Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Carlos H F Chan"'
Autor:
Yinwen Cheng, Caitlin D Lemke-Miltner, Wattawan Wongpattaraworakul, Carlos H F Chan, Andrean L Simons
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background CMP-001 is a novel Toll-like receptor-9 agonist that consists of an unmethylated CpG-A motif-rich G10 oligodeoxynucleotide (ODN) encapsulated in virus-like particles. In situ vaccination of CMP-001 is believed to activate local tumor-assoc
Externí odkaz:
https://doaj.org/article/c3dc7d83db9b40159de5cdcb3819d943
Autor:
Katelynn Davis, Craig D Dunseth, Sarah L Mott, Kimberly L Cramer-Morales, Ann M Miller, Po Hien Ear, James J Mezhir, Andrew M Bellizzi, Carlos H F Chan
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213576 (2019)
BackgroundNicotinamide phosphoribosyltransferase (NAMPT) plays a key role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), which is a vital cofactor in redox reactions and a substrate for NAD+ consuming enzymes including CD38, PARPs a
Externí odkaz:
https://doaj.org/article/89722a44f10a4529a44e2b6151fc6e91
Autor:
Anna Sintsova, Helen Sarantis, Epshita A Islam, Chun Xiang Sun, Mohsen Amin, Carlos H F Chan, Clifford P Stanners, Michael Glogauer, Scott D Gray-Owen
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004341 (2014)
An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae. Neutrophils undergo an aggressive opsonin-independent response to N. gonorrhoeae, driven by the inna
Externí odkaz:
https://doaj.org/article/8335597d42c142c7b244c8d87da04880
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1353 (2007)
CEA and CEACAM6 are immunoglobulin family intercellular adhesion molecules that are up-regulated without structural mutations in approximately 70% of human cancers. Results in in vitro systems showing tumorigenic effects for these molecules suggest t
Externí odkaz:
https://doaj.org/article/9d449e9a8e67414097b2df4b9805b042
Autor:
Hannah R. Shrader, Aliasger K. Salem, Ann M. Miller, Po Hien Ear, Kristen L Coleman, Ashley McCarthy, Carlos H. F. Chan, Ashutosh K. Mangalam, Ann Tomanek-Chalkley
Publikováno v:
Surgery
Background Introduction of gut flora into the biliary system is common owing to biliary stenting in patients with obstructing pancreatic head cancer. We hypothesize that alteration of biliary microbiome modifies bile content that modulates pancreat
Autor:
Michael I. D’Angelica, Ryan J. Ellis, Jason B. Liu, Brian C. Brajcich, Mithat Gönen, Vanessa M. Thompson, Mark E. Cohen, Susan K. Seo, Emily C. Zabor, Michele L. Babicky, David J. Bentrem, Stephen W. Behrman, Kimberly A. Bertens, Scott A. Celinski, Carlos H. F. Chan, Mary Dillhoff, Matthew E. B. Dixon, Carlos Fernandez-del Castillo, Sepideh Gholami, Michael G. House, Paul J. Karanicolas, Harish Lavu, Shishir K. Maithel, John C. McAuliffe, Mark J. Ott, Bradley N. Reames, Dominic E. Sanford, Umut Sarpel, Courtney L. Scaife, Pablo E. Serrano, Travis Smith, Rebecca A. Snyder, Mark S. Talamonti, Sharon M. Weber, Adam C. Yopp, Henry A. Pitt, Clifford Y. Ko
Publikováno v:
JAMA. 329:1579
ImportanceDespite improvements in perioperative mortality, the incidence of postoperative surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad-spectrum antimicrobial surgical prophylaxis in reducing SSI is poorl
