Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carlos G. Urzúa-Traslaviña"'
Autor:
Carlos G. Urzúa-Traslaviña, Tijs van Lieshout, Floranne Boulogne, Kevin Domanegg, Mahmoud Zidan, Olivier B. Bakker, Annique Claringbould, Jeroen de Ridder, Wilbert Zwart, Harm-Jan Westra, Patrick Deelen, Lude Franke
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background The genetic background of cancer remains complex and challenging to integrate. Many somatic mutations within genes are known to cause and drive cancer, while genome-wide association studies (GWAS) of cancer have revealed many germ
Externí odkaz:
https://doaj.org/article/87d4375406f84fe0ab53a48e271de9a9
Autor:
Carlos G. Urzúa-Traslaviña, Vincent C. Leeuwenburgh, Arkajyoti Bhattacharya, Stefan Loipfinger, Marcel A. T. M. van Vugt, Elisabeth G. E. de Vries, Rudolf S. N. Fehrmann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Our understanding of the function of many transcripts is still incomplete, limiting the interpretability of transcriptomic data. Here the authors use consensus-independent component analysis, together with a guilt-by-association approach, to improve
Externí odkaz:
https://doaj.org/article/4a0123198db1432b8cd7b6fe248572ba
Autor:
Arkajyoti Bhattacharya, Rico D. Bense, Carlos G. Urzúa-Traslaviña, Elisabeth G. E. de Vries, Marcel A. T. M. van Vugt, Rudolf S. N. Fehrmann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Copy number alterations (CNAs) can drive tumor progression in cancer by altering gene expression levels, but transcriptional adaption can skew CNA impact. Here, the authors present transcriptional adaptation to CNA (TACNA) profiling; a tool to extrac
Externí odkaz:
https://doaj.org/article/8a30eeb79fbb4839b329f70a9a9b4653
Autor:
Arkajyoti Bhattacharya, Carlos G. Urzúa-Traslaviña, Marcel A. T. M. van Vugt, Rudolf S. N. Fehrmann
Publikováno v:
Cancer Research. 82:5019-5019
The Cancer Dependency Map project (DepMap) aims to identify cancer vulnerabilities through the in vitro study of genetic dependencies in cancer cell lines using CRISPR/Cas9 loss-of-function screens. Cas9-mediated DNA break formation induces toxic eff
Autor:
Steven de Jong, Arkajyoti Bhattacharya, Carlos G. Urzúa-Traslaviña, Vincent Christiaan Leeuwenburgh, Rudolf S N Fehrmann, Marthe T. C. Walvoort, Mathilde Jalving
Publikováno v:
SSRN Electronic Journal.
Patient-derived bulk expression profiles of cancers can provide insight into transcriptional changes that underlie reprogrammed metabolism in cancer. However, these bulk profiles represent the average expression pattern of all heterogeneous tumor and
Autor:
Carlos G Urzúa Traslaviña, María Guadalupe Moreno Treviño, Denisse Aideé Martínez-Treviño, Hugo A. Barrera-Saldaña, Rafael Baltazar Reyes León Cachón
Publikováno v:
Journal of Genetics and Genome Research. 1