Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Carlos B Duarte"'
Autor:
Ivan L. Salazar, Ana S. T. Lourenço, Bruno Manadas, Inês Baldeiras, Cláudia Ferreira, Anabela Claro Teixeira, Vera M. Mendes, Ana Margarida Novo, Rita Machado, Sónia Batista, Maria do Carmo Macário, Mário Grãos, Lívia Sousa, Maria João Saraiva, Alberto A. C. C. Pais, Carlos B. Duarte
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-23 (2022)
Abstract Background Multiple sclerosis is an inflammatory and degenerative disease of the central nervous system (CNS) characterized by demyelination and concomitant axonal loss. The lack of a single specific test, and the similarity to other inflamm
Externí odkaz:
https://doaj.org/article/6b2bf2bed6834383ba5bb3e0a3f52ea9
Autor:
Miranda Mele, Ricardo Vieira, Bárbara Correia, Pasqualino De Luca, Filipe V. Duarte, Paulo S. Pinheiro, Carlos B. Duarte
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cell culture models are important tools to study epileptogenesis mechanisms. The aim of this work was to characterize the spontaneous and synchronized rhythmic activity developed by cultured hippocampal neurons after transient incubation in
Externí odkaz:
https://doaj.org/article/3e6dc83da6f64a38871222111d585ee4
Autor:
Inês Caramelo, Margarida Coelho, Miguel Rosado, Carla M. P. Cardoso, Alexandra Dinis, Carlos B. Duarte, Mário Grãos, Bruno Manadas
Publikováno v:
World Journal of Pediatrics. 19:505-548
Background Current diagnostic criteria for hypoxic–ischemic encephalopathy in the early hours lack objective measurement tools. Therefore, this systematic review aims to identify putative molecules that can be used in diagnosis in daily clinical pr
Publikováno v:
Molecular Neurobiology. 60:3507-3521
Learned fear is orchestrated by a brain fear network that comprises the amygdala, hippocampus and the medial prefrontal cortex. Synaptic plasticity within this network is critical for the formation of proper fear memories. Known for their role in the
Autor:
Elisa Corti, Carlos B. Duarte
Publikováno v:
Biochemical Society Transactions. 51:315-330
AMPA-type receptors for the neurotransmitter glutamate are very dynamic entities, and changes in their synaptic abundance underlie different forms of synaptic plasticity, including long-term synaptic potentiation (LTP), long-term depression (LTD) and
Publikováno v:
Journal of Molecular Neuroscience. 72:1500-1515
Epilepsy is a neurological disease characterized by abnormal or synchronous brain activity causing seizures, which may produce convulsions, minor physical signs, or a combination of symptoms. These disorders affect approximately 65 million people wor
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the central nervous system (CNS). Regulation of GABAAR trafficking and the control of their surface expression play important roles in the modulation of the streng
Externí odkaz:
https://doaj.org/article/0fc23c7867a1441596d39ee226e53290
Autor:
Marta M. Vieira, Jeannette Schmidt, Joana S. Ferreira, Kevin She, Shinichiro Oku, Miranda Mele, Armanda E. Santos, Carlos B. Duarte, Ann Marie Craig, Ana Luísa Carvalho
Publikováno v:
Neurobiology of Disease, Vol 89, Iss , Pp 223-234 (2016)
Global cerebral ischemia induces selective degeneration of specific subsets of neurons throughout the brain, particularly in the hippocampus and cortex. One of the major hallmarks of cerebral ischemia is excitotoxicity, characterized by overactivatio
Externí odkaz:
https://doaj.org/article/7d7460193e4a4df9af34319a6e70f012
Autor:
Sara R. Oliveira, João Castelhano, José Sereno, Lorena Petrella, Miguel Castelo-Branco, Helena L. A. Vieira, Carlos B. Duarte
Although stroke is the main cause of brain damage worldwide, stroke therapies are based on blood reperfusion and do not target cerebral parenchyma. Ischemic stroke (representing 87% of all strokes) causes cerebral damage due to oxygen and tissue ener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09b9777f366f511b09ec175f015461d7
https://doi.org/10.1101/2022.11.10.515956
https://doi.org/10.1101/2022.11.10.515956
Autor:
Wibke Singer, Marie Manthey, Rama Panford-Walsh, Lucas Matt, Hyun-Soon Geisler, Eleonora Passeri, Gabriele Baj, Enrico Tongiorgi, Graciano Leal, Carlos B. Duarte, Ivan L. Salazar, Philipp Eckert, Karin Rohbock, Jing Hu, Jörg Strotmann, Peter Ruth, Ulrike Zimmermann, Lukas Rüttiger, Thomas Ott, Thomas Schimmang, Marlies Knipper
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their differential transcription translates activity changes into long-lasting network chang
Externí odkaz:
https://doaj.org/article/3cb0c2e2e5294877a4c2b7fa0e4a4b48