Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carlos H.M. Rodrigues"'
Autor:
Malancha Karmakar, Vittoria Cicaloni, Carlos H.M. Rodrigues, Ottavia Spiga, Annalisa Santucci, David B. Ascher
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 271-277 (2022)
Alkaptonuria (AKU), a rare genetic disorder, is characterized by the accumulation of homogentisic acid (HGA) in the body. Affected individuals lack functional levels of an enzyme required to breakdown HGA. Mutations in the homogentisate 1,2-dioxygena
Externí odkaz:
https://doaj.org/article/09d4b2fbbc3e4c9c8c87bcee86a8dfe2
Autor:
Yunzhuo Zhou, Stephanie Portelli, Megan Pat, Carlos H.M. Rodrigues, Thanh-Binh Nguyen, Douglas E.V. Pires, David B. Ascher
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5381-5391 (2021)
Kinases play crucial roles in cellular signalling and biological processes with their dysregulation associated with diseases, including cancers. Kinase inhibitors, most notably those targeting ABeLson 1 (ABL1) kinase in chronic myeloid leukemia, have
Externí odkaz:
https://doaj.org/article/65c1508535fd4770a282035f97f77587
Autor:
Sundeep Chaitanya Vedithi, Carlos H.M. Rodrigues, Stephanie Portelli, Marcin J. Skwark, Madhusmita Das, David B. Ascher, Tom L. Blundell, Sony Malhotra
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 271-286 (2020)
Rifampin resistance in leprosy may remain undetected due to the lack of rapid and effective diagnostic tools. A quick and reliable method is essential to determine the impacts of emerging detrimental mutations in the drug targets. The functional cons
Externí odkaz:
https://doaj.org/article/8ccf97acfc614fb2aff96eaf6bc513fb
Autor:
Walter P. Abhayaratna, E. Potter, Thomas H. Marwick, Carlos H.M. Rodrigues, Partho P. Sengupta, David B. Ascher
Publikováno v:
JACC: Cardiovascular Imaging. 14:1904-1915
Objectives The purpose of this study was to identify whether machine learning from processing of continuous wave transforms (CWTs) to provide an “energy waveform” electrocardiogram (ewECG) could be integrated with echocardiographic assessment of