Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Carlo Sacchetti"'
Publikováno v:
Europe PubMed Central
The incidence of circulating colony-forming cells (CFU-C) and the ability of peripheral leucocytes to stimulate the colony formation (CSA) have been studied through a double layer agar culture system in 26 patients with neutrophilic leucocytosis and
Publikováno v:
Scopus-Elsevier
SUMMARY Human neutrophils, pre-exposed to low concentrations (1–10 ng/ml) of bacterial LPS in the presence of 1% autologous serum, released elastase activity in response to n-formyl-met-leu-phe (fMLP). Both cell incubation with LPS without subseque
Autor:
Patrizia Dapino, Alberto Ballestrero, Franco Dallegri, Luciano Ottonello, Fabio Ferrando, Franco Patrone, Carlo Sacchetti
Publikováno v:
Inflammation. 15:15-30
The lysis of tumor cells, and other nucleated mammalian cells, by neutrophilic polymorphonuclear leukocytes (PMNs) triggered by phorbol myristate acetate (PMA) represents a widely used model system to dissect the PMN cytolytic armamentarium, potentia
Publikováno v:
Clinical and experimental immunology. 94(3)
SUMMARY Human neutrophils, added to fibronectin (FN)-coated polystyrene wells and exposed to tumour necrosis factor-alpba (TNF-α, were found to exhibit a prolonged production of superoxide anion (Q2) after a lag period of approx 30 min. The O2 produ
Publikováno v:
Biochemical pharmacology. 42(12)
In the present study we have investigated the effect of six antibiotics (penicillin G, ceftazidime, cephotaxime, cephoperazon, ampicillin and piperacillin) on the neutrophil cytolytic activity by using a system constituted of phorbol-12-myristate-13-
Publikováno v:
Journal of Clinical Immunology. 4:439-444
Normal human neutrophils were found to destroy ox red blood-cell targets when incubated on micropore filters coated with aggregated IgG, as determined by the 51Cr release method. An intact neutrophil oxidative metabolism was essential for the cytotox
Publikováno v:
Scopus-Elsevier
Although neutrophils (neutrophilic polymorphonuclear leukocytes, PMNs) provide a principal means of host defense against bacteria and fungi, they can also promote host tissue injury in several non infectious diseases (1). The intervention of PMNs in
Autor:
Z.A. Karrar, Carlo Sacchetti, Ramon Estruch, Guido Frumento, M.J. Brown, Franco Dallegri, Loris Banchi, I. Melamed, H. Joshua, C. Llebaría, Itamar Raz, Franco Patrone, Reuven Or, G. Castaldi, M. Pastor, J.A. Murray, Aaron Polliack, U. Seligsohn, Alvaro Urbano-Márquez, G. Lupi, M. Djaldetti, F.A. Elseed, Rozman C, P.K. Mehrotra, Lawrence S. Lessin, Josep M. Grau, Eli Okon, Adrian Copplestone, D.N. Slater, Stuart Roath, G. Ricci, D. Bonetti, M. Masotti, Henri B. Weems, Rachel Leizerowitz
Publikováno v:
Acta Haematologica. 71:417-424
Publikováno v:
International Archives of Allergy and Immunology. 64:259-265
The effects of the sulphydryl group donor N-(2-mercaptopropionyl) glycine on neutrophil locomotion were evaluated in vitro. The drug, when used at a concentration of 10––3M was found to stimulate the random migration and chemotaxis of normal neut
Publikováno v:
Scopus-Elsevier
Leukaemic blast cells from 20 patients with acute leukaemia were examined for their capacity to mediate cytotoxicity against ox red blood cells in the presence of phorbol myristate acetate (PMA), a system widely employed as an in vitro model of tissu