Liver targeted gene therapy: Insights into emerging therapies

Autor: Clifford J. Steer, Carlos G. Moscoso

Publikováno v: Drug Discovery Today: Technologies. 34:9-19

The large number of monogenic metabolic disorders originating in the liver poses a unique opportunity for development of gene therapy modalities to pursue curative approaches. Various disorders have been successfully treated via liver-directed gene t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c0f1d63027c7ba9d579cc9af98df17
https://doi.org/10.1016/j.ddtec.2020.11.001

Aceruloplasminemia: A Case Report and Review of a Rare and Misunderstood Disorder of Iron Accumulation

Autor: Chimaobi M. Anugwom, Nicholas Lim, Mohamed Hassan, Carlos G. Moscoso

Publikováno v: Cureus

Aceruloplasminemia is a rare disorder of iron accumulation inherited in an autosomal recessive fashion. It commonly presents as chronic microcytic anemia, and then progresses to signs and symptoms that are due to the accumulation of iron in multiple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59adf822ada69619bae3f089a5cc297
http://europepmc.org/articles/PMC7755722

Precision medicine, agriculture, and genome editing: science and ethics

Autor: Shaoyuan Tan, Kavita M. Berger, Kelly R. Potz, Carlos G. Moscoso, Clifford J. Steer, Pamala A. Jacobson

Publikováno v: Annals of the New York Academy of SciencesReferences. 1465(1)

The era of precision medicine has generated advances in various fields of science and medicine with the potential for a paradigm shift in healthcare delivery that will ultimately lead to an individualized approach to medicine. Such timely topics were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc49328c11da5fb97142146ba051d89
https://pubmed.ncbi.nlm.nih.gov/31721233

Contributors

Autor: Nur Elina Abdul Mutalib, Bianca de Almeida-Pittito, Ana Clara Matoso Montuori de Andrade, José Luiz de Brito Alves, L. Caetano M. Antunes, M.J. Arias-Tellez, Panduro Arturo, R. Awais, Camille de Moura Balarini, Dibyajyoti Banerjee, Thais Fernanda Bartelli, Paulo José Basso, Soumeya Bekri, Rajasri Bhattacharyya, Aleksandr Birg, Natália Alvarenga Borges, Valdir de Andrade Braga, Nicholas Buys, Niels Olsen Saraiva Câmara, Agostinho Carvalho, Maria Dolores Luque de Castro, Luiz Gonzaga Vaz Coelho, Nathaniel Aviv Cohen, Kevin C. Conlon, Ramon V. Cortez, Cláudia A. Couto, Josiane de Campos Cruz, Cristina Cunha, P. D'Amelio, Dinesh Kumar Dahiya, Arun Kumar Dangi, Emmanuel Dias-Neto, Cláudio Duarte-Oliveira, Sinead N. Duggan, Alex Escalona, Joel Faintuch, Jacob J. Faintuch, Salomao Faintuch, Luciana Costa Faria, Carla Fernández-Reynoso, Silvia M. Ferolla, Maria de Lourdes A. Ferrari, Teresa C.A. Ferrari, Nicole V. Ferreira, Sandra Roberta G. Ferreira, Rosana B.R. Ferreira, Manuel Ferrer, Jarlei Fiamoncini, Hooi Ling Foo, Damodar Gajurel, Daniel Garrido, A. Gil, Shailendra Giri, Thaís Glatthardt, Samuel M. Gonçalves, Alexandra Grill, Emily K. Hendrix, Aline Ignacio, M. Íñiguez, Rosa Jorba, N. Kapel, Trevor O. Kirby, Anastasios Koulaouzidis, Deepak Kumar, Fulvio Lauretani, Henry C. Lin, Iara M. Linhares, Teck Chwen Loh, Igor Loniewski, Mateus Eustáquio Moura Lopes, Denise Mafra, Marciane Magnani, Nitsan Maharshak, Danish J. Malik, Ashutosh Mangalam, Kunal Maniar, Wojciech Marlicz, M.Carmen. Martínez-Cuesta, Robert Memba, Tiziana Meschi, Christian Milani, Evelyn Minis, Amal Moideen, Ana Carolina F. Moraes, Luana N. Moreira, Carlos G. Moscoso, Marcelle M. Nascimento, Andrew Nelson, E. Neumann, Krista M. Newman, J.R. Nicoli, Antonio Nouvenne, Javier Ochoa-Repáraz, Claudia Ojeda-Granados, Gislane Lellis Vilela de Oliveira, J.A. Oteo, L.R. Pace, Rigoberto Pallares-Méndez, R.D. Parker, Kalpesh G. Patel, Heidi Pauer, Mathilde Payen, Carmen. Peláez, Murilo Pereira, Marina Perez-Gordo, P. Pérez-Matute, J. Plaza-Diaz, F. Priego-Capote, Anil Kumar Puniya, Nikolaos T. Pyrsopoulos, Beata Anna Raczkowska, Raha Abdul Rahim, Christoph Reinhardt, null Renuka, Teresa Requena, J. Reygner, Nathaniel L. Ritz, Ingrid Rivera-Iñiguez, Renata Robial, David Rojo, Sonia Roman, Clotilde Rousseau, F.J. Ruiz-Ojeda, M.J. Saez-Lara, Liliane Martins dos Santos, F. Sassi, Umesh K. Shandilya, P. Shrestha, Pratyoosh Shukla, Vandana Singh, Karolina Skonieczna-Żydecka, Camila Solar, P. Solis-Urra, Evandro Leite de Souza, Charikleia Stefanaki, Christopher J. Stewart, Jing Sun, Carla R. Taddei, Claudio Tana, Abdellah Tebani, Fernanda Fernandes Terra, Andrea Ticinesi, Byron P. Vaughn, Marco Ventura, Hubert Vidal, L.Q. Vieira, M.J. Villanueva-Millán, Ingrid Kazue Mizuno Watanabe, C.M. Wells, Steven S. Witkin, T.Y. Wong, Chenghong Yin, Elisa Zubeldia-Varela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59d0b20e0d47c606f98e44f28a941e0c
https://doi.org/10.1016/b978-0-12-815249-2.01002-2

HIV-1 Tat protein induces viral internalization through Env-mediated interactions in dose-dependent manner

Autor: Selina Poon, R. Holland Cheng, Prasanna R. Kolatkar, Anders Vahlne, Carlos G. Moscoso, Onur M. Yenigun

Publikováno v: AIDS. 27:2355-2364

OBJECTIVE To study the dose-dependent manner of HIV-1 Tat-induced effects on viral replication, internalization and spread, and to directly observe these effects on soluble Env immunogens and virus-like particles. DESIGN In order to determine the man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8ac4da063a4b434d918f5d690f0b44
https://doi.org/10.1097/01.aids.0000432452.83604.59