Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Carlos Carretero Puche"'
Autor:
Beatriz Soldevilla, Alberto Lens‐Pardo, Paula Espinosa‐Olarte, Carlos Carretero‐Puche, Sonia Molina‐Pinelo, Carlos Robles, Marta Benavent, Lourdes Gomez‐Izquierdo, Marta Fierro‐Fernández, Patricia Morales‐Burgo, Paula Jimenez‐Fonseca, Beatriz Anton‐Pascual, Yolanda Rodriguez‐Gil, Ana Teijo‐Quintans, Anna La Salvia, Beatriz Rubio‐Cuesta, Maria C. Riesco‐Martínez, Rocio Garcia‐Carbonero
Publikováno v:
Molecular Oncology, Vol 17, Iss 4, Pp 582-597 (2023)
Neuroendocrine neoplasms (NENs) are mutationally quiet (low number of mutations/Mb), and epigenetic mechanisms drive their development and progression. We aimed at comprehensively characterising the microRNA (miRNA) profile of NENs, and exploring dow
Externí odkaz:
https://doaj.org/article/96f622ea83a04182b9b9cbef9fb1d2ac
Autor:
Coral Fustero-Torre, María José Jiménez-Santos, Santiago García-Martín, Carlos Carretero-Puche, Luis García-Jimeno, Vadym Ivanchuk, Tomás Di Domenico, Gonzalo Gómez-López, Fátima Al-Shahrour
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract We present Beyondcell, a computational methodology for identifying tumour cell subpopulations with distinct drug responses in single-cell RNA-seq data and proposing cancer-specific treatments. Our method calculates an enrichment score in a c
Externí odkaz:
https://doaj.org/article/a8f0969e9dc24d2989a07cfd172f5edf
Autor:
Rocio Garcia-Carbonero, Beatriz Anton-Pascual, Andrea Modrego, Maria del Carmen Riesco-Martinez, Alberto Lens-Pardo, Carlos Carretero-Puche, Beatriz Rubio-Cuesta, Beatriz Soldevilla
Publikováno v:
Endocrine Reviews.
Poorly differentiated gastroenteropancreatic neuroendocrine carcinomas are aggressive neoplasms of challenging clinical management. A small proportion of patients with early-stage disease may achieve long-term survival, but the majority of patients p
Autor:
null Beatriz Soldevilla, null Alberto Lens‐Pardo, null Paula Espinosa‐Olarte, null Carlos Carretero‐Puche, null Sonia Molina‐Pinelo, null Carlos Robles, null Marta Benavent, null Lourdes Gomez‐Izquierdo, null Marta Fierro‐Fernández, null Patricia Morales‐Burgo, null Paula Jimenez‐Fonseca, null Beatriz Anton‐Pascual, null Yolanda Rodriguez‐Gil, null Ana Teijo‐Quintans, null Anna La Salvia, null Beatriz Rubio‐Cuesta, null Maria C Riesco‐Martínez, null Rocio Garcia‐Carbonero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8359ac21c24eb52846b8a77c4fe5705
https://doi.org/10.1002/1878-0261.13393/v2/response1
https://doi.org/10.1002/1878-0261.13393/v2/response1
Autor:
Anna La Salvia, Beatriz Gil-Calderón, Beatriz Rubio-Cuesta, Ángeles López-López, Rocio Garcia-Carbonero, Raúl Rincón, Carlos Carretero-Puche, Beatriz Soldevilla, Alberto Lens-Pardo, P. Espinosa-Olarte, Coral Barbas, Maria C Riesco-Martinez, Ángeles López-Gonzálvez, Jacinto Sarmentero
Publikováno v:
Cancers, Vol 13, Iss 2634, p 2634 (2021)
Cancers
Volume 13
Issue 11
Cancers
Volume 13
Issue 11
Simple Summary Metabolic flexibility is one of the key hallmarks of cancer and metabolites are the final products of this adaptation, reflecting the aberrant changes of tumors. However, the metabolic plasticity of each cancer type is still unknown, a
Autor:
Gonzalo Gómez-López, Carlos Carretero-Puche, Santiago García-Martín, Fatima Al-Shahrour, Rocio Garcia-Carbonero
Publikováno v:
Expert Review of Precision Medicine and Drug Development. 5:115-117
The last few years have witnessed the emergence of personalized precision medicine (PPM), a novel approach to improve clinical decisions, integrating individual multi-omic profiles, and heterogeneo...
Autor:
Beatriz Rubio Cuesta, Beatriz Gil Calderón, Patricia LLamas Granda, Jacinto Sarmentero, Carlos Carretero Puche, María del Carmen Riesco, Rocío García Carbonero, Beatriz Soldevilla
Publikováno v:
Cancer Research. 82:355-355
Oncogenic mutations in B-type Raf Kinase (BRAF) (particularly V600E) are present in 7-10% of metastatic colorectal cancer (mCRC), conferring resistance to conventional therapies and a poor prognosis. Src Family Kinases (SFKs) play a relevant role in
Autor:
Carlos Carretero Puche, Beatriz Soldevilla, Beatriz Gil, Anna La Salvia, Alberto Lens-Pardo, Paula Espinosa, Beatriz Anton-Pascual, Gonzalo Gómez-López, Fátima Al-Shahrour, Rocío García-Carbonero
Publikováno v:
Cancer Research. 82:2289-2289
Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with a wide anatomical distribution and different clinical behaviors that share common “neuro” and “endocrine” properties. They are classified in well differentiated G1, G2 a
Autor:
Gonzalo Gómez-López, Coral Fustero-Torre, Santiago García-Martín, García-Jimeno L, Carlos Carretero-Puche, Fatima Al-Shahrour, Di Domenico T, María José Jiménez-Santos
We present Beyondcell (https://gitlab.com/bu_cnio/beyondcell/), a computational methodology for identifying tumour cell subpopulations with distinct drug responses in single-cell RNA-seq data and proposing cancer-specific treatments. Our method calcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e3a8d41cb8daa0cc96ec37e6d36b307
https://doi.org/10.1101/2021.04.08.438954
https://doi.org/10.1101/2021.04.08.438954
Autor:
Gonzalo Gómez-López, Santiago García-Martín, Daniel Gonzalez-Peña, Miguel Reboiro-Jato, Hugo López-Fernández, Kevin Troulé, Pedro Carmona-Sáez, Guillermo Martín-Serrano, Carlos Carretero-Puche, Jordi Martorell-Marugán, Fatima Al-Shahrour
Motivation Drug immunomodulation modifies the response of the immune system and can be therapeutically exploited in pathologies such as cancer and autoimmune diseases. Results DREIMT is a new hypothesis-generation web tool, which performs drug priori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a7c706b13eef0777d2f07fed45f2c8
https://academic.oup.com/bioinformatics/article-pdf/37/4/578/37757681/btaa727.pdf
https://academic.oup.com/bioinformatics/article-pdf/37/4/578/37757681/btaa727.pdf