Loss of 5′-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness

Autor: Weder Pereira de Menezes, Viviane Aline Oliveira Silva, Izabela Natália Faria Gomes, Marcela Nunes Rosa, Maria Luisa Corcoll Spina, Adriana Cruvinel Carloni, Ana Laura Vieira Alves, Matias Melendez, Gisele Caravina Almeida, Luciane Sussuchi da Silva, Carlos Clara, Isabela Werneck da Cunha, Glaucia Noeli Maroso Hajj, Chris Jones, Lucas Tadeu Bidinotto, Rui Manuel Reis

Publikováno v: Cells, Vol 9, Iss 2, p 492 (2020)

The 5’-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. MTAP deletion is a frequent event in a wide variety of human cancers; however, its biological role in tumorigenesis remains unclear. The purpose of this

Externí odkaz: https://doaj.org/article/ca517d8f93004ddca5f095d3f8954f4c

Low-grade astrocytoma: surgical outcomes in eloquent versus non-eloquent brain areas Astrocitoma de baixo grau: resultado cirúrgico em área eloquente versus não eloquente

Autor: André de Macedo Bianco, Flavio Key Miura, Carlos Clara, Jose Reynaldo W. Almeida, Clemar Correa da Silva, Manoel Jacobsen Teixeira, Suely K. Nagahashi Marie

Publikováno v: Arquivos de Neuro-Psiquiatria, Iss ahead, p 0 (2012)

A retrospective study of 81 patients with low-grade astrocytoma (LGA) comparing the efficacy of aggressive versus less aggressive surgery in eloquent and non-eloquent brain areas was conducted. Extent of surgical resection was analyzed to assess over

Externí odkaz: https://doaj.org/article/137aa0e91fc4490d975cbeb4a28f0f4b

AVALIAÇÃO DA NUTRIÇÃO ENTERAL EM UNIDADE DE TERAPIA INTENSIVA.

Autor: Therrier, Sterline¹ sterlinetherrier@yahoo.fr, Marize Carlos, Clara², Fernandes Costa, Raquel³, Rezende Simino, Giovana Paula⁴, Guimarães Barbosa, Jaqueline Almeida⁴

Publikováno v: Revista Baiana de Enfermagem. 2021, Vol. 35, p1-10. 10p.

WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma

Autor: Manuel Melo Pires, Marta Pojo, Emmanuel Chautard, Joana Isabel Martins Cosme Vieira Castro, Sandro Queirós, Eduarda P. Martins, Ricardo Taipa, Carlos Clara, Fernando Pardal, Bruno M. Costa, Rui Manuel Reis, Céline S. Gonçalves, Claudia C. Faria, Nuno Sousa, Afonso A. Pinto, Carlos Custódia

Publikováno v: Theranostics
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação

Glioblastoma (GBM) is a universally fatal brain cancer, for which novel therapies targeting specific underlying oncogenic events are urgently needed. While the WNT pathway has been shown to be frequently activated in GBM, constituting a potential the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82714015a07c710b8742a382c757b197
http://europepmc.org/articles/PMC6160775

OTX1 and OTX2 Genes in Medulloblastoma

Autor: Roseli da Silva, Benedito Pereira, Valeria Marques Figueira Muoio, Carlos Clara, Suely Kn Marie, Hamilton Matushita, Miyuki Uno, Sueli Mieko Oba-Shinjo

Publikováno v: World neurosurgery. 127

Objective To study the prevalence of OTX1 and OTX2 gene expression in 60 medulloblastoma specimen samples and to establish correlations between gene expression and clinical and histopathological aspects. Methods We performed a retrospective analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710448ce6364cdff98770ea5be9f704f
https://pubmed.ncbi.nlm.nih.gov/31421436