Autor:
Jeremy Chang, Yanan Liu, Stephanie A. Saey, Kevin C. Chang, Hannah R. Shrader, Kelsey L. Steckly, Maheen Rajput, Milan Sonka, Carlos H. F. Chan
Publikováno v:
Frontiers in oncology. 12
IntroductionPancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor prognosis. Surgical resection remains the only potential curative treatment option for early-stage resectable PDAC. Patients with locally advanced or micromet
Autor:
Ashley McCarthy, Pashtoon Murtaza Kasi, Kristen L Coleman, Ann Tomanek-Chalkley, Hannah R. Shrader, Carlos H. F. Chan, Maheen Rajput, Ann M. Miller, Austin G Kazarian, Katie M. Leick
Publikováno v:
Ann Surg Oncol
BACKGROUND: Disease burden in patients with peritoneal carcinomatosis (PC) is difficult to estimate. We evaluated whether peritoneal cell-free tumor DNA can be used as a measure of disease burden. METHODS: Malignant ascites or peritoneal lavage fluid
Autor:
Sue E. Blackwell, Ann M. Miller, Ann Tomanek-Chalkley, Kristen L Coleman, George J. Weiner, Carlos H. F. Chan, Katherine N Gibson-Corely, Caitlin D Lemke-Miltner
Publikováno v:
Ann Surg Oncol
BACKGROUND. The treatment options for patients with peritoneal carcinomatosis (PC) of gastrointestinal and pancreaticobiliary origins are limited. The virus-like particle, CMP-001, composed of the Qβ bacteriophage capsid protein encapsulating a CpG-
Autor:
Ryan P. Merkow, Shu-Yuan Xiao, Francisco J. Izquierdo, Erin W. Gilbert, Michael D. Kluger, Martin D. Goodman, Kaitlyn J. Kelly, Melvy Sarah Mathew, Alejandro Plana, Laura A. Lambert, Brian D. Badgwell, Joshua M. V. Mammen, Daniel E. Abbott, Anand Govindarajan, Aliya N. Husain, Aytekin Oto, H. Richard Alexander, Jason M. Foster, Namrata Setia, Andrew M. Lowy, Travis E. Grotz, Blase N. Polite, Nita Ahuja, Fabian M. Johnston, Colette R. Pameijer, Hedy L. Kindler, Daniel V.T. Catenacci, Robert M. Barone, Konstantinos I. Votanopoulos, T. Clark Gamblin, Joel M. Baumgartner, James C. Cusack, George I. Salti, Callisia N. Clarke, Carla Harmath, Maheswari Senthil, Clifford S. Cho, Mazin Al‐Kasspooles, Joshua H. Winer, Oliver S. Eng, Grace Z. Mak, Giorgos C. Karakousis, Charles Komen Brown, Lucas Sideris, David L. Bartlett, Carlos H. F. Chan, Abraham H. Dachman, Andrea Hayes-Jordan, Kamran Idrees, Kiran K. Turaga, Xavier M. Keutgen, Rhonda K. Yantiss, Vadim Gushchin, Darryl Schuitevoerder, Sean P. Dineen, M. Haroon A. Choudry, James Fleshman, Dan G. Blazer, David Jiang, Daniel M. Labow, Byrne Lee, Scott K. Sherman, Sam G. Pappas, Patricio M. Polanco, Michael G. White, Alexandra Gangi, Sanjay S. Reddy, Marcovalerio Melis, Paul H. Sugarbaker, Ugwuji N. Maduekwe, Nelya Melnitchouk, Farin Amersi, Timothy J. Kennedy, Jeremiah L. Deneve, Lloyd A. Mack, Jesus Esquivel, Sherif Abdel-Misih, Harveshp Mogal, Armando Sardi, Leopoldo J. Fernandez, Sandy Tun, Wilbur B. Bowne, Charles A. Staley, Lana Bijelic, Richard E. Royal, Chukwuemeka Ihemelandu, Joseph Skitzki, Nader Hanna, John M. Kane, Richard N. Berri, Amanda K. Arrington, Georgios V. Georgakis, Jula Veerapong, Mecker G. Möller, Edward A. Levine
Publikováno v:
Cancer. 126:2566-2570
The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of desmoplastic small round cell tumor, breast, and gastrointestinal stromal tumor specifically related to peritoneal surface malignancy. These guidelin