Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carlos E. Sanz-Rodríguez"'
Autor:
Carlos E. Sanz-Rodríguez, Benjamin Hoffman, Paul J. Guyett, Andrei Purmal, Baljinder Singh, Michael P. Pollastri, Kojo Mensa-Wilmot
Publikováno v:
Mol Pharmacol
CBL0137 is a lead drug for human African trypanosomiasis, caused by Trypanosoma brucei. Herein, we use a four-step strategy to 1) identify physiologic targets and 2) determine modes of molecular action of CBL0137 in the trypanosome. First, we identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23305b40f90484af006600943a6ecd4
https://europepmc.org/articles/PMC9341264/
https://europepmc.org/articles/PMC9341264/
Autor:
Amrita Sharma, Carlos E. Sanz-Rodriguez, Michael P. Pollastri, Andrei Purmal, Kojo Mensa-Wilmot
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
The criteria for the progression of hits in the discovery of leads for human African trypanosomiasis (HAT), a neglected disease caused by the microbial eukaryote Trypanosoma brucei, are not standardized. Hits are advanced upon meeting thresholds for
Externí odkaz:
https://doaj.org/article/65e49f0f758847c6b3614b0c90b244f6
Publikováno v:
World journal of biological chemistry. 5(2)
To investigate the interaction of reconstituted rhodopsin, 9-cis-retinal-rhodopsin and 13-cis-retinal-rhodopsin with transducin, rhodopsin kinase and arrestin-1.Rod outer segments (ROS) were isolated from bovine retinas. Following bleaching of ROS me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63a3bd00d1fbb4c7226aaf8426c6742c
https://pubmed.ncbi.nlm.nih.gov/24921014
https://pubmed.ncbi.nlm.nih.gov/24921014
Publikováno v:
The Journal of biological chemistry. 282(17)
Trypanosoma cruzi, the etiologic agent of Chagas disease, has an unusual ATP-dependent hexokinase (TcHK) that is not affected by D-glucose 6-phosphate, but is non-competitively inhibited by inorganic pyrophosphate (PP(i)), suggesting a heterotropic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a80f3918a9cd150b6e88d24a6685ab2
https://pubmed.ncbi.nlm.nih.gov/17329254
https://pubmed.ncbi.nlm.nih.gov/17329254
Autor:
Araujo NA; Nelson A Araujo, Carlos E Sanz-Rodríguez, José Bubis, Departamento de Biología Celular, Universidad Simón Bolívar, Caracas 1081-A, Venezuela., Sanz-Rodríguez CE; Nelson A Araujo, Carlos E Sanz-Rodríguez, José Bubis, Departamento de Biología Celular, Universidad Simón Bolívar, Caracas 1081-A, Venezuela., Bubis J; Nelson A Araujo, Carlos E Sanz-Rodríguez, José Bubis, Departamento de Biología Celular, Universidad Simón Bolívar, Caracas 1081-A, Venezuela.
Publikováno v:
World journal of biological chemistry [World J Biol Chem] 2014 May 26; Vol. 5 (2), pp. 254-68.