Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Carlo V, Catapano"'
Autor:
Alessia Cacciatore, Dheeraj Shinde, Carola Musumeci, Giada Sandrini, Luca Guarrera, Domenico Albino, Gianluca Civenni, Elisa Storelli, Simone Mosole, Elisa Federici, Alessio Fusina, Marta Iozzo, Andrea Rinaldi, Matteo Pecoraro, Roger Geiger, Marco Bolis, Carlo V. Catapano, Giuseppina M. Carbone
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Castration-resistant prostate cancer (CRPC) is a frequently occurring disease with adverse clinical outcomes and limited therapeutic options. Here, we identify methionine adenosyltransferase 2a (MAT2A) as a critical driver of the androgen-in
Externí odkaz:
https://doaj.org/article/724f72ec506f4c06aa1670dd1c8ab69a
Autor:
Evangelia Lekka, Aleksandra Kokanovic, Simone Mosole, Gianluca Civenni, Sandro Schmidli, Artur Laski, Alice Ghidini, Pavithra Iyer, Christian Berk, Alok Behera, Carlo V. Catapano, Jonathan Hall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The Lin28/let-7 axis regulates metabolic pathways in normal and pathological contexts. Here the authors show that pharmacological inhibition of Lin28 protects against lipid accumulation in multiple preclinical models of nonalcoholic fatty liver disea
Externí odkaz:
https://doaj.org/article/4eb77299f3fe4991b4cc526dc0ff726c
Autor:
Stefano Cacciatore, Martha Wium, Cristina Licari, Aderonke Ajayi-Smith, Lorenzo Masieri, Chanelle Anderson, Azola Samkele Salukazana, Lisa Kaestner, Marco Carini, Giuseppina M. Carbone, Carlo V. Catapano, Massimo Loda, Towia A. Libermann, Luiz F. Zerbini
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background Men with African ancestry are more likely to develop aggressive prostate cancer (PCa) and to die from this disease. The study of PCa in the South African population represents an opportunity for biomedical research due to the high
Externí odkaz:
https://doaj.org/article/455b5f98b8da4e75a5af428d053f1584
Autor:
Marita Zoma, Laura Curti, Dheeraj Shinde, Domenico Albino, Abhishek Mitra, Jacopo Sgrignani, Sarah N. Mapelli, Giada Sandrini, Gianluca Civenni, Jessica Merulla, Giovanna Chiorino, Paolo Kunderfranco, Alessia Cacciatore, Aleksandra Kokanovic, Andrea Rinaldi, Andrea Cavalli, Carlo V. Catapano, Giuseppina M. Carbone
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Although the TMPRSS2-ERG gene fusion is the most common alteration in human prostate cancer, its involvement in disease progression remains unclear. Here, the authors demonstrate that ERG is methylated by Enhancer of zest homolog 2 leading to enhance
Externí odkaz:
https://doaj.org/article/e634d5688e6b4dc7aff08bbd1aa3f1c9
Autor:
Domenico Albino, Martina Falcione, Valeria Uboldi, Dada Oluwaseyi Temilola, Giada Sandrini, Jessica Merulla, Gianluca Civenni, Aleksandra Kokanovic, Alessandra Stürchler, Dheeraj Shinde, Mariangela Garofalo, Ricardo Pereira Mestre, Vera Constâncio, Martha Wium, Jacopo Burrello, Nicolò Baranzini, Annalisa Grimaldi, Jean-Philippe Theurillat, Daniela Bossi, Lucio Barile, Rui M. Henrique, Carmen Jeronimo, Luiz Fernando Zerbini, Carlo V. Catapano, Giuseppina M. Carbone
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Following on reports that miR-424 expression promotes oncogenesis, Domenico Albino et al. find that extracellular vesicles (EVs) in the plasma of prostate cancer patients secrete miR-424. Using cell-based and animal models, they demonstrate that EV-m
Externí odkaz:
https://doaj.org/article/28200d6da1754aecbc8751a32e04f961
Autor:
Giuseppina Pisignano, Sara Napoli, Marco Magistri, Sarah N. Mapelli, Chiara Pastori, Stefano Di Marco, Gianluca Civenni, Domenico Albino, Claudia Enriquez, Sara Allegrini, Abhishek Mitra, Gioacchino D’Ambrosio, Maurizia Mello-Grand, Giovanna Chiorino, Ramon Garcia-Escudero, Gabriele Varani, Giuseppina M. Carbone, Carlo V. Catapano
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Promoter-proximal transcripts have been proposed to act ascis-acting elements regulating transcription. Here, the authors provide evidence that a promoter-proximal RNA, in combination with other epigenetic regulators, controls transcription of E-cadh
Externí odkaz:
https://doaj.org/article/30abb6e59ccc403ba1c9e976c95d4eef
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 5 (2019)
The emergence of therapy-resistant cancer stem cells (CSCs) limit the efficacy of prostate cancer treatment. Using genetic knockdown and chemical inhibitors, we demonstrate the critical role of Bromodomain Containing 4 (BRD4) in promoting mitochondri
Externí odkaz:
https://doaj.org/article/f761285377c6439c840deaba4c2a4c43
Autor:
Gianluca Civenni, Domenico Albino, Dheeraj Shinde, Ramiro Vázquez, Jessica Merulla, Aleksandra Kokanovic, Sarah N. Mapelli, Giuseppina M. Carbone, Carlo V. Catapano
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Prostate cancer is the most common malignancy in men and the second cause of cancer-related deaths in western countries. Despite the progress in the treatment of localized prostate cancer, there is still lack of effective therapies for the advanced f
Externí odkaz:
https://doaj.org/article/7def8a046cad40a3aab47f3e7b7232d6
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4885daffb61a5308ac13699a54e146b1
https://doi.org/10.1002/cpz1.742
https://doi.org/10.1002/cpz1.742
Autor:
Carlo V. Catapano, Giuseppina M. Carbone, Francisco Morís, Luz Elena Nuñez, Domenico Albino, Cristina García Inclán, Cecilia Dallavalle, Paula Costales, Nicole Longoni, Gianluca Civenni
Supplementary figure 1. Immunofluorescence microscopy detection of p65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7c4badf724310d160949a79c9d1696
https://doi.org/10.1158/1535-7163.22508773
https://doi.org/10.1158/1535-7163.22508773
