So far, rehabilitation of profoundly deaf subjects relies on direct stimulation of the auditory nerve through cochlear implants. However, in some forms of genetic hearing impairment, t
Externí odkaz:
https://doaj.org/article/d677970f343344dd93d8b9c6c85a6184
Autor:
Mihai Alevra, Sebastian Strauss, Carlos J. Duque-Afonso, Ralf Jungmann, Felipe Opazo, Shama Sograte-Idrissi, Tobias Moser, Silvio O. Rizzoli, Thomas Schlichthaerle
Publikováno v:
Nanoscale
A standard procedure to study cellular elements is via immunostaining followed by optical imaging. This methodology typically requires target-specific primary antibodies (1.Abs), which are revealed by secondary antibodies (2.Abs). Unfortunately, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a5456ae9453b81fcec62fba561b52
https://doi.org/10.1039/d0nr00227e
https://doi.org/10.1039/d0nr00227e
Autor:
Alexander C. Meyer, Christian Vogl, Mareike Töpperwien, Tobias Moser, Carlos J. Duque-Afonso, Daniel Keppeler, Tim Salditt, Tabea Quilitz, Christoph A. Kampshoff, Roland Hessler, Jannis Schaeper, Anupriya Thirumalai
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the USA
Proceedings of the National Academy of Sciences of the USA
The cochlea of our auditory system is an intricate structure deeply embedded in the temporal bone. Compared with other sensory organs such as the eye, the cochlea has remained poorly accessible for investigation, for example, by imaging. This limitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcbe0307ea507caf1723ae383ffbc8a
https://doi.org/10.1073/pnas.2014472118
https://doi.org/10.1073/pnas.2014472118
Autor:
Sebastian Strauss, Mihai Alevra, Carlos J. Duque-Afonso, Felipe Opazo, Thomas Schlichthaerle, Shama Sograte-Idrissi, Tobias Moser, Ralf Jungmann, Silvio O. Rizzoli
Publikováno v:
Nanoscale
Correction for ‘Circumvention of common labelling artefacts using secondary nanobodies’ by Shama Sograte-Idrissi et al., Nanoscale, 2020, 12, 10226–10239, DOI: 10.1039/D0NR00227E.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c1da5cb0f37f5f0cb17efa58e40003
https://hdl.handle.net/21.11116/0000-0007-D56E-E21.11116/0000-0007-D570-A
https://hdl.handle.net/21.11116/0000-0007-D56E-E21.11116/0000-0007-D570-A
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Cochlear implants (CIs) electrically stimulate spiral ganglion neurons (SGNs) and partially restore hearing to half a million CI users. However, wide current spread from intracochlear electrodes limits spatial selectivity (i.e. spectral resolution) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78faaecf9b7d70d545830f28b85aee7e
https://hdl.handle.net/21.11116/0000-000A-D15D-221.11116/0000-000A-D15F-0
https://hdl.handle.net/21.11116/0000-000A-D15D-221.11116/0000-000A-D15F-0
Autor:
Christian Vogl, Antoine Huet, Christian Wrobel, Marcus Jeschke, Carlos J. Duque-Afonso, Alexander Dieter, Daniel Keppeler, Gerhard Hoch, Tobias Moser
Publikováno v:
Science Translational Medicine
Cochlear implants partially restore hearing via direct electrical stimulation of spiral ganglion neurons (SGNs). However, spread of excitation from each electrode limits spectral coding. We explored the use of optogenetics to deliver spatially restri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ac2908613540d894692ffbfac08e17
https://doi.org/10.1126/scitranslmed.aao0540
https://doi.org/10.1126/scitranslmed.aao0540
Autor:
SangYong Jung, Zhizi Jing, Anja Scharinger, Maria Magdalena Picher, Carlos J. Duque-Afonso, Tobias Moser, Gerhard Hoch, Tzu-Lun Ohn, Nicola Strenzke, Mark A. Rutherford
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
For sounds of a given frequency, spiral ganglion neurons (SGNs) with different thresholds and dynamic ranges collectively encode the wide range of audible sound pressures. Heterogeneity of synapses between inner hair cells (IHCs) and SGNs is an attra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5702e2cbfac9b91d75e2ea6947dd96e4
https://hdl.handle.net/11858/00-001M-0000-002C-6771-E11858/00-001M-0000-002C-6772-C11858/00-001M-0000-002B-14AB-D
https://hdl.handle.net/11858/00-001M-0000-002C-6771-E11858/00-001M-0000-002C-6772-C11858/00-001M-0000-002B-14AB-D