Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.

Autor: Alberto Diaz de Leon, Jennifer T Cronkhite, Anna-Luise A Katzenstein, J David Godwin, Ganesh Raghu, Craig S Glazer, Randall L Rosenblatt, Carlos E Girod, Edward R Garrity, Chao Xing, Christine Kim Garcia

Publikováno v: PLoS ONE, Vol 5, Iss 5, p e10680 (2010)

Telomerase is an enzyme that catalyzes the addition of nucleotides on the ends of chromosomes. Rare loss of function mutations in the gene that encodes the protein component of telomerase (TERT) have been described in patients with idiopathic pulmona

Externí odkaz: https://doaj.org/article/fd1501fde8a94ec7b8fafef226b711f5

Results and lessons from a hospital-wide initiative incentivised by delivery system reform to improve infection prevention and sepsis care

Autor: Judith Herrington, Karen Garvey, Carlos E. Girod, Karla Voy-Hatter, Fred P. Cerise, Christopher J. Madden, Pranavi Sreeramoju, Calvin White, Joseph P. Minei, Abu Minhajuddin, Robert W. Haley, Rosechelle M. Ruggiero

Publikováno v: BMJ Open Quality, Vol 10, Iss 1 (2021)
BMJ Open Quality

BackgroundAn academic safety-net hospital leveraged the federally funded state Delivery System Reform Incentive Payment programme to implement a hospital-wide initiative to reduce healthcare-associated infections (HAIs) and improve sepsis care.Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f4603bff9eddbe8be8f7c9cf18afa7
https://bmjopenquality.bmj.com/content/10/1/e001189.full

Sepsis at a Safety Net Hospital: Risk Factors Associated With 30-Day Readmission

Autor: Rosechelle M. Ruggiero, Mark Weinreich, Shelley Chang, Kim Styrvoky, Carlos E. Girod

Publikováno v: Journal of intensive care medicine. 34(11-12)

Background: Sepsis is a leading cause of hospitalization, and subsequent readmissions are frequent and costly. There is an expanding body of literature describing risk factors for readmissions in patients with sepsis. However, there are little data s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6820aebc5956b24e0c52a836b1ec0c7a
https://pubmed.ncbi.nlm.nih.gov/28820039

COPD

Autor: Carlos E. Girod, Talmadge E. King

Publikováno v: Chest. 128:3055-3064

Various reports have demonstrated the importance of small airway inflammation in the development of airflow limitation and progression of COPD. This hypothesis proposes that the pathogenesis of COPD mirrors a chronic inhalational dust-induced disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50a78d17da2b1b3ff0f63e5654f4a1aa
https://doi.org/10.1378/chest.128.4.3055

Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation

Autor: Kirk D. Jones, Carlos E. Girod, Paul J. Wolters, Brett M. Elicker, Bridget D. Stuart, Shwu Fan Ma, Fernando Torres, Harold R. Collard, Rekha Vij, Christine Kim Garcia, Joyce S. Lee, Megan S. Devine, Imre Noth, Craig S. Glazer, Julia Kozlitina, Vaidehi Kaza

Publikováno v: The Lancet. Respiratory medicine, vol 2, iss 7
Stuart, BD; Lee, JS; Kozlitina, J; Noth, I; Devine, MS; Glazer, CS; et al.(2014). Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. The Lancet Respiratory Medicine. doi: 10.1016/S2213-2600(14)70124-9. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2xn8k1sm

Background: Short telomere lengths are found in a subset of patients with idiopathic pulmonary fibrosis, but their clinical significance is unknown. Our aim was to investigate whether patients with various blood leucocyte telomere lengths had differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef350386e45c2200b3d113c93ee852
https://escholarship.org/uc/item/2xn8k1sm