Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Carlo Pifferi"'
Autor:
Roberto Fuentes, Leire Aguinagalde, Carlo Pifferi, Adrián Plata, Nagore Sacristán, Donatello Castellana, Juan Anguita, Alberto Fernández-Tejada
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Vaccine adjuvants are key for optimal vaccine efficacy, increasing the immunogenicity of the antigen and potentiating the immune response. Saponin adjuvants such as the carbohydrate-based QS-21 natural product are among the most promising candidates
Externí odkaz:
https://doaj.org/article/018e92f40a3a4cb9a97640b50ff5af60
Autor:
Carlo Pifferi, Leire Aguinagalde, Ane Ruiz-de-Angulo, Nagore Sacristán, Priscila Tonon Baschirotto, Ana Poveda, Jesús Jiménez-Barbero, Juan Anguita, Alberto Fernández-Tejada
Publikováno v:
Chemical Science. 14:3501-3513
The overexpression of aberrantly glycosylated tumor-associated mucin-1 (TA-MUC1) in human cancers makes it a major target for the development of anticancer vaccines derived from synthetic MUC1-(glyco) peptide antigens. However, glycopeptide-based sub
Autor:
Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, Carlo Pifferi, Vincent Aucagne
Site-selective, dual-conjugation approaches for the incorporation of distinct payloads are key for the development of molecularly targeted biomolecules, such as antibody conjugates, endowed with better properties. Combinations of cytotoxic drugs, ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbae085aa1a3f826aee4b28e0601c02
https://doi.org/10.26434/chemrxiv-2023-n578f
https://doi.org/10.26434/chemrxiv-2023-n578f
Publikováno v:
Nature Reviews. Chemistry
Nature Reviews Chemistry
Nature Reviews Chemistry
Modern subunit vaccines based on homogeneous antigens offer more precise targeting and improved safety compared with traditional whole-pathogen vaccines. However, they are also less immunogenic and require an adjuvant to increase the immunogenicity o
Autor:
Claire Tiertant, Alberto Fernández-Tejada, Nathalie Berthet, Ane Ruiz-de-Angulo, Diego Barriales, Juan Anguita, David Goyard, Nagore Sacristán, Olivier Renaudet, Carlo Pifferi
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2020, 11 (17), pp.4488-4498. ⟨10.1039/d0sc00544d⟩
Chemical Science, The Royal Society of Chemistry, 2020, 11 (17), pp.4488-4498. ⟨10.1039/d0sc00544d⟩
Tumor associated carbohydrate antigens (TACAs), such as the Tn antigen, have emerged as key targets for the development of synthetic anticancer vaccines. However, the induction of potent and functional immune responses has been challenging and, in mo
Autor:
Solène Gentil, Carlo Pifferi, Alan Le Goff, Pierre Rousselot-Pailley, Thierry Tron, Olivier Renaudet
Publikováno v:
Langmuir
Langmuir, 2021, 37 (3), pp.1001-1011. ⟨10.1021/acs.langmuir.0c02095⟩
Langmuir, American Chemical Society, 2021, 37 (3), pp.1001-1011. ⟨10.1021/acs.langmuir.0c02095⟩
Langmuir, 2021, 37 (3), pp.1001-1011. ⟨10.1021/acs.langmuir.0c02095⟩
Langmuir, American Chemical Society, 2021, 37 (3), pp.1001-1011. ⟨10.1021/acs.langmuir.0c02095⟩
International audience; Carbon nanotube electrodes were modified with ferrocene and laccase using two different click reactions strategies and taking advantage of bifunctional dendrimers and cyclopeptides. Using diazonium functionalization and the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e4eb66e4bac85a22061f4aff77693a
https://hal.science/hal-03132807/file/langmuir_final_HAL.pdf
https://hal.science/hal-03132807/file/langmuir_final_HAL.pdf
Autor:
Corinne Vivès, Vanessa Porkolab, Anna Bernardi, Carlo Pifferi, Ieva Sutkeviciute, Marwa Taouai, Olivier Renaudet, Michel Thépaut, Franck Fieschi, Mohammed Benazza, Stefania Ordanini
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18 (25), pp.4763-4772. ⟨10.1039/d0ob00781a⟩
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2020, 18 (25), pp.4763-4772. ⟨10.1039/d0ob00781a⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18 (25), pp.4763-4772. ⟨10.1039/d0ob00781a⟩
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2020, 18 (25), pp.4763-4772. ⟨10.1039/d0ob00781a⟩
International audience; Multivalent interactions between complex carbohydrates and oligomeric C-type lectins govern a wide range of immune responses. Up to date, standard SPR (surface plasmon resonance) competitive assays have largely been to evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79468965490138b854df077aae98ec4
https://hal.archives-ouvertes.fr/hal-02934459
https://hal.archives-ouvertes.fr/hal-02934459
Autor:
Corinne Vivès, Vanessa Porkolab, Ieva Sutkeviciute, Marwa Taouai, Franck Fieschi, Olivier Renaudet, Mohammed Benazza, Anna Bernardi, Stefania Ordanini, Carlo Pifferi, Michel Thépaut
Multivalent interactions between complex carbohydrates and oligomeric C-type lectins govern a wide range of immune responses. Up to date, standard SPR (surface plasmon resonance) competitive assays have largely been to evaluate binding properties fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f68bf51cbf8d2d99ed57dc8cd058ef4
Publikováno v:
Nature Reviews Chemistry. 5:361-361
Autor:
Lara K. Mahal, Anne Imberty, William Pau, João P. Ribeiro, Annabelle Varrot, Olivier Renaudet, Carlo Pifferi
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2016, 473 (14), pp.2109-2118. ⟨10.1042/BCJ20160340⟩
Biochemical Journal, Portland Press, 2016, 473 (14), pp.2109-2118. ⟨10.1042/BCJ20160340⟩
CBMs (carbohydrate-binding modules) are a class of polypeptides usually associated with carbohydrate-active enzymatic sites. We have characterized a new member of the CBM40 family, coded from a section of the gene NanI from Clostridium perfringens .