Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Carlos Farkas"'
Autor:
Maryori González, Felipe Maurelia, Jaime Aguayo, Roberto Amigo, Rodrigo Arrué, José Leonardo Gutiérrez, Marcela Torrejón, Carlos Farkas, Teresa Caprile
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-19 (2024)
Abstract Background The significant role of embryonic cerebrospinal fluid (eCSF) in the initial stages of brain development has been thoroughly studied. This fluid contains crucial molecules for proper brain development such as members of the Wnt and
Externí odkaz:
https://doaj.org/article/4a61268de05e4c71bb5e8a232e330518
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106640- (2024)
Degenerative cervical myelopathy (DCM) describes a spectrum of disorders that cause progressive and chronic cervical spinal cord compression. The clinical presentation can be complex and can include locomotor impairment, hand and upper extremity dysf
Externí odkaz:
https://doaj.org/article/8397f2c21b2f4227ab26bacf917a98df
Autor:
Diego Cuevas, Roberto Amigo, Adolfo Agurto, Adan Andreu Heredia, Catherine Guzmán, Antonia Recabal-Beyer, Valentina González-Pecchi, Teresa Caprile, Jody J. Haigh, Carlos Farkas
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1915 (2024)
Acute myeloid leukemia (AML) is a diverse malignancy originating from myeloid progenitor cells, with significant genetic and clinical variability. Modern classification systems like those from the World Health Organization (WHO) and European Leukemia
Externí odkaz:
https://doaj.org/article/31d10ff71daa431d93590ea83d487fdb
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Degenerative Cervical Myelopathy (DCM) is the most common cause of spinal cord impairment in elderly populations. It describes a spectrum of disorders that cause progressive spinal cord compression, neurological impairment, loss of bladder and bowel
Externí odkaz:
https://doaj.org/article/f6385fa0dbb74bacb0e03f00d7d09717
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15245 (2023)
The establishment and maintenance of nucleosome-free regions (NFRs) are prominent processes within chromatin dynamics. Transcription factors, ATP-dependent chromatin remodeling complexes (CRCs) and DNA sequences are the main factors involved. In Sacc
Externí odkaz:
https://doaj.org/article/b3f1873ae4114c14acd0d8f2d904cbbb
Autor:
María José Oviedo, Eder Ramírez, Manuel Cifuentes, Carlos Farkas, Andy Mella, Romina Bertinat, Roberto Gajardo, Luciano Ferrada, Nery Jara, Isabelle De Lima, Fernando Martínez, Francisco Nualart, Katterine Salazar
Publikováno v:
Cells, Vol 11, Iss 20, p 3327 (2022)
The identification of new proteins that regulate the function of one of the main cellular phosphatases, protein phosphatase 1 (PP1), is essential to find possible pharmacological targets to alter phosphatase function in various cellular processes, in
Externí odkaz:
https://doaj.org/article/f556566cb26d4a3ca86a433318a290b7
Autor:
Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nick Wong, Danny Huylebroeck, Marc P Stemmler, Simone Brabletz, Thomas Brabletz, Christian M Nefzger, Steven Goossens, Geert Berx, Jose M Polo, Jody J Haigh
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001394 (2021)
The ZEB2 transcription factor has been demonstrated to play important roles in hematopoiesis and leukemic transformation. ZEB1 is a close family member of ZEB2 but has remained more enigmatic concerning its roles in hematopoiesis. Here, we show using
Externí odkaz:
https://doaj.org/article/924fefc9d60f4750bd8231e082078d7c
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
An unprecedented amount of SARS-CoV-2 sequencing has been performed, however, novel bioinformatic tools to cope with and process these large datasets is needed. Here, we have devised a bioinformatic pipeline that inputs SARS-CoV-2 genome sequencing i
Externí odkaz:
https://doaj.org/article/bb07a6df8bb949c19a1bd18ec8459638
Autor:
Carlos Farkas, Aracelly Quiroz, Claudia Alvarez, Viviana Hermosilla, Carlos F. Aylwin, Alejandro Lomniczi, Ariel F. Castro, Matias I. Hepp, Roxana Pincheira
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to canc
Externí odkaz:
https://doaj.org/article/6932d3d8158c4b3a8e4533cb678e9058
Autor:
Carlos Farkas, Francisco Fuentes-Villalobos, Jose Luis Garrido, Jody Haigh, María Inés Barría
Publikováno v:
PeerJ, Vol 8, p e9255 (2020)
Here we aim to describe early mutational events across samples from publicly available SARS-CoV-2 sequences from the sequence read archive and GenBank repositories. Up until 27 March 2020, we downloaded 50 illumina datasets, mostly from China, USA (W
Externí odkaz:
https://doaj.org/article/6bdaacd0267e4306bd93aeb4caebaefe