Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Carlos E, de Andrea"'
Autor:
Pedro Berraondo, Ignacio Melero, Miguel F Sanmamed, Carlos E De Andrea, María Campos, Iñaki Eguren-Santamaria, Eva Fernández de Piérola, Gracián Camps, Paula Martín-Muñoz, Doina Cuculescu, Inmaculada Aguilera-Buenosvinos, Inmaculada Rodríguez López, Rafael Salido-Vallejo, Raluca Alexandru, Laura Álvarez-Gigli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Immunodeficient mice engrafted with peripheral blood mononuclear cells (PBMCs) are models to study new cancer immunotherapy agents. However, this approach is associated with xenograft-versus-host disease (xGVHD), which starts early after P
Externí odkaz:
https://doaj.org/article/bf82f9c0cbf94be6a1a8d4e73fac748e
Autor:
Derek A Wainwright, Aurelio Hernández-Laín, Maria E Rodriguez-Ruiz, Olaya de Dios, Carlos E De Andrea, Angel Pérez-Nuñez, Diego Megías, M Angeles Ramírez-González, Irene Gómez-Soria, Berta Segura-Collar, Juliana Manosalva, Leticia Fernández-Rubio, Juan M Sepúlveda-Sánchez, Ricardo Gargini, Pilar Sánchez-Gómez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Activating and inhibitory receptors of natural killer (NK) cells such as NKp, NKG2, or CLEC are highly relevant to cold tumors including glioblastoma (GBM). Here, we aimed to characterize the expression of these receptors in GBM to gain in
Externí odkaz:
https://doaj.org/article/04d1b93182b748a8b6bc49cb908fda23
Autor:
Ignacio Melero, Alvaro Teijeira, Kurt A Schalper, Carlos E De Andrea, Alvaro Lopez Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Introduction The tissue immune microenvironment is associated with key aspects of tumor biology. The interaction between the immune system and cancer cells has predictive and prognostic potential across different tumor types. Spatially resolved tissu
Externí odkaz:
https://doaj.org/article/a78de50c324945a784d3648e434d4ee5
Autor:
Daniel Jiménez-Sánchez, Álvaro López-Janeiro, María Villalba-Esparza, Mikel Ariz, Ece Kadioglu, Ivan Masetto, Virginie Goubert, Maria D. Lozano, Ignacio Melero, David Hardisson, Carlos Ortiz-de-Solórzano, Carlos E. de Andrea
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Predicting recurrence in low-grade, early-stage endometrial cancer (EC) is both challenging and clinically relevant. We present a weakly-supervised deep learning framework, NaroNet, that can learn, without manual expert annotation, the compl
Externí odkaz:
https://doaj.org/article/a012ff9099484386aca7d1ea74f03ffa
Autor:
Xiaowei Xu, Hao Wang, Michael Tetzlaff, James Ziai, Sabina Signoretti, Ashley Cimino-Mathews, Tricia Cottrell, Janis M Taube, Annikka Weissferdt, Richard A Scolyer, Pierre-Olivier Fiset, Jaime Rodriguez-Canales, Lynette M Sholl, Julie S Deutsch, Krista Chen, Carlos E de Andrea, Christine Orr, Salgado Roberto, Christian Schurch, Raja Seethala, Alexander S Baras
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/43e08721fce4413f885d76cce4d9f3a9
Autor:
Amy R. Cross, Carlos E. de Andrea, María Villalba-Esparza, Manuel F. Landecho, Lucia Cerundolo, Praveen Weeratunga, Rachel E. Etherington, Laura Denney, Graham Ogg, Ling-Pei Ho, Ian S.D. Roberts, Joanna Hester, Paul Klenerman, Ignacio Melero, Stephen N. Sansom, Fadi Issa
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Severe lung damage resulting from COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways, and genes present across the
Externí odkaz:
https://doaj.org/article/7096c4d58dbb4565a8572524c105e1a2
Autor:
Xavier Matias-Guiu, Ana Vivancos, Jordi Ponce, Ignacio Melero, Alena Gros, Josep María Piulats, Carlos E De Andrea, Maria Lozano-Rabella, Jara Palomero, August Vidal, Carla Panisello, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Despite the growing interest in immunotherapeutic interventions for endometrial cancer (EC), the prevalence, phenotype, specificity and prognostic value of tumor infiltrating lymphocytes (TILs) in this tumor type remains unclear.Methods To
Externí odkaz:
https://doaj.org/article/a6c6008c42274bd88a20c1988684f4bb
Autor:
Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design
Externí odkaz:
https://doaj.org/article/c301abd4787842b988871048df0364f6
Autor:
Virginia Laspidea, Montserrat Puigdelloses, Sara Labiano, Lucía Marrodán, Marc Garcia-Moure, Marta Zalacain, Marisol Gonzalez-Huarriz, Naiara Martínez-Vélez, Iker Ausejo-Mauleon, Daniel de la Nava, Guillermo Herrador-Cañete, Javier Marco-Sanz, Elisabeth Guruceaga, Carlos E. de Andrea, María Villalba, Oren Becher, Massimo Squatrito, Verónica Matía, Jaime Gállego Pérez-Larraya, Ana Patiño-García, Sumit Gupta, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors, and patient survival has not changed despite many therapeutic efforts, emphasizing the urgent need for effective treatments. Here, we evaluated the anti-DIPG effect of t
Externí odkaz:
https://doaj.org/article/ce5f44e54382422bab0de99c10b63d55
Autor:
Pedro Berraondo, Ignacio Melero, Alvaro Teijeira, Carmen Molina, Marisol Quintero, Fernando Aranda, Maite Alvarez, Maria E Rodriguez-Ruiz, Xinyi Fan, Miguel F Sanmamed, Javier Glez-Vaz, Maria Villalba, Carlos E De Andrea, Myriam Fernandez-Sendin, Jose Gonzalez-Gomariz, Maria Carmen Ochoa, Wen H Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/9fb53e88bcd34935a6e8063f150d12bc