Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Carlos Estevez Fraga"'
Autor:
Yara Refaat Hassan, Filipe Brogueira Rodrigues, Paul Zeun, Lauren M. Byrne, Carlos Estevez-Fraga, Rosanna Tortelli, Rachael I. Scahill, Edward J. Wild, Sarah J. Tabrizi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Lumbar puncture (LP) has become increasingly common for people with Huntington’s disease (HD) both to administer intrathecal investigational medicinal products and to collect cerebrospinal fluid to develop biological markers to track disea
Externí odkaz:
https://doaj.org/article/ad4a5e730417443781456cf2e0327ad6
Progressive alterations in white matter microstructure across the timecourse of Huntington's disease
Autor:
Carlos Estevez‐Fraga, Michael S. Elmalem, Marina Papoutsi, Alexandra Durr, Elin M. Rees, Nicola Z. Hobbs, Raymund A. C. Roos, Bernhard Landwehrmeyer, Blair R. Leavitt, Douglas R. Langbehn, Rachael I. Scahill, Geraint Rees, Sarah J. Tabrizi, Sarah Gregory
Publikováno v:
Brain and Behavior, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Background Whole‐brain longitudinal diffusion studies are crucial to examine changes in structural connectivity in neurodegeneration. Here, we investigated the longitudinal alterations in white matter (WM) microstructure across the timecou
Externí odkaz:
https://doaj.org/article/14760f7b295f464cbc8b231b3d170168
Autor:
Eileanoir B. Johnson, Christopher S. Parker, Rachael I. Scahill, Sarah Gregory, Marina Papoutsi, Paul Zeun, Katherine Osborne-Crowley, Jessica Lowe, Akshay Nair, Carlos Estevez-Fraga, Kate Fayer, Geraint Rees, Hui Zhang, Sarah J. Tabrizi
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103266- (2021)
Background: Pathological processes in Huntington's disease (HD) begin many years prior to symptom onset. Recently we demonstrated that in a premanifest cohort approximately 24 years from predicted disease onset, despite intact function, there was evi
Externí odkaz:
https://doaj.org/article/a5b119aef0874e58add8c97f8d4a0310
Publikováno v:
Journal of Huntington's Disease. 11:351-367
In this edition of the Huntington’s Disease Clinical Trials Corner, we expand on the PIVOT HD (PTC518), and SIGNAL (pepinemab) trials, and list all currently registered and ongoing clinical trials in Huntington’s disease. We also introduce a ‘b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323ef2031bd47e005dc000ae5a26c213
https://doi.org/10.3233/jhd-229006
https://doi.org/10.3233/jhd-229006
Publikováno v:
Journal of Huntington's Disease. 11:105-118
In this edition of the Huntington’s Disease Clinical Trials Corner we expand on GENERATION HD1, PRECISION-HD1 and PRECISION-HD2, SELECT-HD, and VIBRANT-HD trials, and list all currently registered and ongoing clinical trials in Huntington’s disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b048fb5ec80961f3a969bf0094e475
https://doi.org/10.3233/jhd-229002
https://doi.org/10.3233/jhd-229002
Autor:
Francesca Magrinelli, Ishani Rajapaksha, Christopher Kobylecki, Anna Latorre, Eoin Mulroy, Carlos Estevez‐Fraga, Henry Houlden, Michele Tinazzi, Kailash P. Bhatia
Publikováno v:
Movement Disorders. 37:658-662
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2905b7d869020806cc0b38d0481586
https://doi.org/10.1002/mds.28955
https://doi.org/10.1002/mds.28955
Autor:
null Carlos Estevez‐Fraga, null Michael S. Elmalem, null Marina Papoutsi, null Alexandra Durr, null Elin M. Rees, null Nicola Z. Hobbs, null Raymund A. C. Roos, null Bernhard Landwehrmeyer, null Blair R. Leavitt, null Douglas R. Langbehn, null Rachael I. Scahill, null Geraint Rees, null Sarah J. Tabrizi, null Sarah Gregory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14bc68627b3897b4161c7070f737513f
https://doi.org/10.1002/brb3.2940/v2/response1
https://doi.org/10.1002/brb3.2940/v2/response1
Autor:
Carlos Estevez-Fraga, Maria Molina-Sanchez, Rodrigo Alvarez-Velasco, Pablo Agüero-Rabes, Leticia Crespo-Araico, Elena Viedma-Guiard, Antonio Cruz-Culebras, Consuelo Matute, Rocio Vera, Alicia De Felipe-Mimbrera, Jaime Masjuan Vallejo
Publikováno v:
Stroke Research and Treatment, Vol 2018 (2018)
Introduction. Patients treated with vitamin K antagonists (VKA) are at increased risk of intracranial haemorrhage (ICH). The purpose of our study was to determine the quality of previous anticoagulation control in patients with VKA-associated ICH. Ma
Externí odkaz:
https://doaj.org/article/e4d8357d682e44ae841befa23833e2b7
Autor:
Marina, Papoutsi, Michael, Flower, Davina J, Hensman Moss, Peter, Holmans, Carlos, Estevez-Fraga, Eileanoir B, Johnson, Rachael I, Scahill, Geraint, Rees, Douglas, Langbehn, Sarah J, Tabrizi, Bernhard, Landwehrmeyer
Publikováno v:
Brain Communications. 4
An important step towards the development of treatments for cognitive impairment in ageing and neurodegenerative diseases is to identify genetic and environmental modifiers of cognitive function and understand the mechanism by which they exert an eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b231440f44a9e5a993d6f99abda2189e
https://doi.org/10.1093/braincomms/fcac279
https://doi.org/10.1093/braincomms/fcac279
Autor:
Enza Maria Valente, Kailash P. Bhatia, Antonio Pisani, Giulia Di Lazzaro, Carlos Estevez-Fraga, Francesca Magrinelli
Publikováno v:
Movement Disorders. 36:1511-1525
X-linked parkinsonism encompasses rare heterogeneous disorders mainly inherited as a recessive trait, therefore being more prevalent in males. Recent developments have revealed a complex underlying panorama, including a spectrum of disorders in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ece04c07daa26074339d3af3ba56c7
https://doi.org/10.1002/mds.28565
https://doi.org/10.1002/mds.28565