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pro vyhledávání: '"Carlo M. Malabanan"'
Autor:
Ian M. Williams, Ethan S. McClain, Peter C. Lord, Justin M. Gregory, Freyja D. James, David E. Cliffel, P. Mason McClatchey, Carlo M. Malabanan, David H. Wasserman
Publikováno v:
Diabetes
Continuous glucose monitor (CGM) readings are delayed relative to blood glucose, and this delay is usually attributed to the latency of interstitial glucose levels. However, CGM-independent data suggest rapid equilibration of interstitial glucose. Th
Autor:
Yolanda F. Otero, Kimberly X. Mulligan, David H. Wasserman, Haihong Zong, Jeffrey E. Pessin, Tammy M. Barnes, Eric A. Ford, Owen P. McGuinness, Carlo M. Malabanan
Lipopolysaccharide (LPS) is known to impair insulin stimulated muscle glucose uptake. We determined if increased glucose transport (GLUT4) or phosphorylation capacity (hexokinase II; HKII) could overcome the impairment in muscle glucose uptake (MGU).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24165c49d03ef752bd5cc337e879fe16
https://europepmc.org/articles/PMC4868638/
https://europepmc.org/articles/PMC4868638/
Autor:
Daryl K. Granner, R. Richard Pencek, Carlo M. Malabanan, Patrick T. Fueger, David H. Wasserman, Deanna P. Bracy
Publikováno v:
Diabetes. 53:306-314
The aim of the present study was to determine the specific sites of impairment to muscle glucose uptake (MGU) in the insulin-resistant high-fat-fed, conscious C57BL/6J mouse. Wild type (WT) and hexokinase II overexpressing (HK(Tg)) mice were fed eith
Autor:
Deanna P. Bracy, R. Richard Pencek, Patrick T. Fueger, David H. Wasserman, Carlo M. Malabanan
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 286:E77-E84
Muscle glucose uptake (MGU) is determined by glucose delivery, transport, and phosphorylation. C57Bl/6J mice overexpressing GLUT4, hexokinase II (HK II), or both were used to determine the barriers to MGU. A carotid artery and jugular vein were cathe
Autor:
Owen P. McGuinness, David H. Wasserman, Tasneem Ansari, Julio E. Ayala, Patrick T. Fueger, Deanna P. Bracy, Carlo M. Malabanan, Freyja D. James
Publikováno v:
Journal of Visualized Experiments : JoVE
Type 2 diabetes is characterized by a defect in insulin action. The hyperinsulinemic-euglycemic clamp, or insulin clamp, is widely considered the "gold standard" method for assessing insulin action in vivo. During an insulin clamp, hyperinsulinemia i
Autor:
Deanna P. Bracy, Yolanda F. Otero, Kimberly X. Mulligan, Owen P. McGuinness, Carlo M. Malabanan
Publikováno v:
The FASEB Journal. 23
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 291(6)
Previous studies in mice suggest that portal venous infusion of glucose at a low rate paradoxically causes hypoglycemia; this does not occur in dogs, rats, and humans. A possible explanation is that fasting status in the mouse studies may have altere
Autor:
Carlo M. Malabanan, Deanna P. Bracy, David H. Wasserman, R. Richard Pencek, Sami Heikkinen, Patrick T. Fueger, Markku Laakso
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 285(5)
Muscle glucose uptake (MGU) is distributively controlled by three serial steps: delivery of glucose to the muscle membrane, transport across the muscle membrane, and intracellular phosphorylation to glucose 6-phosphate by hexokinase (HK). During stat