Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Carlos B. Duarte"'
Autor:
Ivan L. Salazar, Ana S. T. Lourenço, Bruno Manadas, Inês Baldeiras, Cláudia Ferreira, Anabela Claro Teixeira, Vera M. Mendes, Ana Margarida Novo, Rita Machado, Sónia Batista, Maria do Carmo Macário, Mário Grãos, Lívia Sousa, Maria João Saraiva, Alberto A. C. C. Pais, Carlos B. Duarte
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-23 (2022)
Abstract Background Multiple sclerosis is an inflammatory and degenerative disease of the central nervous system (CNS) characterized by demyelination and concomitant axonal loss. The lack of a single specific test, and the similarity to other inflamm
Externí odkaz:
https://doaj.org/article/6b2bf2bed6834383ba5bb3e0a3f52ea9
Autor:
Miranda Mele, Ricardo Vieira, Bárbara Correia, Pasqualino De Luca, Filipe V. Duarte, Paulo S. Pinheiro, Carlos B. Duarte
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cell culture models are important tools to study epileptogenesis mechanisms. The aim of this work was to characterize the spontaneous and synchronized rhythmic activity developed by cultured hippocampal neurons after transient incubation in
Externí odkaz:
https://doaj.org/article/3e6dc83da6f64a38871222111d585ee4
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the central nervous system (CNS). Regulation of GABAAR trafficking and the control of their surface expression play important roles in the modulation of the streng
Externí odkaz:
https://doaj.org/article/0fc23c7867a1441596d39ee226e53290
Autor:
Marta M. Vieira, Jeannette Schmidt, Joana S. Ferreira, Kevin She, Shinichiro Oku, Miranda Mele, Armanda E. Santos, Carlos B. Duarte, Ann Marie Craig, Ana Luísa Carvalho
Publikováno v:
Neurobiology of Disease, Vol 89, Iss , Pp 223-234 (2016)
Global cerebral ischemia induces selective degeneration of specific subsets of neurons throughout the brain, particularly in the hippocampus and cortex. One of the major hallmarks of cerebral ischemia is excitotoxicity, characterized by overactivatio
Externí odkaz:
https://doaj.org/article/7d7460193e4a4df9af34319a6e70f012
Autor:
Wibke Singer, Marie Manthey, Rama Panford-Walsh, Lucas Matt, Hyun-Soon Geisler, Eleonora Passeri, Gabriele Baj, Enrico Tongiorgi, Graciano Leal, Carlos B. Duarte, Ivan L. Salazar, Philipp Eckert, Karin Rohbock, Jing Hu, Jörg Strotmann, Peter Ruth, Ulrike Zimmermann, Lukas Rüttiger, Thomas Ott, Thomas Schimmang, Marlies Knipper
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their differential transcription translates activity changes into long-lasting network chang
Externí odkaz:
https://doaj.org/article/3cb0c2e2e5294877a4c2b7fa0e4a4b48
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 220-232 (2014)
Cerebral ischemia is characterized by an early disruption of GABAergic neurotransmission contributing to an imbalance of the excitatory/inhibitory equilibrium and neuronal death, but the molecular mechanisms involved are not fully understood. Here we
Externí odkaz:
https://doaj.org/article/b665a26886ee4d448e102070dff635cd
Autor:
Andrea C. Lobo, João R. Gomes, Tatiana Catarino, Miranda Mele, Pedro Fernandez, Ana R. Inácio, Ben A. Bahr, Armanda E. Santos, Tadeusz Wieloch, Ana Luísa Carvalho, Carlos B. Duarte
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 3, Pp 292-303 (2011)
Glutamate is loaded into synaptic vesicles by vesicular glutamate transporters (VGLUTs), and alterations in the transporters expression directly regulate neurotransmitter release. We investigated changes in VGLUT1 and VGLUT2 protein levels after isch
Externí odkaz:
https://doaj.org/article/4dada7c13056462ba5e4212bced3e21c
Publikováno v:
Mediators of Inflammation, Vol 2005, Iss 3, Pp 131-138 (2005)
We used a mouse fetal skin dendritic cell line (FSDC) to study the effect of the strong allergen 2,4-dinitrofluorobenzene (DNFB) on interleukin (IL)-1β release and IL-1β receptor immunoreactivity. Stimulation with DNFB (30 minutes) increased IL-1β
Externí odkaz:
https://doaj.org/article/11a50973bd28481cb11538b8441c7381
Autor:
Ana Luísa Vital, Margarida Gonçalo, M. Teresa Cruz, Américo Figueiredo, Carlos B. Duarte, M. Celeste Lopes
Publikováno v:
Mediators of Inflammation, Vol 12, Iss 2, Pp 71-78 (2003)
Aims: Nitric oxide (NO) has been increasingly implicated in inflammatory skin diseases, namely in allergic contact dermatitis. In this work, we investigated the effect of dexamethasone on NO production induced by the epidermal cytokine granulocyte-ma
Externí odkaz:
https://doaj.org/article/4ebf0339179e4cf78a6c5ca025fdcb97
Publikováno v:
Mediators of Inflammation, Vol 10, Iss 5, Pp 245-251 (2001)
Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory action
Externí odkaz:
https://doaj.org/article/5317d21a2ca946ee883bddbed2061d5c