Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Carlos A Fraga"'
Autor:
Solja Säde, Grégoire Delaporte, Carlos G. Fraga, Hanna Hakulinen, Karin Höjer Holmgren, Marie Spiandore, Crister Åstot, Anuradha Akmeemana, Mirjam de Bruin-Hoegée, Justin Doward, Karen Jacques, Saiful Anuar Kesah, Samantha See, Stuart Thomson, Jens Flinck, Leena Kalliovirta, Paula Vanninen
Publikováno v:
Talanta Open, Vol 8, Iss , Pp 100249- (2023)
A new quality control (QC) test sample for gas chromatography–mass spectrometry (GC–MS) was created and analysed to test the comparability and repeatability of chemical forensics results within the Organisation for the Prohibition of Chemical Wea
Externí odkaz:
https://doaj.org/article/9da84f7f1c764b45bd7c56c40e667605
Autor:
Yara Refaat Hassan, Filipe Brogueira Rodrigues, Paul Zeun, Lauren M. Byrne, Carlos Estevez-Fraga, Rosanna Tortelli, Rachael I. Scahill, Edward J. Wild, Sarah J. Tabrizi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Lumbar puncture (LP) has become increasingly common for people with Huntington’s disease (HD) both to administer intrathecal investigational medicinal products and to collect cerebrospinal fluid to develop biological markers to track disea
Externí odkaz:
https://doaj.org/article/ad4a5e730417443781456cf2e0327ad6
Autor:
Carlos Eduardo Fraga
Publikováno v:
Revista Trágica, Vol 16, Iss 1 (2023)
Este artigo utiliza a filosofia de Spinoza para pensar o problema da dependência de drogas psicoativas. Partindo-se do conceito de desejo como essência do ser humano, busca-se uma definição para a drogadição. Somente a explicando como uma afec
Externí odkaz:
https://doaj.org/article/282079a7afd14bb485224d073237cddf
Progressive alterations in white matter microstructure across the timecourse of Huntington's disease
Autor:
Carlos Estevez‐Fraga, Michael S. Elmalem, Marina Papoutsi, Alexandra Durr, Elin M. Rees, Nicola Z. Hobbs, Raymund A. C. Roos, Bernhard Landwehrmeyer, Blair R. Leavitt, Douglas R. Langbehn, Rachael I. Scahill, Geraint Rees, Sarah J. Tabrizi, Sarah Gregory
Publikováno v:
Brain and Behavior, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Background Whole‐brain longitudinal diffusion studies are crucial to examine changes in structural connectivity in neurodegeneration. Here, we investigated the longitudinal alterations in white matter (WM) microstructure across the timecou
Externí odkaz:
https://doaj.org/article/14760f7b295f464cbc8b231b3d170168
Autor:
María del Carmen Franco Suárez, Jesús Menéndez Jiménez, Maira Mena Correa, Anays Montequín Jiménez, Norkis Plasencia Padrón, Mercedes Mena Martínez, Ebel Quesada Gutiérrez, Adialys Guevara González, Juan Carlos Alfonso Fraga, Diego Enrique González Galbán, Alejandro Rodríguez Orama, Zaily Davis Serrano, Enrique Frómeta Sánchez, Daysi García Agustín, Tatiana Rodríguez Trejo
Publikováno v:
Anales de la Academia de Ciencias de Cuba, Vol 12, Iss 3 (2022)
Introducción. Cuba tiene un 20,8 % de su población con 60 años o más, cifra relativamente homogénea en todos sus territorios y que ha mostrado una tendencia creciente a lo largo del tiempo y en la perspectiva. Esta investigación constituye la
Externí odkaz:
https://doaj.org/article/8d64973daa40454897eb1ca82319e352
Autor:
Carlos A. Fraga Castillo
Publikováno v:
Perfiles Latinoamericanos, Vol 29, Iss 58 (2021)
El objetivo de esta investigación es examinar teórica y empíricamente las deseconomías de escala y las tecnologías intermedias en el sector del agua en la Ciudad de México. La concentración demográfica de esta ciudad puede disminuir los costo
Externí odkaz:
https://doaj.org/article/31d4d20ab27c4574aef106a25fe88209
Autor:
Carlos A.M. Fraga, Giulianna P. de Alcântara, Juliana M.C. Barbosa, Kelly Salomão, Solange L. de Castro, James L. Wardell, John N. Low, Solange M.S.V. Wardell, Samir A. Carvalho, Edson F. da Silva
Publikováno v:
Letters in Drug Design & Discovery. 20:488-497
Background: The drugs available for the treatment of Chagas disease are ineffective in its chronic phase and produce many adverse effects, making the search for new drugs an urgent medical need. Objective: This study aimed to design, synthesize, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508b257477d31508daa851213480b21f
https://doi.org/10.2174/1570180819666220512121029
https://doi.org/10.2174/1570180819666220512121029
Autor:
Eileanoir B. Johnson, Christopher S. Parker, Rachael I. Scahill, Sarah Gregory, Marina Papoutsi, Paul Zeun, Katherine Osborne-Crowley, Jessica Lowe, Akshay Nair, Carlos Estevez-Fraga, Kate Fayer, Geraint Rees, Hui Zhang, Sarah J. Tabrizi
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103266- (2021)
Background: Pathological processes in Huntington's disease (HD) begin many years prior to symptom onset. Recently we demonstrated that in a premanifest cohort approximately 24 years from predicted disease onset, despite intact function, there was evi
Externí odkaz:
https://doaj.org/article/a5b119aef0874e58add8c97f8d4a0310
Publikováno v:
Journal of Huntington's Disease. 11:351-367
In this edition of the Huntington’s Disease Clinical Trials Corner, we expand on the PIVOT HD (PTC518), and SIGNAL (pepinemab) trials, and list all currently registered and ongoing clinical trials in Huntington’s disease. We also introduce a ‘b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323ef2031bd47e005dc000ae5a26c213
https://doi.org/10.3233/jhd-229006
https://doi.org/10.3233/jhd-229006
Autor:
Rosana H.C.N. Freitas, Juliana M.C. Barbosa, Patrícia Bernardino, Vitor Sueth-Santiago, Solange M.S.V. Wardell, James L. Wardell, Débora Decoté-Ricardo, Tatiana G. Melo, Edson F. da Silva, Kelly Salomão, Carlos A.M. Fraga
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss , Pp 110162- (2020)
Herein, we present the design, synthesis and trypanocidal evaluation of sixteen new 1,3,4-thiadiazole derivatives from N-aminobenzyl or N-arylhydrazone series. All derivatives were assayed against the trypomastigote form of Trypanosoma cruzi, showing
Externí odkaz:
https://doaj.org/article/2913247f852a4bbe8cac3322fa6ea291