Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carlo Salas Salinas"'
Autor:
Frank Chinga, Serge Y. Fuchs, Zoya Ignatova, Jiangbin Ye, Crystal S. Conn, Weixuan Fu, Constantinos Koumenis, Andrew V. Kossenkov, Carlo Salas Salinas, Ioannis I. Verginadis, Nektaria Maria Leli, Ravi K. Amaravadi, Christine Polte, Paul P. Wang, Alexandra M Monroy, Davide Ruggero, J. Alan Diehl, Feven Tameire, Rani Ojha
Publikováno v:
Nature cell biology, vol 21, iss 7
Nature cell biology
Nature cell biology
The c-Myc oncogene drives malignant progression and induces robust anabolic and proliferative programmes leading to intrinsic stress. The mechanisms enabling adaptation to MYC-induced stress are not fully understood. Here we reveal an essential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f738c982d153fa8258254dd5ce12da
https://doi.org/10.1038/s41556-019-0347-9
https://doi.org/10.1038/s41556-019-0347-9
Autor:
Ioannis I. Verginadis, Harris Avgousti, James Monslow, Giorgos Skoufos, Frank Chinga, Kyle Kim, Nektaria Maria Leli, Ilias V. Karagounis, Brett I. Bell, Anastasia Velalopoulou, Carlo Salas Salinas, Victoria S. Wu, Yang Li, Jiangbin Ye, David A. Scott, Andrei L. Osterman, Arjun Sengupta, Aalim Weljie, Menggui Huang, Duo Zhang, Yi Fan, Enrico Radaelli, John W. Tobias, Florian Rambow, Panagiotis Karras, Jean-Christophe Marine, Xiaowei Xu, Artemis G. Hatzigeorgiou, Sandra Ryeom, J. Alan Diehl, Serge Y. Fuchs, Ellen Puré, Constantinos Koumenis
Publikováno v:
Nature cell biology. 24(6)
Bidirectional signalling between the tumour and stroma shapes tumour aggressiveness and metastasis. ATF4 is a major effector of the Integrated Stress Response, a homeostatic mechanism that couples cell growth and survival to bioenergetic demands. Usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374b585dbc21540d90e876209b13f267
https://pubmed.ncbi.nlm.nih.gov/35654838
https://pubmed.ncbi.nlm.nih.gov/35654838
Autor:
Nicholas Holdreith, Vemika Chandra, Carlo Salas Salinas, Grace Y Lee, Timothy S. Olson, Peter Nicholas, Wei Tong
Publikováno v:
Blood advances. 6(3)
Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment for a variety of hematological diseases. Allogenic HSCT requires hematopoietic stem cells (HSCs) from matched donors and comes with cytotoxicity and mortality. Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64ee4cb9f780910dc2365524e2818a2
https://pubmed.ncbi.nlm.nih.gov/34844262
https://pubmed.ncbi.nlm.nih.gov/34844262
Autor:
Nektaria Maria Leli, Souvik Dey, Lauren Brady, Carlo Salas Salinas, Jerome Lin, Giorgos Skoufos, Ioannis Verginadis, Artemis Chatzigeorgiou, Constantinos Koumenis
Publikováno v:
Cancer Research. 82:144-144
Tumor growth and metastasis involve a complex relationship with the tissue microenvironment. A proliferating tumor encounters several stresses from the microenvironment like hypoxia, lack of nutrients and acidosis. To cope with these conditions, canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23dd01ed61b7e8801c836fbbf878e6c3
https://doi.org/10.1158/1538-7445.am2022-144
https://doi.org/10.1158/1538-7445.am2022-144
Autor:
Ioannis Verginadis, Harris Avgousti, James Monslow, Giorgos Skoufos, Frank Chinga, Nektaria Maria Leli, Ilias Karagounis, Brett Bell, Carlo Salas Salinas, Yang Li, Jiangbin Ye, David Scott, Andrei Osterman, Arjun Sengupta, Aalim Weljie, Enrico Radaelli, John Tobias, Florian Rambow, Panagiotis Karras, Jean-Christophe Marine, Xiaowei Xu, Artemis Hatzigeorgiou, Sandra Ryeom, J Alan Diehl, Serge Fuchs, Ellen Pure', Constantinos Koumenis
ATF4 is a major effector of the Integrated Stress Response (ISR), a homeostatic mechanism coupling cell growth and survival to bioenergetic demands. Although the pro-tumorigenic role of the ISR in a tumor cell-intrinsic manner has been established, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce6f12c9365c81264086551773491cc
https://doi.org/10.21203/rs.3.rs-122088/v1
https://doi.org/10.21203/rs.3.rs-122088/v1
Interleukin 6 Signaling Blockade Exacerbates Acute and Late Injury From Focal Intestinal Irradiation
Autor:
Sravya Koduri, Ellen Puré, James Monslow, Edgar Ben-Josef, Carlo Salas Salinas, Brett Bell, Constantinos Koumenis, Ioannis I. Verginadis
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE: To evaluate the acute changes in leukocyte populations after focal irradiation and to assess the role of interleukin 6 (IL-6) in acute and late radiation injury. METHODS AND MATERIALS: Mice were surgically implanted with a radiopaque marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b303a788a944025921cf865094a1c789
https://europepmc.org/articles/PMC7699458/
https://europepmc.org/articles/PMC7699458/
Autor:
Nektaria Maria Leli, Frank Chinga, Christine Polte, Paul P. Wang, Davide Ruggero, Feven Tameire, Ioannis I. Verginadis, Alexandra M Monroy, Constantinos Koumenis, Crystal S. Conn, Weixuan Fu, Rani Ojha, J. Alan Diehl, Zoya Ignatova, Andrew V. Kossenkov, Serge Y. Fuchs, Jiangbin Ye, Ravi K. Amaravadi, Carlo Salas Salinas
Publikováno v:
Nature Cell Biology. 21:1052-1052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a123b4967d78b305f68c31eb172892bd
https://doi.org/10.1038/s41556-019-0370-x
https://doi.org/10.1038/s41556-019-0370-x