Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carlos A. V. Barreto"'
Autor:
Carlos A. V. Barreto, Salete J. Baptista, António J. Preto, Daniel Silvério, Rita Melo, Irina S. Moreira
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
This paper describes an exciting big data analysis compiled in a freely available database, which can be applied to characterize the coupling of different G-Protein coupled receptors (GPCRs) families with their intracellular partners. Opioid receptor
Externí odkaz:
https://doaj.org/article/c80fb0d774114aedad8ef7a6cbb04402
Autor:
Beatriz Bueschbell, Carlos A. V. Barreto, António J. Preto, Anke C. Schiedel, Irina S. Moreira
Publikováno v:
Molecules, Vol 24, Iss 7, p 1196 (2019)
Background: Selectively targeting dopamine receptors (DRs) has been a persistent challenge in the last years for the development of new treatments to combat the large variety of diseases involving these receptors. Although, several drugs have been su
Externí odkaz:
https://doaj.org/article/bd08a33d1ce24259b622b43b0a4cb6c3
Autor:
Gladys L. Caldeira, R. P. Gouveia, Carlos A. V. Barreto, João Peça, Mohamed Edfawy, Ana Luísa Carvalho, Nuno Beltrão, A. S. Inacio, Joana R. Guedes, R. Macedo, B. Cruz, Susana R. Louros, Irina S. Moreira, Tiago Rondão, M. V. Rodrigues
Publikováno v:
Molecular Psychiatry. 27:2457-2469
Mutations linked to neurodevelopmental disorders, such as intellectual disability (ID), are frequently found in genes that encode for proteins of the excitatory synapse. Transmembrane AMPA receptor regulatory proteins (TARPs) are AMPA receptor auxili
Autor:
Irina S. Moreira, Filipe E. P. Rodrigues, João N. M. Vitorino, Rita Melo, Nícia Rosário-Ferreira, Tomás Silva, Salete J. Baptista, Miguel Machuqueiro, Sara G. F. Ferreira, Bruno L. Victor, Carlos A. V. Barreto
Publikováno v:
ACS Synthetic Biology
SARS-CoV-2 triggered a worldwide pandemic disease, COVID-19, for which an effective treatment has not yet been settled. Among the most promising targets to fight this disease is SARS-CoV-2 main protease (Mpro), which has been extensively studied in t
Autor:
Irina S. Moreira, João D. G. Correia, Pedro Matos-Filipe, Beatriz Bueschbell, Rúben D M Silva, Agostinho Lemos, Jose G. Almeida, António J Preto, Carlos A. V. Barreto, Rita Melo
Publikováno v:
Current Medicinal Chemistry. 27:760-794
Paediatric Acquired ImmunoDeficiency Syndrome (AIDS) is a life-threatening and infectious disease in which the Human Immunodeficiency Virus (HIV) is mainly transmitted through Mother-To- Child Transmission (MTCT) during pregnancy, labour and delivery
Autor:
Agostinho Lemos, Jose G. Almeida, André Melo, Rita Melo, Irina S. Moreira, M. Natália D. S. Cordeiro, António J Preto, Salete J. Baptista, Zeynep Kurkcuoglu, Carlos A. V. Barreto
Publikováno v:
Journal of chemical information and modeling. 60(8)
G-Protein coupled receptors (GPCRs) are involved in a myriad of pathways key for human physiology through the formation of complexes with intracellular partners such as G-proteins and arrestins (Arrs). However, the structural and dynamical determinan
Autor:
Carlos A. V. Barreto, Diana D. Ferreira, Joana Fernandes, Fernando Ribeiro, Sandra Vieira, Ana Sofia Duque, João P F Carvalho, Carolina Gomes, Marisol Gouveia
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(8)
Hypertension is a major and highly prevalent risk factor for various diseases. Among the most frequently prescribed antihypertensive first-line drugs are synthetic angiotensin I-converting enzyme inhibitors (ACEI). However, since their use in hyperte
Autor:
Carlos A V, Barreto, Salete J, Baptista, António José, Preto, Pedro, Matos-Filipe, Joana, Mourão, Rita, Melo, Irina, Moreira
Publikováno v:
Progress in molecular biology and translational science. 169
GPCR oligomerization has emerged as a hot topic in the GPCR field in the last years. Receptors that are part of these oligomers can influence each other's function, although it is not yet entirely understood how these interactions work. The existence
Autor:
Irina S. Moreira, Pedro Matos-Filipe, Rita Melo, Joana Mourão, António J Preto, Salete J. Baptista, Carlos A. V. Barreto
Publikováno v:
ORCID
Microsoft Academic Graph
Progress in Molecular Biology and Translational Science ISBN: 9780128179291
Microsoft Academic Graph
Progress in Molecular Biology and Translational Science ISBN: 9780128179291
GPCR oligomerization has emerged as a hot topic in the GPCR field in the last years. Receptors that are part of these oligomers can influence each other's function, although it is not yet entirely understood how these interactions work. The existence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a628f37336fa4f74818dee68b883f1ef
https://doi.org/10.1016/bs.pmbts.2019.11.007
https://doi.org/10.1016/bs.pmbts.2019.11.007
Autor:
Irina S. Moreira, Anke C. Schiedel, Ozge Sensoy, Carlos A. V. Barreto, Meryem Köse, Giulia Morra, Beatriz Bueschbell
Publikováno v:
Current Topics in Medicinal Chemistry. 18:714-746
Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the direct effect of membrane com