Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Carlos J. Carrera"'
Autor:
Trisha Suppes, Shabnam I. Thompson, William G. Anderson, Carlos J. Carrera, Muhammed Aslam, Sanjai D. Rao, Julia E. Vertrees, David Lawrence, Mitchell S. Finkel, Timothy M. Juergens, Sidney Zisook, James Wilcox, Joseph Westermeyer, Paul B. Hicks, John Kasckow, Gerardo Villarreal, Sriram Ramaswamy, Ilanit Tal, Clifford S. Nasdahl, Kari A. Jones, Gihyun Yoon, David Loreck, Steven Lieske, K. Ryan Connolly, Somaia Mohamed, James P. Michalets, Gauri Khatkhate, Nicholas Rosenlicht, Patricia Pilkinton, Mamta Sapra, Gary R. Johnson, Michael E Thase, Gunnar Larson, Lori L. Davis, Mary Klatt, Jean Yoon, Thomas P. Beresford, Cristobal A. Nogues, Grant D. Huang, Aimee R. Mayeda, Peijun Chen, Lawrence J. Albers, Julia L. Winston, John T. Little, Solomon S. Williams, Bernard A. Fischer, George Jurjus, Andre Tapp, Ronald Fernando, Beata Planeta, Joseph M. LaMotte, Theresa Gleason, Ali Iranmanesh, D. Cyril D’Souza, Keith D. Anderson, Alexander B. Niculescu, Ayman Fareed, Alexandra Scrymgeour, Sheetal Marri, Kimberly R. Weingart, Robin A. Hurley
Publikováno v:
JAMA. 318(2)
Importance Less than one-third of patients with major depressive disorder (MDD) achieve remission with their first antidepressant. Objective To determine the relative effectiveness and safety of 3 common alternate treatments for MDD. Design, Setting,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896011da653c68a8d53f5a2dc9d96e6d
https://pubmed.ncbi.nlm.nih.gov/28697241
https://pubmed.ncbi.nlm.nih.gov/28697241
Autor:
Patricia Morin, Ernest Beutler, Alan Saven, Carlos J. Carrera, Andrea C. Kay, Robert McMillan, Dennis A. Carson, Lawrence D. Piro, Robert L. Longmire
Publikováno v:
Leukemialymphoma. 5(1)
Hereditary adenosine deaminase deficiency results in failure of the lymphocyte development. This occurs because of the accumulation of deoxyadenine nucleotides in cells with high deoxycytidine kinase and low 5'-nucleotidase activity. 2-Chlorodeoxyade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290d0849212f460fb3a60c336d580245
https://pubmed.ncbi.nlm.nih.gov/27463204
https://pubmed.ncbi.nlm.nih.gov/27463204
Publikováno v:
Leukemialymphoma. 5
Ninety patients with advanced refractory chronic lymphocytic leukemia (CLL) were treated with 2-chlorodeoxyadenosine (2-CdA) administered either as a 0.1 mg/kg/day 7-day continuous intravenous infusion or as a 0.028 mg to 0.14 mg/kg/day 2-hour bolus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479ee349d3c0e7ad54fa97b048fbf6f0
https://pubmed.ncbi.nlm.nih.gov/27463495
https://pubmed.ncbi.nlm.nih.gov/27463495
Autor:
Alice L. Yu, Ayse Batova, John Yu, Howard B. Cottam, Mitchell B. Diccianni, Carlos J. Carrera
Publikováno v:
Blood. 107:898-903
The deficiency of methylthioadenosine phosphorylase (MTAP) in T-cell acute lymphoblastic leukemia (T-ALL) and other cancers, while constitutively expressed in normal cells, allows for selective therapy using L-alanosine, an inhibitor of de novo AMP s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e32a8b0d8348ac70c702ccddcea313
https://doi.org/10.1182/blood-2005-06-2430
https://doi.org/10.1182/blood-2005-06-2430
Autor:
Henry S. Friedman, Mathias Schmid, Michael Rosenbach, Carlos J. Carrera, Dennis A. Carson, Malini Sen
Publikováno v:
Oncogene. 19:5747-5754
Homozygous deletions of human chromosome 9p21 occur frequently in malignant cell lines, and are also common in primary gliomas, lung cancers, and leukemias. Moving from the centromere to the telomere, this complex region encodes the tumor suppressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52da573e60e1d4954579a561f01dd5b
https://doi.org/10.1038/sj.onc.1203942
https://doi.org/10.1038/sj.onc.1203942
Autor:
David W. Rose, Carlos J. Carrera, Souichi Adachi, Dennis A. Carson, Qi Chao, Lorenzo M. Leoni, Davide Genini, Howard B. Cottam
Publikováno v:
Blood. 96:3537-3543
Adenine deoxynucleosides induce apoptosis in quiescent lymphocytes and are thus useful drugs for the treatment of indolent lymphoproliferative diseases. To explain why deoxyadenosine and its analogs are toxic to a cell that is not undergoing replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15261a679b124eb24013dccda2e8d1df
https://doi.org/10.1182/blood.v96.10.3537.h8003537_3537_3543
https://doi.org/10.1182/blood.v96.10.3537.h8003537_3537_3543
Autor:
Howard B. Cottam, Dennis A. Carson, Ernest Hamel, Hsiencheng Shih, Lorenzo M. Leoni, Davide Genini, Carlos J. Carrera
Publikováno v:
JNCI: Journal of the National Cancer Institute. 92:217-224
Background Certain antimitotic drugs have antitumor activities that apparently result from interactions with nontubulin components involved in cell growth and/or apoptotic cell death. Indanocine is a synthetic indanone that has been identified by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9990e064642851d88fb17c6d98b75b36
https://doi.org/10.1093/jnci/92.3.217
https://doi.org/10.1093/jnci/92.3.217
Publikováno v:
Brazilian Journal of Oceanography, Vol 26, Iss 1, Pp 51-130 (1977)
1 - La hidrología del área estudiada, entre las latitudes 29º y 34ºS, es muy compleja y esta influenciada por aguas tropicales traídas por la Corriente de Brasil, por aguas subantarticas traídas por la Corriente de las Malvinas, por las aguas d
Externí odkaz:
https://doaj.org/article/03b8e6e333ac4493afdca8eeac9806be
Autor:
Tsutomu Nobori, Carlos J. Carrera, Denise M. Malicki, Dennis A. Carson, Mathias Schmid, Katari Campbell, Michael Rosenbach
Publikováno v:
Oncogene. 17:2669-2675
Homozygous deletions of the tumor suppressor gene p16INK4A and deficiency of methylthioadenosine phosphorylase (MTAP), both located on chromosome 9p21, have been independently reported in non-small cell lung cancer (NSCLC). To determine the frequency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2950934aef5ae393776dc879bd80ddc
https://doi.org/10.1038/sj.onc.1202205
https://doi.org/10.1038/sj.onc.1202205
Autor:
Davide Genini, Michael Rosenbach, Dennis A. Carson, Howard B. Cottam, Lorenzo M. Leoni, Qi Chao, Imawati Budihardjo, Xiaodong Wang, Carlos J. Carrera
Publikováno v:
Proceedings of the National Academy of Sciences. 95:9567-9571
Adenine deoxynucleosides, such as 2-chloro-2′-deoxyadenosine (2CdA) induce apoptosis in quiescent lymphocytes, and are thus useful drugs for the treatment of indolent lymphoproliferative diseases. However, it has remained puzzling why deoxyadenosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfb5ad06bf3de2c132827e52a775fb4
https://doi.org/10.1073/pnas.95.16.9567
https://doi.org/10.1073/pnas.95.16.9567