Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Carlos B Mantilla"'
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 38, Iss 5 (2020)
Introduction: The diaphragm muscle (DIAm) contains a mixed motor units population, with FInt and FF units (comprising type IIx and/or IIb muscle fibers) vulnerable to sarcopenia - age-associated reductions of specific force and cross-sectional area (
Externí odkaz:
https://doaj.org/article/76e7ba1a518b45f3a38a30af4b531726
Autor:
Sepideh Jahanian, Miguel Pareja-Cajiao, Heather M. Gransee, Gary C. Sieck, Carlos B. Mantilla
Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112483- (2024)
Autophagy is a ubiquitous process through which damaged cytoplasmic structures are recycled and degraded within cells. Aging can affect autophagy regulation in different steps leading to the accumulation of damaged organelles and proteins, which can
Externí odkaz:
https://doaj.org/article/399e59a7720a422690c405e48ca43646
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64755 (2013)
Progressive recovery of rhythmic phrenic activity occurs over time after a spinal cord hemisection involving unilateral transection of anterolateral funiculi at C2 (SH). Brain-derived neurotrophic factor (BDNF) acting through its full-length tropomyo
Externí odkaz:
https://doaj.org/article/7eb4c561b14e40c98f53e5da2e271e9c
Publikováno v:
Physiological Reports, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Cervical spinal cord injury impacts ventilatory and non‐ventilatory functions of the diaphragm muscle (DIAm) and contributes to clinical morbidity and mortality in the afflicted population. Periodically, integrated brainstem neural circuit
Externí odkaz:
https://doaj.org/article/9d3dec18a307486880a1c75185179145
Autor:
Maria A. Gonzalez Porras, Heather M. Gransee, Travis T. Denton, Dunxin Shen, Kevin L. Webb, C. Jeffrey Brinker, Achraf Noureddine, Gary C. Sieck, Carlos B. Mantilla
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including motor neuron disorders. Motor neuron targeted upregulation of autophagy may serve
Externí odkaz:
https://doaj.org/article/619ee3b19e7e4d9793f0aae67eed638a
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The neuromuscular junction (NMJ) mediates neural control of skeletal muscle fibers. Neurotrophic signaling, specifically brain derived neurotrophic factor (BDNF) acting through its high-affinity tropomyosin related kinase B (TrkB) receptor is known t
Externí odkaz:
https://doaj.org/article/e32bda53bc914dac943bbdf4645eb6ac
Publikováno v:
Journal of Applied Physiology. 134:1332-1340
Type S and FR motor units, comprising smaller phrenic motor neurons (PhMNs) are regularly activated to perform indefatigable ventilatory requirements. By contrast, type FF motor units, comprising larger PhMNs, are infrequently activated to perform ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43798ffe4e3bb8658d0c483996529a43
https://doi.org/10.1152/japplphysiol.00021.2023
https://doi.org/10.1152/japplphysiol.00021.2023
Autor:
Carlos B. Mantilla, Leonid G. Ermilov, Sarah M. Greising, Heather M. Gransee, Wen-Zhi Zhan, Gary C. Sieck
Publikováno v:
Journal of Neurophysiology. 129:781-792
Neurotrophin brain-derived neurotrophic factor (BDNF) enhances neuromuscular transmission via activation of tropomyosin-related kinase receptor B (TrkB). Rat phrenic nerve-diaphragm muscle preparations were used to determine the rapid effect of BDNF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9f2895d851b814f75d4e7264e75f0b
https://doi.org/10.1152/jn.00015.2023
https://doi.org/10.1152/jn.00015.2023
Autor:
Alyssa D. Brown, Matthew J. Fogarty, Leah A. Davis, Debanjali Dasgupta, Carlos B. Mantilla, Gary C. Sieck
Publikováno v:
J Appl Physiol (1985)
Type I and IIa diaphragm muscle (DIAm) fibers comprise slow and fast fatigue-resistant motor units that are recruited to accomplish breathing and thus have a high duty cycle. In contrast, type IIx/IIb fibers comprise more fatigable fast motor units t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96229cbf15785309d92bf06a3f3b43cf
https://pubmed.ncbi.nlm.nih.gov/35678745
https://pubmed.ncbi.nlm.nih.gov/35678745
Autor:
Alexander S. McLawhorn, Sang Jo Kim, Jacques T. YaDeau, Christopher L. Wu, Rosemary Hogg, George Go, Ellen M. Soffin, Janis Bekeris, Carlos B. Mantilla, Sandra L. Kopp, Paul Kessler, Peter Gerner, Rebecca L. Johnson, Jiabin Liu, Douglas S Wetmore, Jashvant Poeran, Philip Peng, Rie Goto, Eriphili Argyra, Mary J. Hargett, Pamela Wendel, Nigel E. Sharrock, Crispiana Cozowicz, Patricia Lavand'homme, Lila Baaklini, Effrossyni Gina Votta-Velis, Lazaros Poultsides, Eric C. Sun, Javad Parvizi, Eric S. Schwenk, Lukas Pichler, Michael John Barrington, Catherine H. MacLean, Alain Borgeat, Jose De Andres, Alejandro Gonzalez Della Valle, Stavros G. Memtsoudis, Kariem El-Boghdadly, Nabil M. Elkassabany, Eugene R. Viscusi, Ottokar Stundner, Henrik Kehlet, Philippe Gautier, Bradley H. Lee, Genewoo Hong, Michael L. Parks, Enrique A. Goytizolo, Brian D. Sites, Dan McIsaac, Dace Bekere, Vassilis Athanassoglou, Edward R. Mariano, Joseph M. Neal, Zhenggang Guo, Alan J. R. Macfarlane, Bridget Jivanelli, Mark Brouillette
Publikováno v:
Regional Anesthesia & Pain Medicine. 46:971-985
BackgroundEvidence-based international expert consensus regarding the impact of peripheral nerve block (PNB) use in total hip/knee arthroplasty surgery.MethodsA systematic review and meta-analysis: randomized controlled and observational studies inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0dff4d7cb5cecc9097f4c5bc116aac0
https://doi.org/10.1136/rapm-2021-102750
https://doi.org/10.1136/rapm-2021-102750