Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carlos E. Espinosa"'
Autor:
Víctor Pérez Medina Martínez, Miriam Cedillo Robles, Laura Carmina Juárez-Bayardo, Carlos E. Espinosa-de la Garza, Angélica Meneses, Néstor O. Pérez
Publikováno v:
AAPS PharmSciTech. 23(7)
Rituximab is a monoclonal antibody used in the treatment of lymphoma non-Hodgkin. This mAb is photosensitive as it is administrated to the patient by infusion/perfusion; therefore, photostability is a decisive factor in the efficacy of this biologic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191cfb12453951ff020c082930f91537
https://pubmed.ncbi.nlm.nih.gov/36175743
https://pubmed.ncbi.nlm.nih.gov/36175743
Autor:
Luis F. Flores-Ortiz, Néstor O. Pérez, Víctor Pérez Medina Martínez, Diego A. Méndez-Silva, Mariana Bolívar-Vichido, Carlos E. Espinosa-de la Garza
Publikováno v:
AAPS PharmSciTech. 19:1672-1680
Silver nanoparticles (AgNPs) are known to interact with proteins, leading to modifications of the plasmonic absorption that can be used to monitor this interaction, entailing a promising application for sensing adsorption of therapeutic proteins in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224d60a81825178452171ee0093aa0ff
https://doi.org/10.1208/s12249-018-0983-6
https://doi.org/10.1208/s12249-018-0983-6
Autor:
Antonio Germán Hernández-García, Carlos E. Espinosa-de la Garza, Néstor O. Pérez, Víctor Pérez Medina Martínez
Publikováno v:
Analytical and bioanalytical chemistry. 412(8)
Biopharmaceuticals are in direct contact with different plastic materials, which can contribute to process-related impurities. Polyethylene terephthalate glycol (PETG) is used for storage and transportation of biopharmaceuticals and it is synthetized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba8ec4afdd0d143362815d5edbddba4
https://pubmed.ncbi.nlm.nih.gov/31982923
https://pubmed.ncbi.nlm.nih.gov/31982923
Autor:
Carlos E. Espinosa-de la Garza, Luis F. Flores-Ortiz, Víctor R. Campos-García, Emilio Medina-Rivero, Jesús Padilla-Calderón, Carlos A. López-Morales, Eleuterio Benites-Zaragoza, Armando Jiménez-Miranda, Daniel Herrera-Fernández, Néstor O. Pérez
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 132:133-140
Complex pharmaceuticals are in demand of competent analytical methods able to analyze charge heterogeneity as a critical quality attribute (CQA), in compliance with current regulatory expectations. A notorious example is glatiramer acetate (GA), a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383160b012f8fd48a2bcf499fee8fed4
https://doi.org/10.1016/j.jpba.2016.10.002
https://doi.org/10.1016/j.jpba.2016.10.002
Autor:
Lilia Tierrablanca-Sánchez, Carlos E. Espinosa-de la Garza, Víctor Pérez Medina Martínez, Germán González Santoyo, Laura C. Juárez-Bayardo, Nelly Piña-Lara, Néstor O. Pérez
Publikováno v:
European Journal of Pharmaceutical Sciences. 153:105467
Etanercept is a biotechnological product that has a complex glycosylation profile. To elucidate Etanercept glycosylation effect over biological activity and stability, we deglycosylated sequentially this molecule. Sequential deglycosylation was perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d416c5b565cab1aedc96d627a90aed7
https://doi.org/10.1016/j.ejps.2020.105467
https://doi.org/10.1016/j.ejps.2020.105467
Autor:
Mariana P. Miranda-Hernández, Lilia Acosta-Flores, Luis F. Flores-Ortiz, Néstor O. Pérez, Emilio Medina-Rivero, Carlos E. Espinosa-de la Garza
Publikováno v:
Journal of Separation Science. 38:1537-1543
Analysis of the physical properties of biotherapeutic proteins is crucial throughout all the stages of their lifecycle. Herein, we used size-exclusion ultra high performance liquid chromatography coupled to multiangle light scattering and refractive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5080044016dd65a0bb0d814288535b25
https://doi.org/10.1002/jssc.201400863
https://doi.org/10.1002/jssc.201400863
Autor:
Luis Vallejo-Castillo, Isabel Gracia-Mora, Néstor O. Pérez, Leslie Muñoz-García, Rodolfo Salazar-Ceballos, Luis F. Flores-Ortiz, Daniel Herrera-Fernández, Carlos E. Espinosa-de la Garza, Lenin Pavón, Sonia Mayra Pérez-Tapia, Emilio Medina-Rivero, Víctor R. Campos-García, Sandra Avila, German González
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Glatiramer Acetate (GA) is an immunomodulatory medicine approved for the treatment of multiple sclerosis, whose mechanisms of action are yet to be fully elucidated. GA is comprised of a complex mixture of polypeptides with different amino acid sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad775b469704d35eaac7912e027350f
https://doi.org/10.1038/s41598-017-12416-1
https://doi.org/10.1038/s41598-017-12416-1
Autor:
Francisco C. Perdomo-Abúndez, Carlos E. Espinosa-de la Garza, Jaime M. Uribe-Wiechers, Jesús Padilla-Calderón, Luis F. Flores-Ortiz, Néstor O. Pérez, Emilio Medina-Rivero
Publikováno v:
ELECTROPHORESIS. 34:1133-1140
Analytical platforms that characterize charge heterogeneity in therapeutic proteins, such as mAbs, are important tools that can be used to define quality attributes. CZE separates protein moieties close to their native state and is a valuable physico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b259ce5dbd8e8f94dbbeaf165a8a224
https://doi.org/10.1002/elps.201200575
https://doi.org/10.1002/elps.201200575
Autor:
Luis F. Flores-Ortiz, Néstor O. Pérez, Emilio Medina-Rivero, Carlos E. Espinosa-de la Garza, Rodolfo D. Salazar-Flores
Publikováno v:
Journal of Visualized Experiments.
Biotherapeutic proteins, such as monoclonal antibodies (mAbs), are feasible alternatives for the treatment of chronic-degenerative diseases. The biological activity of these proteins depends on their physicochemical properties. The use of high-perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce2f4b39f092cc91a0814757bd14b72
https://doi.org/10.3791/55082
https://doi.org/10.3791/55082
Publikováno v:
Langmuir. 26:16941-16948
The electrostatic stabilization of colloidal dispersions is usually considered the domain of polar media only because of the high energetic cost associated with introducing electric charge in nonpolar environments. Nevertheless, some surfactants refe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bfc8bf68e67e614cc411b71eac7859
https://doi.org/10.1021/la1033965
https://doi.org/10.1021/la1033965