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pro vyhledávání: '"Carlos A. Gomez-Uribe"'
A longstanding debate surrounds the related hypotheses that low-curvature minima generalize better, and that stochastic gradient descent (SGD) discourages curvature. We offer a more complete and nuanced view in support of both hypotheses. First, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f0b87f86d56dc3290fe52220ea1dae
http://arxiv.org/abs/2108.09507
http://arxiv.org/abs/2108.09507
Autor:
Neil D. Hunt, Carlos A. Gomez-Uribe
Publikováno v:
ACM Transactions on Management Information Systems. 6:1-19
This article discusses the various algorithms that make up the Netflix recommender system, and describes its business purpose. We also describe the role of search and related algorithms, which for us turns into a recommendations problem as well. We e
Publikováno v:
Paul Azunre
The mass fluctuation kinetics (MFK) model is a set of coupled ordinary differential equations approximating the time evolution of means and covariances of species concentrations in chemical reaction networks. It generalises classical mass action kine
Publikováno v:
PMC
available in PMC 2011 June 7.
Negative feedback can serve many different cellular functions, including noise reduction in transcriptional networks and the creation of circadian oscillations. However, only one special type of negative feedback (
Negative feedback can serve many different cellular functions, including noise reduction in transcriptional networks and the creation of circadian oscillations. However, only one special type of negative feedback (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320180cd22185124beb930510126462e
http://hdl.handle.net/1721.1/76690
http://hdl.handle.net/1721.1/76690
Publikováno v:
Science (New York, N.Y.). 319(5862)
The propagation of information through signaling cascades spans a wide range of time scales, including the rapid ligand-receptor interaction and the much slower response of downstream gene expression. To determine which dynamic range dominates a resp
Publikováno v:
The Journal of Chemical Physics. 129:244112
Widely different time scales are common in systems of chemical reactions and can be exploited to obtain reduced models applicable to the time scales of interest. These reduced models enable more efficient computation and simplify analysis. A classic
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 3, Iss 12, p e246 (2007)
PLoS Computational Biology, Vol 3, Iss 12, p e246 (2007)
A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering that can be accomplished by this
Publikováno v:
The Journal of Chemical Physics. 126:024109
The intrinsic stochastic effects in chemical reactions, and particularly in biochemical networks, may result in behaviors significantly different from those predicted by deterministic mass action kinetics (MAK). Analyzing stochastic effects, however,