Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carlos A. Duran-Villalobos"'
Autor:
Linda Wanika, Joseph R. Egan, Nivedhitha Swaminathan, Carlos A. Duran-Villalobos, Juergen Branke, Stephen Goldrick, Mike Chappell
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract Advancements in digital technology have brought modelling to the forefront in many disciplines from healthcare to architecture. Mathematical models, often represented using parametrised sets of ordinary differential equations, can be used to
Externí odkaz:
https://doaj.org/article/da7a9208b906428496f0b411855e299e
Publikováno v:
Journal of Process Control. 108:148-156
Autor:
Carlos A. Duran-Villalobos, Beatrice Melinek, Barry Lennox, Daniel G. Bracewell, Trevor Hallam, Olotu Ogonah
Publikováno v:
Duran Villalobos, C A, Ogonah, O, Melinek, B, Bracewell, D, Hallam, T & Lennox, B 2021, ' Multivariate statistical data analysis of cell-free protein synthesis toward monitoring and control ', AIChE Journal, pp. 1-12 . https://doi.org/10.1002/aic.17257
The optimization and control of cell free protein synthesis (CFPS) presents an ongoing challenge due to the complex synergies and nonlinearities that cannot be fully explained in first principle models. This article explores the use of multivariate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a8813e216d3edc110e1450d48572a3
https://doi.org/10.1002/aic.17257
https://doi.org/10.1002/aic.17257
Autor:
Barry Lennox, Carlos A. Duran-Villalobos, Suzanne S. Farid, Stephen Goldrick, David Lovett, Karolis Jankauskas
Publikováno v:
Goldrick, S, Duran-villalobos, C A, Jankauskas, K, Lovett, D, Farid, S S & Lennox, B 2019, ' Modern day monitoring and control challenges outlined on an industrial-scale benchmark fermentation process ', COMPUTERS & CHEMICAL ENGINEERING . https://doi.org/10.1016/j.compchemeng.2019.05.037
This paper outlines real-world control challenges faced by modern-day biopharmaceutical facilities through the extension of a previously developed industrial-scale penicillin fermentation simulation (IndPenSim). The extensions include the addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04a9399444febd1f389aea58d70529c
https://doi.org/10.1016/j.compchemeng.2019.05.037
https://doi.org/10.1016/j.compchemeng.2019.05.037
Publikováno v:
Duran-villalobos, C A, Goldrick, S & Lennox, B 2019, ' Multivariate statistical process control of an industrial-scale fed-batch simulator. ', COMPUTERS & CHEMICAL ENGINEERING, pp. 106620 . https://doi.org/10.1016/j.compchemeng.2019.106620, https://doi.org/10.1016/j.compchemeng.2019.106620
This article presents an improved batch-to-batch optimisation technique that is shown to be able to bring the yield closer to its set-point from one batch to the next. In addition, an innovative Model Predictive Control technique is proposed that ove
Publikováno v:
IFAC Proceedings Volumes. 46:511-516
In this paper a novel method for batch-to-batch modelling and optimization, Iterative Learning Partial Least Squares Optimization (IL-PLSO) is proposed. This method uses a recursive technique to update a multi-way PLS model so that it is able to trac