Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carlos H.R. Boasquevisque"'
Autor:
G. Alexander Patterson, Ronald K. Scheule, Jon M. Ritter, Lihui Qin, Mariano Boglione, Jonathan S. Bromberg, Carlos H.R. Boasquevisque, Lisa A. DeBruyne, Nelson S. Yew, Bassem N. Mora
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 119:913-920
Background: The aim of the current work was to study the feasibility of functional gene transfer using the gene encoding for transforming growth factor–β1, a known immunosuppressive cytokine, on rat lung allograft function in the setting of acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad85ab0aeb41976c78514e656ed8725
https://doi.org/10.1016/s0022-5223(00)70086-9
https://doi.org/10.1016/s0022-5223(00)70086-9
Autor:
G. Alexander Patterson, Carlos H.R. Boasquevisque, Itaru Nagahiro, Masafumi Hiratsuka, Joel D. Cooper, Tyler White, Motoki Yano
Publikováno v:
The Annals of Thoracic Surgery. 66:351-355
Recombinant Kunitz protease inhibitor (rKPI-BG022) is more homologous to human Kunitz protease inhibitor than is aprotinin. Because aprotinin has been reported to inhibit free radicals, we hypothesized that rKPI would ameliorate reperfusion injury ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293fd0d69136e5d224b5c3aa938a0be3
https://doi.org/10.1016/s0003-4975(98)00531-1
https://doi.org/10.1016/s0003-4975(98)00531-1
Autor:
G. Alexander Patterson, Ronald K. Scheule, Jennifer B. Nietupski, William O. Osburn, Carlos H.R. Boasquevisque, Joel D. Cooper, Matthew Bernstein, Bassem N. Mora, M D Botney
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 115:38-44
Objective: Gene therapy is a promising strategy to modify ischemia-reperfusion injury and rejection after transplantation. We evaluated variables that may affect ex vivo gene transfer to rat lung isografts. Methods: Left lungs were harvested and perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850bcb08fc43143db039f25e03abe7c
https://doi.org/10.1016/s0022-5223(98)70440-4
https://doi.org/10.1016/s0022-5223(98)70440-4
Autor:
William O. Osburn, Wei Zhang, Bassem N. Mora, David Peterson, G. Alexander Patterson, Teng C. Lee, Joel D. Cooper, Ronald K. Scheule, Jennifer B. Nietupski, Carlos H.R. Boasquevisque, M D Botney, Matthew Bernstein
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 114(5):783-792
Objectives: Our objectives were to determine the feasibility, efficacy, and safety of in vivo and ex vivo liposome-mediated gene transfer to lung isografts. Methods: Fischer rats were divided into three main groups: (1) Nontransplant setting: Liposom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98249b530a4562eac31ad3d233f1ecb
Autor:
G. Alexander Patterson, Ronald K. Scheule, Joel D. Cooper, Carlos H.R. Boasquevisque, M D Botney, Motoki Yano
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 114:793-802
Objective: Gene transfer to lung grafts may be useful in ameliorating ischemia-reperfusion injury and rejection. Efficient gene transfection to the whole organ may prove problematic. Proximal pulmonary artery endothelial transfection might provide be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc73e9c3cc41d9488bfa03d7637a71b
https://doi.org/10.1016/s0022-5223(97)70083-7
https://doi.org/10.1016/s0022-5223(97)70083-7
Autor:
Itaru Nagahiro, G. Alexander Patterson, Ralph A. Schmid, Bassem N. Mora, Teng C. Lee, Joel D. Cooper, Carlos H.R. Boasquevisque
Publikováno v:
The Annals of Thoracic Surgery. 63:1556-1560
Background. Although whole-organ gene transfer has been reported in heart and liver transplant models, it has not been well characterized in lung grafts. The aim of this study was to determine the feasibility of ex vivo gene transfer to rat lung isog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedd25d59f6abae933d47a4e0d436e50
https://doi.org/10.1016/s0003-4975(97)00237-3
https://doi.org/10.1016/s0003-4975(97)00237-3
Autor:
Itaru Nagahiro, G. Alexander Patterson, Carlos H.R. Boasquevisque, Shozo Fujino, Joel D. Cooper, Anastasios N. Triantafillou, Motoki Yano
Publikováno v:
The Annals of Thoracic Surgery. 63:1383-1389
Inhalation of nitric oxide (NO) has been shown to have beneficial effects on a variety of acute lung injuries, including lung allograft reperfusion injury. The purpose of the present study was to investigate the effects of inhaled NO at the time of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5334199cd7be0a7d22fa8a86272720c
https://doi.org/10.1016/s0003-4975(97)00236-1
https://doi.org/10.1016/s0003-4975(97)00236-1
Autor:
Michael J. Welch, Timothy J. McCarthy, Mariano Boglione, Bassem N. Mora, Geoffrey L. Uy, G. Alexander Patterson, Carlos H.R. Boasquevisque
Publikováno v:
The Annals of thoracic surgery. 69(1)
Increased nitric oxide production accompanies acute lung allograft rejection. Transforming growth factor-beta1 is an immunosuppressive cytokine capable of ameliorating acute rejection. The purpose of this study was to determine whether exhaled nitric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcdc228636c4881974eab1d5076d329
https://pubmed.ncbi.nlm.nih.gov/10654515
https://pubmed.ncbi.nlm.nih.gov/10654515
Autor:
Carlos H.R. Boasquevisque, Richard Lee, Joel D. Cooper, Mariano Boglione, Masafumi Hiratsuka, G. Alexander Patterson, Ronald K. Scheule
Publikováno v:
The Annals of thoracic surgery. 66(3)
Background. Gene therapy is a promising strategy for the treatment of inoperable pulmonary tumors and rejection after lung transplantation. However, unlike ex vivo administration, intravenous in vivo transfection lacks organ specificity and has a lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc16fab2b7db5d61d18d975d8082eb6
https://pubmed.ncbi.nlm.nih.gov/9768949
https://pubmed.ncbi.nlm.nih.gov/9768949
Autor:
Carlos H.R. Boasquevisque, Alan L. Schwartz, Ralph A. Schmid, Ando K, Joel D. Cooper, Masaaki Narita, G.A. Patterson, Botney
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 11(6)
Objective: New methods to introduce genetic material into cells in vivo may revolutionize current treatment modalities. Expression of functional genes in lung allografts could be used as a prophylactic strategy for reperfusion injury and rejection. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cd0fd7eb7a65ddb2616abf33f96a47
https://pubmed.ncbi.nlm.nih.gov/9237582
https://pubmed.ncbi.nlm.nih.gov/9237582