Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carlo J. Gambone"'
Autor:
Azriel Schmidt, Michael Chisamore, Carlo J. Gambone, Gregory Michael Dillon, Stephen E. Alves, Matthew Baran, Sean Riley, Michael A. Gentile, Osvaldo A. Flores, Hilary A. Wilkinson
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 163:88-97
The androgen receptor (AR) is a member of the nuclear hormone receptor super family of transcription factors. Androgens play an essential role in the development, growth, and maintenance of male sex organs, as well as the musculoskeletal and central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf3b55a2b4a148ba02ec5fe23452a36
https://doi.org/10.1016/j.jsbmb.2016.04.007
https://doi.org/10.1016/j.jsbmb.2016.04.007
Autor:
William J. Ray, Chang Bai, Stephen E. Alves, Tara E. Cusick, Brenda L Pennypacker, Evan E. Opas, Michael J. Chisamore, Carlo J. Gambone, Damien Ferraro, David J. Bettoun, Azriel Schmidt, Hilary A. Wilkinson, Angela Scafonas, Michael A. Gentile, Osvaldo A. Flores, Paul Hodor, Meissner Robert S, James J. Perkins
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 143:29-39
Prostate cancer (PCa) initially responds to inhibition of androgen receptor (AR) signaling, but inevitably progresses to hormone ablation-resistant disease. Much effort is focused on optimizing this androgen deprivation strategy by improving hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05fa5f1d9ca8a07a5b1af5c4fa5cd5b
https://doi.org/10.1016/j.jsbmb.2014.02.005
https://doi.org/10.1016/j.jsbmb.2014.02.005
Autor:
Azriel Schmidt, Chang Bai, Angela Scafonas, Carlo J. Gambone, Su Jane Rutledge, Leonard P. Freedman, Sheila McElwee-Witmer, Robert L. Vogel, Paul Hodor, Oliver Chen, David J. Bettoun
Publikováno v:
Journal of Biological Chemistry. 280:38898-38901
Signaling by androgens and interferons (IFN) plays an important role in prostate cancer initiation and progression. Using microarray analysis, we describe here a functional cross-talk between dihydrotestosterone and interferon signaling. Glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5692f5bc828d9948e2af45e8e779eef
https://doi.org/10.1074/jbc.c500324200
https://doi.org/10.1074/jbc.c500324200
Autor:
Kristin Knecht, Chang Bai, Chih-Tai Leu, Shun-ichi Harada, H. Zhang, Angela Scafonas, Azriel Schmidt, Alfred A. Reszka, Su Jane Rutledge, Leonard P. Freedman, Fang Chen, Carlo J. Gambone, Robert L. Vogel, Viera Kasparcova
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 91:247-257
Androgens play important endocrine roles in development and physiology. Here, we characterize activities of two “Andro” prohormones, androstenedione (A-dione) and 4-androsten-3β,17β-diol (A-diol) in MDA-MB-453 (MDA) and LNCaP cells. A-dione and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a327d0fadfedebd13626c322b8592b
https://doi.org/10.1016/j.jsbmb.2004.04.009
https://doi.org/10.1016/j.jsbmb.2004.04.009
Autor:
Richard L. Beard, Kenneth J. Soprano, Jerome L. Gabriel, Juliet M. Hutcheson, Carlo J. Gambone, Dianne Robert Soprano, Roshantha A.S. Chandraratna
Publikováno v:
Molecular Pharmacology. 61:334-342
Potential pharmacological applications in the areas of oncology, dermatology, diabetes, and atherosclerosis of synthetic analogs of retinoic acid that target a specific nuclear receptor and/or biological response have generated great interest in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee75fb1bb979a5453cd5aa4e9eaf2e9
https://doi.org/10.1124/mol.61.2.334
https://doi.org/10.1124/mol.61.2.334
Autor:
Kenneth J. Soprano, Roshantha A.S. Chandraratna, Jerome L. Gabriel, Sabina N. Sheikh, Carlo J. Gambone, Dianne Robert Soprano, D. M. Kochhar
Publikováno v:
Toxicology and Applied Pharmacology. 174:153-159
The synthetic retinoid AGN 193109 is a potent pan retinoic acid receptor (RAR) antagonist. Treatment of pregnant mice with a single oral 1 mg/kg dose of this antagonist on day 8 postcoitum results in severe craniofacial (median cleft face or frontona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548cc7755c91ccc82de591372b5a4075
https://doi.org/10.1006/taap.2001.9209
https://doi.org/10.1006/taap.2001.9209
Autor:
Jerome L. Gabriel, Zeng-Ping Zhang, Kenneth J. Soprano, Dianne Robert Soprano, Muna Shukri, Carlo J. Gambone
Publikováno v:
Archives of Biochemistry and Biophysics. 380:339-346
The biological actions of retinoic acid (RA) are mediated by retinoic acid receptors (RARalpha, -beta, and -gamma) and retinoid X receptors (RXRalpha, -beta, and -gamma). Although the ligand-binding domains of RARs and RXRs have been suggested to sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be63ae2cc1bb42a0f3cb85c564fad0e
https://doi.org/10.1006/abbi.2000.1932
https://doi.org/10.1006/abbi.2000.1932
Autor:
Zhen Ping Zhang, Jerome L. Gabriel, Carlo J. Gambone, Christopher L. Wolfgang, Kenneth J. Soprano, Dianne Robert Soprano
Publikováno v:
Journal of Biological Chemistry. 273:34016-34021
The diverse biological actions of retinoic acid (RA) are mediated by retinoic acid receptors (RARalpha, beta and gamma) and retinoid X receptors (RXR alpha, beta, and gamma). Although the ligand-binding domains of RARs share the same novel folding pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c738256d244203d915c2b74e8f182751
https://doi.org/10.1074/jbc.273.51.34016
https://doi.org/10.1074/jbc.273.51.34016
Autor:
Peter Szczerba, Danielle H. Euler, John E. Fisher, Azriel Schmidt, Kenneth D. Anderson, Philip E. Brandish, Milenko Cicmil, Halea A. Corcoran, Alan Byford, Amy Musselman, Nelly A. Kuklin, Chi-Sung Chiu, Meissner Robert S, Robert L. Vogel, John H. Shin, Charles D. Thompson, Helen J. Mitchell, Sudha Warrier, Traci Q. Lifsted, Catherine Tribouley, Sheila McElwee-Witmer, Carlo J. Gambone, Gretchen A. Baltus, John Miao, Ian McIntosh, James C. Hershey, Chang Bai, Patricia B. Bunting, Martha Hasbun-Manning, Elizabeth Landis, Christopher J. Bungard
Publikováno v:
European journal of pharmacology. 724
Glucocorticoids are used widely in the treatment of inflammatory diseases, but use is accompanied by a significant burden of adverse effects. It has been hypothesized that gene- and cell-specific regulation of the glucocorticoid receptor by small mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1060d950b3eafcd26afc92fdc4fa2f6a
https://pubmed.ncbi.nlm.nih.gov/24374007
https://pubmed.ncbi.nlm.nih.gov/24374007