Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Carlos A V Rodrigues"'
Autor:
Sofia P. Agostinho, Mariana A. Branco, Diogo E. S. Nogueira, Maria Margarida Diogo, Joaquim M. S. Cabral, Ana L. N. Fred, Carlos A. V. Rodrigues
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The main objective of the present work was to highlight differences and similarities in gene expression patterns between different pluripotent stem cell cardiac differentiation protocols, using a workflow based on unsupervised machine learni
Externí odkaz:
https://doaj.org/article/640f5d5a2b2943afa7777f2120f816d5
Autor:
Silvia Gonella, Margarida F. Domingues, Filipe Miguel, Carla S. Moura, Carlos A. V. Rodrigues, Frederico Castelo Ferreira, João C. Silva
Publikováno v:
Gels, Vol 10, Iss 7, p 422 (2024)
Functional articular cartilage regeneration remains an unmet medical challenge, increasing the interest for innovative biomaterial-based tissue engineering (TE) strategies. Hydrogels, 3D macromolecular networks with hydrophilic groups, present articu
Externí odkaz:
https://doaj.org/article/5505fedfabce45f69838c00b7f2ccd78
Autor:
William O. S. Salvador, Inês A. B. Ribeiro, Diogo E. S. Nogueira, Frederico C. Ferreira, Joaquim M. S. Cabral, Carlos A. V. Rodrigues
Publikováno v:
Bioengineering, Vol 9, Iss 12, p 791 (2022)
Over recent years, the field of cell and gene therapy has witnessed rapid growth due to the demonstrated benefits of using living cells as therapeutic agents in a broad range of clinical studies and trials. Bioprocess economic models (BEMs) are funda
Externí odkaz:
https://doaj.org/article/f5cafa8a4cae44f48137f24f2fddcc75
Autor:
Diogo E. S. Nogueira, Carlos A. V. Rodrigues, Marta S. Carvalho, Cláudia C. Miranda, Yas Hashimura, Sunghoon Jung, Brian Lee, Joaquim M. S. Cabral
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-14 (2019)
Abstract Background Since their inception, human induced pluripotent stem cells (hiPSCs) have held much promise for pharmacological applications and cell-based therapies. However, their potential can only be realised if large numbers of cells can be
Externí odkaz:
https://doaj.org/article/7d2e37bd0ecc420b9317d188c5b52f88
Autor:
Pedro M. Neto, Diogo E. S. Nogueira, Yas Hashimura, Sunghoon Jung, Bruno Pedras, Mário N. Berberan-Santos, Tiago Palmeira, Brian Lee, Joaquim M. S. Cabral, Vitor Geraldes, Carlos A. V. Rodrigues
Publikováno v:
Bioengineering, Vol 9, Iss 8, p 386 (2022)
In this work, the oxygen transport and hydrodynamic flow of the PBS Vertical-Wheel MINI™ 0.1 bioreactor were characterized using experimental data and computational fluid dynamics simulations. Data acquired from spectroscopy-based oxygenation measu
Externí odkaz:
https://doaj.org/article/a55fffce7f5c4938bc19f5fa0d6902ed
Autor:
Laura Sordini, Fábio F. F. Garrudo, Carlos A. V. Rodrigues, Robert J. Linhardt, Joaquim M. S. Cabral, Frederico Castelo Ferreira, Jorge Morgado
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The ability to culture and differentiate neural stem cells (NSCs) to generate functional neural populations is attracting increasing attention due to its potential to enable cell-therapies to treat neurodegenerative diseases. Recent studies have show
Externí odkaz:
https://doaj.org/article/ab67b07435224a8999cf61d33e053fe8
Autor:
Miguel de Almeida Fuzeta, Nuno Bernardes, Filipa D. Oliveira, Ana Catarina Costa, Ana Fernandes-Platzgummer, José Paulo Farinha, Carlos A. V. Rodrigues, Sunghoon Jung, Rong-Jeng Tseng, William Milligan, Brian Lee, Miguel A. R. B. Castanho, Diana Gaspar, Joaquim M. S. Cabral, Cláudia Lobato da Silva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based therapies due to their multilineage differentiation potential and intrinsic immunomodulatory and trophic activities. Over the past years, increasing evidence has
Externí odkaz:
https://doaj.org/article/b500df7c63514a22843cbaa239e4e991
Autor:
Miriam C. Amores de Sousa, Carlos A. V. Rodrigues, Inês A. F. Ferreira, Maria Margarida Diogo, Robert J. Linhardt, Joaquim M. S. Cabral, Frederico Castelo Ferreira
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Neural stem cells (NSCs) have the potential to generate the cells of the nervous system and, when cultured on nanofiber scaffolds, constitute a promising approach for neural tissue engineering. In this work, the impact of combining nanofiber alignmen
Externí odkaz:
https://doaj.org/article/397aaf712650441d9944240eaa7e7022
Autor:
Teresa P. Silva, Evguenia P. Bekman, Tiago G. Fernandes, Sandra H. Vaz, Carlos A. V. Rodrigues, Maria Margarida Diogo, Joaquim M. S. Cabral, Maria Carmo-Fonseca
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The cerebellum plays a critical role in all vertebrates, and many neurological disorders are associated with cerebellum dysfunction. A major limitation in cerebellar research has been the lack of adequate disease models. As an alternative to animal m
Externí odkaz:
https://doaj.org/article/cbdf6bcb493145a29a8901a8931a17d6
Autor:
Brian Lee, Sunghoon Jung, Yas Hashimura, Maximilian Lee, Breanna S. Borys, Tiffany Dang, Michael S. Kallos, Carlos A. V. Rodrigues, Teresa P. Silva, Joaquim M. S. Cabral
Publikováno v:
Bioengineering, Vol 9, Iss 3, p 92 (2022)
Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges related to
Externí odkaz:
https://doaj.org/article/47483c05b1ef4895932fffd080a3c19e