Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Carlos Antonio Trindade da Silva"'
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Soluble epoxide hydrolase inhibition enhances Specialized Pro-resolving Lipid Mediator production and promotes macrophage plasticity
Autor: Henrique B, Abdalla, Carla, Alvarez, Yu-Chiao, Wu, Paola, Rojas, Bruce D, Hammock, Krishna R, Maddipati, Carlos Antonio, Trindade-da-Silva, Mariana Q S, Soares, Juliana T, Clemente-Napimoga, Alpdogan, Kantarci, Marcelo H, Napimoga, Thomas E, Van Dyke
Publikováno v: British journal of pharmacology.
Epoxyeicosatrienoic acids (EETs) and other epoxy fatty acids (EpFA) are lipid mediators that are rapidly inactivated by soluble epoxide hydrolase. Uncontrolled and chronic inflammatory disorders fail to sufficiently activate endogenous regulatory pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7ca77ed6d704b6b86f4798cb08f628b
https://pubmed.ncbi.nlm.nih.gov/36508312
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3
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications
Autor: Carlos Antonio Trindade da Silva, Juliana Trindade Clemente-Napimoga, Henrique Ballassini Abdalla, Rosanna Tarkany Basting, Marcelo Henrique Napimoga
Publikováno v: Expert review of clinical pharmacology. 15(3)
Pain is a multidimensional experience involving the biological, psychological, and social dimensions of each individual. Particularly, the biological aspects of pain conditions are a response of the neuroimmunology system and the control of painful c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b6a97d9a240fcb9773f60fea4faa21
https://pubmed.ncbi.nlm.nih.gov/35481412
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4
The Modulatory Effect of 15d-PGJ2 in Dendritic Cells
Autor: Antonio José de Pinho, Thais S. Farnesi-de-Assunção, Marcelo Henrique Napimoga, Vanessa Carregaro, Carlos Antonio Trindade da Silva
Publikováno v: Nuclear Receptor Research, Vol 1, Pp 1-7 (2014)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The PPAR-γ ligands, in special 15-deoxy-Δ12,14-PGJ2 (15d-PGJ2), negatively regulate the cells of innate and adaptative immune system and present excellent results in different models of inflammatory diseases. These findings support the notion that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2b85a9ffef57e3f15a29d520088041
http://www.kenzpub.com/journals/nurr/2014/101083/
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5
Interleukin-6, tumor necrosis factor-α, C-reactive protein, and hematological parameters in experimental periodontal disease after β-adrenergic blockade
Autor: Carlos Antonio Trindade da Silva, Camila Botelho Miguel, Carlo José Freire Oliveira, Carlos Ueira Vieira, Juliana Trindade Clemente-Napimoga, Wellington Francisco Rodrigues, Marcelo Henrique Napimoga, Javier Emilio Lazo-Chica
Publikováno v: Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology, Vol 23, Iss 6, Pp 511-516 (2019)
Background: Changes in the levels of C-reactive protein (CRP), tumor necrosis factor α (TNF-α), and interleukin 6 (IL-6) observed during periodontal disease were linked with vascular manifestations. Recent studies showed that the beta-blocker propr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880766c3b892dcf287fadfd6329b3f15
https://doi.org/10.4103/jisp.jisp_77_19
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6
Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis
Autor: Kin Sing Stephen Lee, Marcelo Henrique Napimoga, Bruce D. Hammock, Fawaz G. Haj, Donald A. Bruun, Bora Inceoglu, Carlos Antonio Trindade-da-Silva, Ahmed Bettaieb, Sumanta Kumar Goswami, Carlos Ueira-Vieira
Publikováno v: The Journal of pharmacology and experimental therapeutics, vol 361, iss 3
Epoxyeicosatrienoic acids (EETs), metabolites of arachidonic acid derived from the cytochrome P450 enzymes, are mainly metabolized by soluble epoxide hydrolase (sEH) to their corresponding diols. EETs but not their diols, have anti-inflammatory prope
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0f209da056337cf74807d8346053e1
https://pubmed.ncbi.nlm.nih.gov/28356494
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7
O Uso terapêutico de mediadores anti-inflamatórios da via do ácido araquidônico
Autor: Carlos Antonio Trindade da Silva
Publikováno v: Repositório Institucional da UFU
Universidade Federal de Uberlândia (UFU)
instacron:UFU
O ácido araquidônico (AA) é precursor na formação dos eicosanoides, que são mediadores lipídicos com uma série de funções na fisiologia e patologia humana. A maioria dos eicosanoides atuam como mediadores pró-inflamatórios e contribuem pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20982c2d04d6ce59b126c9d09f060f98
https://repositorio.ufu.br/handle/123456789/17681
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8
PPAR-γ agonists, mainly 15d-PGJ2, reduce eosinophil recruitment following allergen challenge
Autor: Fernando Q. Cunha, Claudiney F. Alves, Jhony Robison de Oliveira, Vanessa Carregaro, Thais S. Farnesi-de-Assunção, Marcelo Henrique Napimoga, Carlos Antonio Trindade da Silva, Alessandra B. Cheraim
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
We evaluate the immunomodulation of Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists 15d-PGJ(2) and rosiglitazone (RGZ) in a model of chronic eosinophilia. 15d-PGJ(2) and RGZ significantly reduce eosinophil migration into the peritone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e0afc2d4a7535ad0254a2e4e591902
https://doi.org/10.1016/j.cellimm.2011.11.010
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9
Exogenous administration of 15d-PGJ2-loaded nanocapsules inhibits bone resorption in a mouse periodontitis model
Autor: Nathalie Ferreira Silva de Melo, Poliana Mendes Duarte, Carlos Antonio Trindade da Silva, Leonardo Fernandes Fraceto, Thais S. Farnesi-de-Assunção, Marcelo Henrique Napimoga, Vanessa Carregaro
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 189(2)
The 15-deoxy-Δ12,14-PG J2 (15d-PGJ2) has demonstrated excellent anti-inflammatory results in different experimental models. It can be used with a polymeric nanostructure system for modified drug release, which can change the therapeutic properties o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4be340ffc6c217165cc49535fdf18bb
https://pubmed.ncbi.nlm.nih.gov/22706081
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10
Akademický článek
Soluble epoxide hydrolase inhibition enhances production of specialized pro‐resolving lipid mediator and promotes macrophage plasticity.
Autor: Abdalla, Henrique B.1,2 (AUTHOR), Alvarez, Carla1 (AUTHOR), Wu, Yu‐Chiao1,3 (AUTHOR), Rojas, Paola1 (AUTHOR), Hammock, Bruce D.4 (AUTHOR), Maddipati, Krishna R.5 (AUTHOR), Trindade‐da‐Silva, Carlos Antonio2 (AUTHOR), Soares, Mariana Q. S.2 (AUTHOR), Clemente‐Napimoga, Juliana T.2 (AUTHOR), Kantarci, Alpdogan1 (AUTHOR), Napimoga, Marcelo H.2 (AUTHOR) marcelo.napimoga@slmandic.edu.br, Van Dyke, Thomas E.1,6 (AUTHOR) tvandyke@forsyth.org
Publikováno v: British Journal of Pharmacology. Jun2023, Vol. 180 Issue 12, p1597-1615. 19p. 7 Graphs.
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