Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Carlo Unverzagt"'
Autor:
Tom L. Gallinger, Samuel Y. Aboagye, Wiebke Obermann, Michael Weiss, Arnold Grünweller, Carlo Unverzagt, David L. Williams, Martin Schlitzer, Simone Haeberlein
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 119 (2022)
Schistosomiasis is a neglected tropical disease caused by blood flukes of the genus Schistosoma. In silico screenings of compounds for the identification of novel anti-parasitic drug candidates have received considerable attention in recent years, in
Externí odkaz:
https://doaj.org/article/29a5cf11c1a04b6bbf5a32fd2c925484
Autor:
Steffen Riethmueller, Prasath Somasundaram, Johanna C Ehlers, Chien-Wen Hung, Charlotte M Flynn, Juliane Lokau, Maria Agthe, Stefan Düsterhöft, Yijue Zhu, Joachim Grötzinger, Inken Lorenzen, Tomas Koudelka, Kosuke Yamamoto, Ute Pickhinke, Rielana Wichert, Christoph Becker-Pauly, Marisa Rädisch, Alexander Albrecht, Markus Hessefort, Dominik Stahnke, Carlo Unverzagt, Stefan Rose-John, Andreas Tholey, Christoph Garbers
Publikováno v:
PLoS Biology, Vol 15, Iss 1, p e2000080 (2017)
Signaling of the cytokine interleukin-6 (IL-6) via its soluble IL-6 receptor (sIL-6R) is responsible for the proinflammatory properties of IL-6 and constitutes an attractive therapeutic target, but how the sIL-6R is generated in vivo remains largely
Externí odkaz:
https://doaj.org/article/0de46d7cf5e847c6bf5e71b31996514a
Autor:
Aymeric Audfray, Mona Beldjoudi, Adrien Breiman, Amandine Hurbin, Irene Boos, Carlo Unverzagt, Mourad Bouras, Sylvie Lantuejoul, Jean-Luc Coll, Annabelle Varrot, Jacques Le Pendu, Benoit Busser, Anne Imberty
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128190 (2015)
Cell surface glycoconjugates present alterations of their structures in chronic diseases and distinct oligosaccharide epitopes have been associated with cancer. Among them, truncated glycans present terminal non-reducing β-N-acetylglucosamine (GlcNA
Externí odkaz:
https://doaj.org/article/270d0d5ed44046fca557c15231bb4672
Autor:
Carlo, Unverzagt, Yasuhiro, Kajihara
Publikováno v:
In Current Opinion in Chemical Biology October 2018 46:130-137
Autor:
Chengzhang Xu, Alexander Battig, Bernhard Schartel, Renée Siegel, Jürgen Senker, Inge von der Forst, Carlo Unverzagt, Seema Agarwal, Andreas Möglich, Andreas Greiner
Publikováno v:
Biomacromolecules. 23:4841-4850
The enzymatic degradation of aliphatic polyesters offers unique opportunities for various use cases in materials science. Although evidently desirable, the implementation of enzymes in technical applications of polyesters is generally challenging due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ca912e4050d6d587878363d7088962
https://doi.org/10.1021/acs.biomac.2c01008
https://doi.org/10.1021/acs.biomac.2c01008
Publikováno v:
Arkivoc. 2021:206-229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b88fb61322826431a503675f9bd0011
https://doi.org/10.24820/ark.5550190.p011.380
https://doi.org/10.24820/ark.5550190.p011.380
Autor:
Israel Alshanski, Ariel Shitrit, Yonatan Sukhran, Carlo Unverzagt, Mattan Hurevich, Shlomo Yitzchaik
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 38(2)
Sensing enzymatic sialylation provides new tools for the evaluation of pathological events and pathogen invasion. Enzymatic sialylation is usually monitored via fluorescence or metabolic labeling, which requires relatively large amounts of the glycan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ef1b169d777a612d4137c8a41053b2
https://pubmed.ncbi.nlm.nih.gov/34989586
https://pubmed.ncbi.nlm.nih.gov/34989586
Autor:
Hendrik Hessefort, Elisabeth Rozanski, Carlo Unverzagt, Sascha Weidler, Karen Gottwald, Lukas Perkams, Tanja Kirsch, Simone Seeleithner, Markus Hessefort, Klaus Ole Bundgaard, Angelina Gross, David Rau, Christopher Günther Franz Graf
Publikováno v:
Angewandte Chemie (International ed. in English). 60(49)
Recombinant human erythropoietin (EPO) is the main therapeutic glycoprotein for the treatment of anemia in cancer and kidney patients. The in-vivo activity of EPO is carbohydrate-dependent with the number of sialic acid residues regulating its circul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a93e7e119a29a5827f5e541c370b9d5
https://pubmed.ncbi.nlm.nih.gov/34523784
https://pubmed.ncbi.nlm.nih.gov/34523784
Autor:
Kevin Lam, Christopher Günther Franz Graf, Marie Lott, Stefan Rose-John, Manuel Mönnich, Carlo Unverzagt, Irene Boos, Michael Weyand, Christoph Garbers, Carolin Lechner, Stefan Becker, Jan-Patrick Fischer, Juliane Lokau, Clemens Steegborn, Christian Bretscher, Gerhard Schultheiss, Sascha Weidler, Lukas Perkams, Kerstin Hallstein, Marina Schmälzlein, Andreas Reif
Publikováno v:
Angewandte Chemie (International Ed. in English)
A library of glycoforms of human interleukin 6 (IL‐6) comprising complex and mannosidic N‐glycans was generated by semisynthesis. The three segments were connected by sequential native chemical ligation followed by two‐step refolding. The centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4702254cf7e3275a35dabd64a5b07735
Autor:
Marie Lott, Angelina Gross, David Rau, Hendrik Hessefort, Simone Seeleithner, Carlo Unverzagt, Laura Kern, Markus Hessefort
Publikováno v:
Journal of Peptide Science. 27
A convergent synthesis for erythropoietin (EPO) 1-28 N-glycopeptide hydrazides was developed. In this approach, EPO 1-28 peptides were synthesized on the solid phase and converted to C-terminal hydrazides after cleavage from the resin. After selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c92774fcd18d90904356c215555a060
https://doi.org/10.1002/psc.3283
https://doi.org/10.1002/psc.3283