Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Carlos E De Andrea"'
Autor:
Pedro Berraondo, Ignacio Melero, Miguel F Sanmamed, Carlos E De Andrea, María Campos, Iñaki Eguren-Santamaria, Eva Fernández de Piérola, Gracián Camps, Paula Martín-Muñoz, Doina Cuculescu, Inmaculada Aguilera-Buenosvinos, Inmaculada Rodríguez López, Rafael Salido-Vallejo, Raluca Alexandru, Laura Álvarez-Gigli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Immunodeficient mice engrafted with peripheral blood mononuclear cells (PBMCs) are models to study new cancer immunotherapy agents. However, this approach is associated with xenograft-versus-host disease (xGVHD), which starts early after P
Externí odkaz:
https://doaj.org/article/bf82f9c0cbf94be6a1a8d4e73fac748e
Autor:
Derek A Wainwright, Aurelio Hernández-Laín, Maria E Rodriguez-Ruiz, Olaya de Dios, Carlos E De Andrea, Angel Pérez-Nuñez, Diego Megías, M Angeles Ramírez-González, Irene Gómez-Soria, Berta Segura-Collar, Juliana Manosalva, Leticia Fernández-Rubio, Juan M Sepúlveda-Sánchez, Ricardo Gargini, Pilar Sánchez-Gómez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Activating and inhibitory receptors of natural killer (NK) cells such as NKp, NKG2, or CLEC are highly relevant to cold tumors including glioblastoma (GBM). Here, we aimed to characterize the expression of these receptors in GBM to gain in
Externí odkaz:
https://doaj.org/article/04d1b93182b748a8b6bc49cb908fda23
Autor:
Ignacio Melero, Alvaro Teijeira, Kurt A Schalper, Carlos E De Andrea, Alvaro Lopez Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Introduction The tissue immune microenvironment is associated with key aspects of tumor biology. The interaction between the immune system and cancer cells has predictive and prognostic potential across different tumor types. Spatially resolved tissu
Externí odkaz:
https://doaj.org/article/a78de50c324945a784d3648e434d4ee5
Autor:
Xiaowei Xu, Hao Wang, Michael Tetzlaff, James Ziai, Sabina Signoretti, Ashley Cimino-Mathews, Tricia Cottrell, Janis M Taube, Annikka Weissferdt, Richard A Scolyer, Pierre-Olivier Fiset, Jaime Rodriguez-Canales, Lynette M Sholl, Julie S Deutsch, Krista Chen, Carlos E de Andrea, Christine Orr, Salgado Roberto, Christian Schurch, Raja Seethala, Alexander S Baras
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/43e08721fce4413f885d76cce4d9f3a9
Autor:
Xavier Matias-Guiu, Ana Vivancos, Jordi Ponce, Ignacio Melero, Alena Gros, Josep María Piulats, Carlos E De Andrea, Maria Lozano-Rabella, Jara Palomero, August Vidal, Carla Panisello, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Despite the growing interest in immunotherapeutic interventions for endometrial cancer (EC), the prevalence, phenotype, specificity and prognostic value of tumor infiltrating lymphocytes (TILs) in this tumor type remains unclear.Methods To
Externí odkaz:
https://doaj.org/article/a6c6008c42274bd88a20c1988684f4bb
Autor:
Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design
Externí odkaz:
https://doaj.org/article/c301abd4787842b988871048df0364f6
Autor:
Pedro Berraondo, Ignacio Melero, Alvaro Teijeira, Carmen Molina, Marisol Quintero, Fernando Aranda, Maite Alvarez, Maria E Rodriguez-Ruiz, Xinyi Fan, Miguel F Sanmamed, Javier Glez-Vaz, Maria Villalba, Carlos E De Andrea, Myriam Fernandez-Sendin, Jose Gonzalez-Gomariz, Maria Carmen Ochoa, Wen H Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/9fb53e88bcd34935a6e8063f150d12bc
Autor:
Assunta Cirella, Elixabet Bolaños, Claudia Augusta Di Trani, Carlos E. de Andrea, Sandra Sánchez-Gregorio, Iñaki Etxeberria, Jose Gonzalez-Gomariz, Irene Olivera, Davide Brocco, Javier Glez-Vaz, Carlos Luri-Rey, Arantza Azpilikueta, Inmaculada Rodríguez, Myriam Fernandez-Sendín, Josune Egea, Iñaki Eguren, Miguel F. Sanmamed, Belen Palencia, Alvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Cancer Immunology Research. 11:184-198
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding IL12 and IL18. M
Autor:
Farshad Nassiri, Vikas Patil, Leeor S. Yefet, Olivia Singh, Jeff Liu, Rachel M. A. Dang, Takafumi N. Yamaguchi, Mariza Daras, Timothy F. Cloughesy, Howard Colman, Priya U. Kumthekar, Clark C. Chen, Robert Aiken, Morris D. Groves, Shirley S. Ong, Rohan Ramakrishna, Michael A. Vogelbaum, Simon Khagi, Thomas Kaley, Jason M. Melear, David M. Peereboom, Analiz Rodriguez, Maxim Yankelevich, Suresh G. Nair, Vinay K. Puduvalli, Kenneth Aldape, Andrew Gao, Álvaro López-Janeiro, Carlos E. de Andrea, Marta M. Alonso, Paul Boutros, Joan Robbins, Warren P. Mason, Adam M. Sonabend, Roger Stupp, Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Gelareh Zadeh
Publikováno v:
Nature Medicine.
Immune-mediated anti-tumoral responses, elicited by oncolytic viruses and augmented with checkpoint inhibition, may be an effective treatment approach for glioblastoma. Here in this multicenter phase 1/2 study we evaluated the combination of intratum
Autor:
Rafael Martínez-Monge, Fernando Lecanda, Ignacio Melero, Silvestre Vicent, Carlos E. de Andrea, María E. Rodríguez-Ruiz, Rubén Pío, Sandra Hervás-Stubbs, Dominique Heymann, Vratislav Strnad, Laura Guembe, Luis I. Ramos-García, Marta Santisteban, Carlos Ortiz de Solórzano, Xabier Morales, Sergio Ortiz-Espinosa, Daniel Ajona, Álvaro Teijeira, Susana Martínez-Canarias, Carolina Zandueta, Denis Cochonneau, Marta Abengózar-Muela, Antonio Pineda-Lucena, Elisabet Guruceaga, Juan Hinojosa, Alberto Pezonaga-Torres, Thomas Walle, Pablo Ruedas, Naiara Perurena, Karmele Valencia, Haritz Moreno, Borja Ruiz-Fernández de Córdoba
Locoregional failure (LRF) in patients with breast cancer post-surgery and post-irradiation is linked to a dismal prognosis. In a refined new model, we identified ectonucleotide pyrophosphatase/phosphodiesterase 1/CD203a (ENPP1) to be closely associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f26387c97cae4c74421dd25469470ce
https://doi.org/10.1158/2159-8290.c.6549629.v1
https://doi.org/10.1158/2159-8290.c.6549629.v1