Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Carlos GUTIERREZ-RAMOS"'
Autor:
Marietta Tan, Roland Kolbeck, Daniel Teupser, Stephanos Pavlides, Jose-Carlos Gutierrez-Ramos, Jan L. Breslow
Publikováno v:
Proceedings of the National Academy of Sciences. 101:17795-17800
Fractalkine (CX3CL1) is of particular interest in atherogenesis because it can serve as an adhesion molecule and a chemokine. Fractalkine and its receptor CX3CR1 are expressed in atherosclerotic lesions of humans and mice. However, the effect of frac
Autor:
Jose Carlos Gutierrez-Ramos, Tracy Delaney, Emiko Mizoguchi, William A. Faubion, Stephen Manning, Svend Rietdijk, Atul K. Bhan, Anthony J. Coyle, Cox Terhorst, Ype P. de Jong, Ana C. Abadía-Molina, Kareem Clarke, Jane Tian
Publikováno v:
International Immunology. 16:205-213
Several autoimmune disease models depend on an imbalance in the activation of aggressor T(h)1 and CD4(+)CD25(+) regulatory T (T(reg)) cells. Here we compare the requirement for signals through the co-stimulatory molecules CD28 and inducible co-stimul
Continuous Exposure to House Dust Mite Elicits Chronic Airway Inflammation and Structural Remodeling
Autor:
Beata U. Gajewska, Filip K. Swirski, Ryan E. Wiley, Jose-Carlos Gutierrez-Ramos, Russ Ellis, Jill R. Johnson, Anthony J. Coyle, Mark D. Inman, Manel Jordana, Ramzi Fattouh
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 169:378-385
It is now fully appreciated that asthma is a disease of a chronic nature resulting from intermittent or continued aeroallergen exposure leading to airway inflammation. To investigate responses to continuous antigen exposure, mice were exposed to eith
Publikováno v:
Science. 302:1963-1966
The production of nitric oxide and other reactive nitrogen intermediates (RNI) by macrophages helps to control infection byMycobacterium tuberculosis(Mtb). However, the protection is imperfect and infection persists. To identify genes thatMtbrequires
Autor:
Jose M. Lora, Jaclyn Sicoli, Michael J. Briskin, Kursteen S. Price, Joshua A. Boyce, Savita Bagga, Martin R. Hodge, Jose-Carlos Gutierrez-Ramos, Amal Al-Garawi, Michael D. Pickard
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:1119-1126
Background Mast cells (MCs) proliferate in response to T H 2 cytokines and express genes de novo after activation. Limited information is available concerning the interplay between these events. Objective We explored the potential for T H 2 cytokines
Autor:
Thomas Kamradt, Alberto Sanchez-Fueyo, Vijay K. Kuchroo, Orissa Bender, Jane Tian, Jose-Carlos Gutierrez-Ramos, Terry B. Strom, Dominic Picarella, Catherine A. Sabatos, Natasha Manlongat, Anthony J. Coyle, Christoph Domenig, Xin Xiao Zheng
Publikováno v:
Nature Immunology. 4:1093-1101
Although T helper (T(H)) cell-mediated immunity is required to effectively eliminate pathogens, unrestrained T(H) activity also contributes to tissue injury in many inflammatory and autoimmune diseases. We report here that the T(H) type 1 (T(H)1)-spe
Publikováno v:
Seminars in Immunology. 15:225-231
Remarkable advances in our knowledge of the genome sequence have led to the creation of databases that afford the opportunity to discover genes based on the presence of specific sequence motifs. The application of this strategy to the identification
Autor:
Vicente Arroyo, Pau Sancho-Bru, Josep M. Nicolás, Jose M. Lora, Wladimiro Jiménez, Pere Ginès, Nadine S. Weich, Amal Al-Garawi, Jose-Carlos Gutierrez-Ramos, Jordi Colmenero, Juan Rodés, Ramon Bataller, Manel Solé
Publikováno v:
Gastroenterology. 125:117-125
Background & aims: The renin-angiotensin system plays an important role in hepatic fibrogenesis. In other organs, myofibroblasts accumulated in damaged tissues generate angiotensin II, which promotes inflammation and extracellular matrix synthesis. I
Autor:
Konstantinos A. Papadakis, Stephan R. Targan, Martin R. Hodge, Carol J. Landers, Sofia T. Moreno, Jose-Carlos Gutierrez-Ramos, John Prehn, Elias A. Kouroumalis
Publikováno v:
The Journal of Immunology. 171:159-165
The chemokine receptor CCR9 is expressed on most small intestinal lamina propria and intraepithelial lymphocytes and on a small subset of peripheral blood lymphocytes. CCR9-expressing lymphocytes may play an important role in small bowel immunity and
Autor:
David Alvarez, Elizabeth C. Cates, José-Carlos Gutierrez-Ramos, Anthony J. Coyle, Manel Jordana, Beata U. Gajewska, Susanna Goncharova, Ramzi Fattouh
Publikováno v:
Journal of Allergy and Clinical Immunology. 111:1076-1086
Background: Conventional models of allergic airway inflammation involve intraperitoneal administration of ovalbumin in conjunction with a chemical adjuvant (generally aluminum hydroxide) to generate allergic airways inflammation. Here we have investi