Výsledky vyhledávání - "Carlos, Escande"

Akademický článek

Impact of Bariatric Surgery on metabolic health in a Uruguayan cohort and the emerging predictive role of FSTL1

Autor: Leonardo Santos, Mariana Patrone, Victoria Prieto-Echagüe, Silvana Lapi, Mauro Perdomo, Andrea Vaucher, Gustavo Rodriguez, Pablo Valsangiacomo, Hugo Naya, Carlos Escande, Jose L. Badano, Lucia Spangenberg, Gustavo Bruno

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract Obesity poses significant challenges, necessitating comprehensive strategies for effective intervention. Bariatric Surgery (BS) has emerged as a crucial therapeutic approach, demonstrating success in weight loss and comorbidity improvement.

Externí odkaz: https://doaj.org/article/2eebf21f4ad24772b7858664daa6a171

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Akademický článek

CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline

Publikováno v: Cell Reports, Vol 42, Iss 10, Pp 113269- (2023)

Summary: Emerging evidence suggests that immune receptors may participate in many aging-related processes such as energy metabolism, inflammation, and cognitive decline. CD300f, a TREM2-like lipid-sensing immune receptor, is an exceptional receptor a

Externí odkaz: https://doaj.org/article/d519438bc10c484aad49f226011c5dfa

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Akademický článek

Flow Cytometry Analysis of SIRT6 Expression in Peritoneal Macrophages

Autor: Valentina Pérez-Torrado, Jorge Rodríguez-Duarte, Carlos Escande, Mariana Bresque

Publikováno v: Bio-Protocol, Vol 12, Iss 19 (2022)

The sirtuin 6 has emerged as a regulator of acute and chronic immune responses. Recent findings show that SIRT6 is necessary for mounting an active inflammatory response in macrophages. In vitro studies revealed that SIRT6 is stabilized in the cytopl

Externí odkaz: https://doaj.org/article/add32a3d58a4426eb79b4055e5aa327f

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Akademický článek

Peripheral and respiratory muscle impairment during murine acute lung injury

Autor: Martín Angulo, Agustina Vacca, Romina Rodríguez, María Noel Marin, Ana Laura Suárez, Gissel Jorge, Oscar Nosiglia, Victoria Cambón, Anaclara Ríos, Matías Iglesias, Mariana Seija, Carlos Escande, Javier Hurtado, Arturo Briva

Publikováno v: Physiological Reports, Vol 10, Iss 17, Pp n/a-n/a (2022)

Abstract Acute respiratory distress syndrome is associated with skeletal muscle compromise, which decreases survival and impairs functional capacity. A comparative analysis of peripheral and respiratory muscles' atrophy and dysfunction in acute lung

Externí odkaz: https://doaj.org/article/5a1ee7ad582543208d5f254d82f6f661

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Akademický článek

Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with mild social behavioral phenotypes.

Autor: Matías Fabregat, Sofía Niño-Rivero, Sabrina Pose, Magdalena Cárdenas-Rodríguez, Mariana Bresque, Karina Hernández, Victoria Prieto-Echagüe, Geraldine Schlapp, Martina Crispo, Patricia Lagos, Natalia Lago, Carlos Escande, Florencia Irigoín, Jose L Badano

Publikováno v: PLoS Genetics, Vol 18, Iss 6, p e1009896 (2022)

CCDC28B (coiled-coil domain-containing protein 28B) was identified as a modifier in the ciliopathy Bardet-Biedl syndrome (BBS). Our previous work in cells and zebrafish showed that CCDC28B plays a role regulating cilia length in a mechanism that is n

Externí odkaz: https://doaj.org/article/1600228874ff479e88d5faccebff402c

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Akademický článek

A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity

Autor: Rosina Dapueto, Jorge Rodriguez-Duarte, Germán Galliussi, Andrés Kamaid, Mariana Bresque, Carlos Batthyány, Gloria V. López, Carlos Escande

Publikováno v: Redox Biology, Vol 39, Iss , Pp 101833- (2021)

Chronic metabolic diseases, like obesity, type II diabetes and atherosclerosis often involve a low-grade and sterile systemic inflammatory state, in which activation of the pro-inflammatory transcription factor NF-kB and the NLRP3 inflammasome play a

Externí odkaz: https://doaj.org/article/fd342c50fe4445279342c16afc73566b

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