Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carlo N. G. Giachello"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The emergence of coordinated network function during nervous system development is often associated with critical periods. These phases are sensitive to activity perturbations during, but not outside, of the critical period, that can lead to
Externí odkaz:
https://doaj.org/article/29e075c889904dd6829db8ff6d285137
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 2, Pp 141-150 (2017)
Epilepsy is a significant disorder for which approximately one-third of patients do not respond to drug treatments. Next-generation drugs, which interact with novel targets, are required to provide a better clinical outcome for these individuals. To
Externí odkaz:
https://doaj.org/article/5456cede842b4ea5a02e881bc6b2b388
Understanding how the brain encodes behaviour is the ultimate goal of neuroscience and the ability to objectively and reproducibly describe and quantify behaviour is a necessary milestone on this path. Recent progresses in machine learning and comput
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750b0e79339ae2d76f79a8d33b3ec22b
https://doi.org/10.7554/elife.86695
https://doi.org/10.7554/elife.86695
Understanding how the brain encodes behaviour is the ultimate goal of neuroscience and the ability to objectively and reproducibly describe and quantify behaviour is a necessary milestone on this path. Recent progresses in machine learning and comput
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e753ee12089b6f759eb9d66d4b6577d1
https://doi.org/10.1101/2022.12.15.519769
https://doi.org/10.1101/2022.12.15.519769
Autor:
Fergus Gerard Paul Earley, Kathryn S. Lilley, Steven Russell, Benedict Dirnberger, Michael J. Deery, Dagmara Korona, David-Paul Minde, Glynnis Johnson, Carlo N. G. Giachello, Karin H. Müller, Lucy C. Firth, Rayner M. L. Queiroz
Drosophila nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that represent a target for insecticides. Peptide neurotoxins are known to block nAChRs by binding to their target subunits, however, a better understanding of recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3132072ef7394968f5f00c53ac440c12
https://doi.org/10.1101/2021.08.13.456240
https://doi.org/10.1101/2021.08.13.456240
Autor:
Roman, Praschberger, Simon A, Lowe, Nancy T, Malintan, Carlo N G, Giachello, Nian, Patel, Henry, Houlden, Dimitri M, Kullmann, Richard A, Baines, Maria M, Usowicz, Shyam S, Krishnakumar, James J L, Hodge, James E, Rothman, James E C, Jepson
Publikováno v:
Cell Reports
Summary Mutations in the Golgi SNARE (SNAP [soluble NSF attachment protein] receptor) protein Membrin (encoded by the GOSR2 gene) cause progressive myoclonus epilepsy (PME). Membrin is a ubiquitous and essential protein mediating ER-to-Golgi membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7609e8b4e1cb0f044c42dc82d700fb40
https://pubmed.ncbi.nlm.nih.gov/28978487
https://pubmed.ncbi.nlm.nih.gov/28978487
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(42)
Many animals are able to sense the Earth's geomagnetic field to enable behaviors such as migration. It is proposed that the magnitude and direction of the geomagnetic field modulates the activity of cryptochrome (CRY) by influencing photochemical rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c04a051ab9df1062db1941c885914eb
https://pubmed.ncbi.nlm.nih.gov/27798129
https://pubmed.ncbi.nlm.nih.gov/27798129