Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carlos H V Nascimento Filho"'
Autor:
Carlos H. V. Nascimento-Filho, Ericka J. D. Silveira, Eny M. Goloni-Bertollo, Lelia Batista de Souza, Cristiane H. Squarize, Rogerio M. Castilho
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background The skin is the largest organ of the human body. Upon injury, the skin triggers a sequence of signaling pathways that induce epithelial proliferation, migration, and ultimately, the re-establishment of the epithelial barrier. Our
Externí odkaz:
https://doaj.org/article/4ba4600238e2414e99cf61a0e67f99cc
Autor:
Carlos H. V. Nascimento-Filho, Alexandra T. Glinos, Yeejin Jang, Eny M. Goloni-Bertollo, Rogerio M. Castilho, Cristiane H. Squarize
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5633 (2022)
The human body is endowed with an extraordinary ability to maintain different oxygen levels in various tissues and organs. The maintenance of physiological levels of oxygen is known as physoxia. The development of hypoxic conditions plays an importan
Externí odkaz:
https://doaj.org/article/c3b338a60bba46b2a4d9adfdf6a57204
Autor:
Mingqi Zhou, Cassandra Van, Jeffrey Molendijk, Ivan Yao-Yi Chang, Casey Johnson, Leandro M. Velez, Reichelle X. Yeo, Hosung Bae, Johnny Le, Natalie Larson, Ron Pulido, Carlos H V Nascimento-Filho, Andrea Hevener, Lauren M. Sparks, Jaime N. Justice, Erin E. Kershaw, Ivan Marazzi, Nicholas Pannunzio, Dequina Nicholas, Benjamin Parker, Cholsoon Jang, Selma Masri, Marcus Seldin
/IntroductionInter-organ communication is a vital process to maintain physiologic homeostasis, and its dysregulation contributes to many human diseases. Beginning with the discovery of insulin over a century ago, characterization of molecules respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c627cd847be25fc88c25f9732bceb22
https://doi.org/10.1101/2023.05.10.540142
https://doi.org/10.1101/2023.05.10.540142
Autor:
Ericka J. D. Silveira, Carlos H. V. Nascimento Filho, Veronica Q. Yujra, Liana P. Webber, Rogerio M. Castilho, Cristiane H. Squarize
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 901 (2020)
The circadian rhythm regulates the physiology and behavior of living organisms in a time-dependent manner. Clock genes have distinct roles including the control over gene expression mediated by the transcriptional activators CLOCK and BMAL1, and the
Externí odkaz:
https://doaj.org/article/efdf6e4648f34cf597dc14d29d33fcdd
Autor:
Cristiane H. Squarize, Rogerio M. Castilho, Eliete Neves Silva Guerra, Carlos H V Nascimento Filho, Thamara M Marinho Bezerra, Ana Elizia Mascarenhas Marques
Publikováno v:
Journal of Oral Pathology & Medicine. 49:771-779
Introduction Alterations of the epigenome may influence cancer initiation and progression. At the cellular level, histones are key regulators of chromatin accessibility and gene transcription; thus, the inhibition of histone deacetylase enzymes (HDAC
Autor:
Cristiane H. Squarize, L. Webber, Carlos H. V. Nascimento-Filho, Eny Maria Goloni-Bertollo, Rogerio M. Castilho, Gabriell B. Borgato
Publikováno v:
FASEB J
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide and is characterized by a fast-paced growth. Like other solid tumors, the HNSCC growth rate results in the development of hypoxic regions identified by the ex
Autor:
Cristiane H. Squarize, Liana Preto Webber, Brian Yip, Rogerio M. Castilho, Carlos H V Nascimento Filho, Ha B. Park
Publikováno v:
J Dermatol Sci
Autor:
Pengda Liu, Antonio L. Amelio, Rogerio M. Castilho, Zhichuan Zhu, Adele M. Musicant, Chloe Twomey, Jason Tasoulas, Kshitij Parag-Sharma, Carlos H. V. Nascimento-Filho
Publikováno v:
Oral Oncol
Objectives Mucoepidermoid carcinoma (MEC) is the most common type of salivary gland malignancy. Advanced or high-grade MECs are refractory to chemotherapy, often leading to tumor recurrence/metastasis and abysmal ~35% 5-year survival. Causal links ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b130e555acebccd7e5542ec1531fa6c8
https://europepmc.org/articles/PMC8026571/
https://europepmc.org/articles/PMC8026571/
Autor:
Tassiana Souza De Araujo, Rogerio M. Castilho, Carlos H. V. Nascimento-Filho, Paula Monteiro Souza, Cristiane H. Squarize, Gabriel Alvares Borges, Silvia Taveira Elias, Pérola Oliveira Magalhães, Eliete Neves Silva Guerra
Publikováno v:
Clinical and experimental pharmacologyphysiologyREFERENCES. 47(5)
Asparaginase is fundamental to the treatment of haematological malignancies. However, little has been studied on the effects that asparaginase could exert on solid tumours. Thus, this study aimed to evaluate the effects of asparaginase on an oral car
Autor:
Manoela Domingues Martins, Cristiane H. Squarize, Rogerio M. Castilho, Carlos H V Nascimento Filho, Leonardo Amaral Dos Reis, Márcio Ajudarte Lopes, Renata Lucena Markman, Liana Preto Webber, Virgilio Gonzales Zanella, Pablo Agustin Vargas
Publikováno v:
Cellular oncology (Dordrecht). 42(2)
Emerging evidence indicates that bromodomains comprise a conserved class of epigenome readers involved in cancer development and inflammation. Bromodomains are associated with epigenetic modifications of gene transcription through interactions with l