Data from Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Autor: Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi

Purpose:Tumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade. We conducted a prospective multicenter phase II trial of intratumoral plasmid IL-12 (tavokinogene te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd2c239e09f2d5a2524c8e57f19d8f4
https://doi.org/10.1158/1078-0432.c.6529707.v1

Supplementary Figure Legends from Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Autor: Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi

Supplementary Figure Legends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25d0cab47894d2b34b9067e043e1f48c
https://doi.org/10.1158/1078-0432.22477611.v1

Table S1 from Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Autor: Adil I. Daud, Michael D. Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, Sharron Gargosky, Shailender Bhatia, Carmen Ballesteros-Merino, Carlos Bifulco, Lauren P. Levine, Christopher Garris, Sean P. Arlauckas, Mikael J. Pittet, Lawrence Fong, Murray Francisco, Arielle Oglesby, Donna Bannavong, David A. Canton, Reneta Hermiz, Erica Browning, Robert Pierce, Mai Le, Katy K. Tsai, Christopher G. Twitty, Alain P. Algazi

Fluorescence-conjugated antibody used for flow cytometry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8d94d6e88de77d925c2a23a7e19a74
https://doi.org/10.1158/1078-0432.22477608

Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Autor: Mai Le, Shailender Bhatia, Carmen Ballesteros-Merino, Adil Daud, Murray Francisco, Christopher G. Twitty, Erica Browning, Reneta Hermiz, Mikael J. Pittet, Arielle Oglesby, Sharron Gargosky, Katy K. Tsai, Christopher Garris, Lawrence Fong, Michael Rosenblum, Bernard A. Fox, Robert H.I. Andtbacka, David A. Canton, Alain Algazi, Carlos Bifulco, Lauren P. Levine, Donna Bannavong, Sean P. Arlauckas, Robert H. Pierce

Publikováno v: BASE-Bielefeld Academic Search Engine
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 12
Clin Cancer Res
Clinical Cancer Research, Vol. 26, No 12 (2020) pp. 2827-2837

Purpose: Tumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade. We conducted a prospective multicenter phase II trial of intratumoral plasmid IL-12 (tavokinogene t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d86693cc71daf5a3684a1122cd1bce
https://escholarship.org/uc/item/59t2b8v3