Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Carlos A García-Pérez"'
Autor:
Yamelie A Martínez, Xianwu Guo, Diana P Portales-Pérez, Gildardo Rivera, Julio E Castañeda-Delgado, Carlos A García-Pérez, José A Enciso-Moreno, Edgar E Lara-Ramírez
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246901 (2021)
The MERS-CoV, SARS-CoV, and SARS-CoV-2 are highly pathogenic viruses that can cause severe pneumonic diseases in humans. Unfortunately, there is a non-available effective treatment to combat these viruses. Domain-motif interactions (DMIs) are an esse
Externí odkaz:
https://doaj.org/article/f61c05a9d8614edc903c25fdac412f68
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71526 (2013)
Protein interactions between a pathogen and its host are fundamental in the establishment of the pathogen and underline the infection mechanism. In the present work, we developed a single predictive model for building a host-viral interactome based o
Externí odkaz:
https://doaj.org/article/75a92e5da2bf4e51a52cb39966ec1f8b
Autor:
Fabiola Cortés-Mendoza, Diana Casique-Aguirre, Carlos A. García-Pérez, Sonia Mayra Pérez-Tapia, Aliesha González-Arenas, Inés Velázquez-Quesada, Marisol de la Fuente-Granada, Charmina Aguirre-Alvarado, Angel J Ruiz-Moreno, Aldo Segura-Cabrera, Marco A. Velasco-Velázquez
Publikováno v:
Drug Design, Development and Therapy. 14:1799-1811
Introduction Cancer stem cells (CSCs) drive the initiation, maintenance, and therapy response of breast tumors. CD49f is expressed in breast CSCs and functions in the maintenance of stemness. Thus, blockade of CD49f is a potential therapeutic approac
Autor:
Eduardo, Amaya-Fragoso, Mayra Alondra, Dantés-Duran, Erika Karina, Pérez-Torres, Carlos Marcel, García-Pérez
Publikováno v:
Revista medica del Instituto Mexicano del Seguro Social. 59(3)
Osteoclast-like giant cell bladder carcinomas are an extremely unusual and aggressive histological subtype of urothelial carcinomas. Only 30 cases are reported in the international literature.A 79-year-old male patient attended our Urology department
Autor:
Gildardo Rivera, Diana P. Portales-Pérez, Xianwu Guo, Julio Enrique Castañeda-Delgado, José Antonio Enciso-Moreno, Yamelie A. Martínez, Edgar E. Lara-Ramírez, Carlos A. García-Pérez
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246901 (2021)
PLoS ONE
PLoS ONE 16:e0246901 (2021)
PLoS ONE
PLoS ONE 16:e0246901 (2021)
The MERS-CoV, SARS-CoV, and SARS-CoV-2 are highly pathogenic viruses that can cause severe pneumonic diseases in humans. Unfortunately, there is a non-available effective treatment to combat these viruses. Domain-motif interactions (DMIs) are an esse
Autor:
José-Lázaro Martínez-Rodríguez, Génesis Varela-Salinas, Hugo E. Camacho-Cruz, Josue Rodriguez-Rodriguez, Carlos A. García-Pérez, Alfredo Juarez Saldivar
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783030862701
HAIS
HAIS
Toxicity in drug design is a very important step prior to human or animal evaluation phases. Establishing drug toxicity involves the modification or redesign of the drug into an analog to suppress or reduce the toxicity. In this work, two different d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::555ed9ce4c373a59698b9ac181759d2f
https://doi.org/10.1007/978-3-030-86271-8_13
https://doi.org/10.1007/978-3-030-86271-8_13
Autor:
V. Joachim Haupt, Carlos A. García-Pérez, Citlali Vázquez, Juan Carlos Villalobos-Rocha, Emma Saavedra, Sebastian Salentin, Alfredo Juárez-Saldivar, Nuria E. Campillo, Verónica Herrera-Mayorga, Francisco Reyes-Espinosa, Gildardo Rivera, Michael Schroeder
Publikováno v:
Int. J. Mol. Sci. 21:4270 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4270, p 4270 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4270, p 4270 (2020)
Chagas disease, caused by Trypanosoma cruzi (T. cruzi), affects nearly eight million people worldwide. There are currently only limited treatment options, which cause several side effects and have drug resistance. Thus, there is a great need for a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aec3565ac9f21c45640b40f2f1c34b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59506
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59506
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 39:831.e11-831.e18
Background Prostate cancer screening has reduced its mortality in 21%. However, this has also led to an increased number of biopsies in order to establish the diagnosis, many of them unnecessary. Current screening guidelines prioritize use of prostat
Autor:
Isidro Palos, Gildardo Rivera, Verónica Herrera-Mayorga, Francisco Reyes-Espinosa, Alfredo Juárez-Saldivar, Carlos A. García-Pérez
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 6
Int. J. Mol. Sci. 20:1320 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1320 (2019)
Volume 20
Issue 6
Int. J. Mol. Sci. 20:1320 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1320 (2019)
The present study gives an overview of the binding energetics of the homologous heterodimers of cruzipain&minus
chagasin based on the binding energy (&Delta
Gb) prediction obtained with FoldX. This analysis involves a total of 70 homologous
chagasin based on the binding energy (&Delta
Gb) prediction obtained with FoldX. This analysis involves a total of 70 homologous
Autor:
Inés Velázquez-Quesada, Aldo Segura-Cabrera, Sandra L. Guerrero-Rodríguez, Charmina Aguirre-Alvarado, Carlos A. García-Pérez, Sonia Mayra Pérez-Tapia, Andrea Rodríguez-Moreno, Angel J Ruiz-Moreno, Miguel A. Hernandez-Esquivel, Marco A. Velasco-Velázquez
Publikováno v:
Oncotarget
CD44 is a receptor for hyaluronan (HA) that promotes epithelial-to-mesenchymal transition (EMT), induces cancer stem cell (CSC) expansion, and favors metastasis. Thus, CD44 is a target for the development of antineoplastic agents. In order to repurpo