Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Carlos E. Castro"'
Autor:
Ariel Robbins, Hazen Hildebolt, Michael Neuhoff, Peter Beshay, Jessica O. Winter, Carlos E. Castro, Ralf Bundschuh, Michael G. Poirier
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Biomolecular systems are dependent on a complex interplay of forces. Modern force spectroscopy techniques provide means of interrogating these forces, but they are not optimized for studies in constrained environments as they require attachm
Externí odkaz:
https://doaj.org/article/9d8b1719f3fd49ac8789b779e7d5820d
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract DNA origami nanodevices achieve programmable structure and tunable mechanical and dynamic properties by leveraging the sequence‐specific interactions of nucleic acids. Previous advances have also established DNA origami as a useful buildin
Externí odkaz:
https://doaj.org/article/975dfabfd0384b7eaee83963ca7d127c
Autor:
Ehsan Akbari, Melika Shahhosseini, Ariel Robbins, Michael G. Poirier, Jonathan W. Song, Carlos E. Castro
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Single molecule force spectroscopy methods are often low throughput and have high instrument cost. Here the authors report FLO-Chip, a low-cost, high throughput technique using microfluidics for multiplexed mechanical manipulation of many individual
Externí odkaz:
https://doaj.org/article/88018e100aa44999993ef068c1501908
Autor:
Yuchen Wang, Anjelica Kucinic, Lilly Des Rosiers, Peter E. Beshay, Nicholas Wile, Michael W. Hudoba, Carlos E. Castro
Publikováno v:
Applied Sciences, Vol 13, Iss 5, p 3208 (2023)
DNA origami (DO) nanotechnology has strong potential for applications including molecular sensing, drug delivery, and nanorobotics that rely on nanoscale structural precision and the ability to tune mechanical and dynamic properties. Given these emer
Externí odkaz:
https://doaj.org/article/c3e8df7a5be44148ba55cbb31d2d476c
Autor:
Stephanie Lauback, Kara R. Mattioli, Alexander E. Marras, Maxim Armstrong, Thomas P. Rudibaugh, Ratnasingham Sooryakumar, Carlos E. Castro
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
DNA molecular machines hold promise for biological nanotechnology, but how to actuate them in a fast and programmable manner remains challenging. Here, Lauback et al. demonstrate direct manipulation of DNA origami assemblies via a micrometer-long sti
Externí odkaz:
https://doaj.org/article/12a5b4303f2c454cb20a60acd75c1dd5
Autor:
Dongsheng Lei, Alexander E. Marras, Jianfang Liu, Chao-Min Huang, Lifeng Zhou, Carlos E. Castro, Hai-Jun Su, Gang Ren
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Scaffolded DNA origami by folding single-stranded DNA into three-dimensional nanostructures holds promise for building functional nanomachines, yet their dynamic structures remain largely unknown. Here, Lei et al. address this issue using individual-
Externí odkaz:
https://doaj.org/article/e5bbc34f4cf04f439e397eb2179d2fff
Autor:
Yuchen Wang, Sebastian Sensale, Miguel Pedrozo, Chao-Min Huang, Michael G. Poirier, Gaurav Arya, Carlos E. Castro
Publikováno v:
ACS Nano. 17:8271-8280
Autor:
Marcello DeLuca, Wolfgang G. Pfeifer, Benjamin Randoing, Chao-Min Huang, Michael G. Poirier, Carlos E. Castro, Gaurav Arya
Publikováno v:
Nanoscale. 15:8356-8365
Control over the mesoscale to microscale patterning of materials is of great interest to the soft matter community. Inspired by DNA origami rotors, we introduce a 2D nearest-neighbor lattice of spinning rotors that exhibit discrete orientational stat
Publikováno v:
Nanoscale. 15:562-572
Structural DNA nanotechnology has enabled the design and construction of complex nanoscale structures with precise geometry and programmable dynamic and mechanical properties. Recent efforts have led to major advances in the capacity to actuate shape
Autor:
Melika Shahhosseini, Peter E. Beshay, Ehsan Akbari, Niksa Roki, Christopher R. Lucas, Alex Avendano, Jonathan W. Song, Carlos E. Castro
Publikováno v:
ACS Applied Materials & Interfaces. 14:55307-55319
The interactions of cells with signaling molecules present in their local microenvironment maintain cell proliferation, differentiation, and spatial organization and mediate progression of diseases such as metabolic disorders and cancer. Real-time mo