Zobrazeno 1 - 10
of 469
pro vyhledávání: '"Carlos A. Toro"'
Autor:
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed
Externí odkaz:
https://doaj.org/article/07edf235e1324a7b9a58860ef7edcbde
Autor:
Carlos A. Toro, Rita De Gasperi, Abdurrahman Aslan, Nicholas Johnson, Mustafa M. Siddiq, Christine Chow, Wei Zhao, Lauren Harlow, Zachary Graham, Xin-Hua Liu, Junichi Sadoshima, Ravi Iyengar, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 304-316 (2024)
Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces contractil
Externí odkaz:
https://doaj.org/article/c72386503aab4c5bbf2afb087a682fe8
Publikováno v:
Robotics, Vol 13, Iss 8, p 115 (2024)
In this paper, we present a vision-based leader–follower strategy for formation control of multiple quadrotors. The leaders use a decoupled visual control scheme based on invariant features. The followers use a control scheme based only on bearing
Externí odkaz:
https://doaj.org/article/b8b88b8dde7645f68f5325f0c0dd9da2
Autor:
Carlos A. Toro, Jens Hansen, Mustafa M. Siddiq, Kaitlin Johnson, Jiqing Cao, Adriana Pero, Ravi Iyengar, Dongming Cai, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 464-477 (2023)
Apolipoprotein E epsilon 4 (ApoE4) is the second most common variant of ApoE, being present in ?14% of the population. Clinical reports identify ApoE4 as a genetic risk factor for poor outcomes after traumatic spinal cord injury (SCI) and spinal cord
Externí odkaz:
https://doaj.org/article/a46325a807ea45b8958cf91d5ccc95f7
Autor:
Justin C. Burrell, Phuong T. Vu, Owen J. B. Alcott, Carlos A. Toro, Christopher Cardozo, D. Kacy Cullen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Peripheral nerve injury often results in poor functional recovery due to a prolonged period of muscle denervation. In particular, absent axonal contact, denervated muscle can undergo irrevocable atrophy and diminished receptiveness for reinnervation
Externí odkaz:
https://doaj.org/article/9adc9388877743bdbe5f4c2e1f19135e
Autor:
Mustafa M. Siddiq, Nicholas P. Johnson, Yana Zorina, Arjun Singh Yadaw, Carlos A. Toro, Jens Hansen, Vera Rabinovich, Sarah M. Gregorich, Yuguang Xiong, Rosa E. Tolentino, Sari S. Hannila, Ehud Kaplan, Robert D. Blitzer, Marie T. Filbin, Christopher P. Cardozo, Christopher L. Passaglia, Ravi Iyengar
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
There are no known drugs or drug combinations that promote substantial central nervous system axonal regeneration after injury. We used systems pharmacology approaches to model pathways underlying axonal growth and identify a four-drug combination th
Externí odkaz:
https://doaj.org/article/bc2b4a9dfdb640d18ca703e4fcaa209f
Autor:
Mustafa M. Siddiq, Carlos A. Toro, Nicholas P. Johnson, Jens Hansen, Yuguang Xiong, Wilfredo Mellado, Rosa E. Tolentino, Kaitlin Johnson, Gomathi Jayaraman, Zaara Suhail, Lauren Harlow, Jinye Dai, Kristin G. Beaumont, Robert Sebra, Dianna E. Willis, Christopher P. Cardozo, Ravi Iyengar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionNeurons transport mRNA and translational machinery to axons for local translation. After spinal cord injury (SCI), de novo translation is assumed to enable neurorepair. Knowledge of the identity of axonal mRNAs that participate in neurore
Externí odkaz:
https://doaj.org/article/e7907528427c4cc4850262c458caa737
Autor:
Carlos A. Toro, Kaitlin Johnson, Jens Hansen, Mustafa M. Siddiq, Walter Vásquez, Wei Zhao, Zachary A. Graham, Juan C. Sáez, Ravi Iyengar, Christopher P. Cardozo
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Membrane channels such as those formed by connexins (Cx) and P2X7 receptors (P2X7R) are permeable to calcium ions and other small molecules such as adenosine triphosphate (ATP) and glutamate. Release of ATP and glutamate through these channels is a k
Externí odkaz:
https://doaj.org/article/fd2e2acef525478a926bf42909a3ebbd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Female puberty is subject to Polycomb Group (PcG)-dependent transcriptional repression. Kiss1, a puberty-activating gene, is a key target of this silencing mechanism. Using a gain-of-function approach and a systems biology strategy we now sh
Externí odkaz:
https://doaj.org/article/ae4467b975d841c390296873c72d8528
Autor:
Cardona, Carlos Andrés Toro
We prove the impossibility of constructing free boundary minimal M\"obius bands in the Euclidean ball $\mathbb{B}^3$. This answers in the negative a question proposed by I. Fern\'andez, L. Hauswirth and P. Mira.
Externí odkaz:
http://arxiv.org/abs/2404.11101