Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Carlo Iavarone"'
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 9, Pp 871-881 (2017)
Introduction: The present review summarizes the growing body of work defining the mechanisms of action of this exciting new vaccine technology that should allow rational approaches in the design of next generation mRNA vaccines. Areas covered: Bio-di
Externí odkaz:
https://doaj.org/article/af0fd2c6700e471485016843d9b2aaab
Autor:
Farid Sari-Sarraf, Gillis R. Otten, Timothy Pepini, Thomas Carsillo, Carlo Iavarone, Jeffrey B. Ulmer, Dong Yu, Alicia L. Carlson, Giulietta Maruggi, Jason C. Debasitis, Katrin Ramsauer, Anne-Marie Pulichino, Andrew Geall
Publikováno v:
The Journal of Immunology. 198:4012-4024
RNA-based vaccines have recently emerged as a promising alternative to the use of DNA-based and viral vector vaccines, in part because of the potential to simplify how vaccines are made and facilitate a rapid response to newly emerging infections. SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bb56454b7ca4b588da1373c4fa5482
https://doi.org/10.4049/jimmunol.1601877
https://doi.org/10.4049/jimmunol.1601877
Autor:
Federica Piccioni, Carlo Iavarone, David Colecchia, Matteo Rossi, Arturo Verrotti di Pianella, Angela Strambi, Mario Chiariello
Publikováno v:
Journal of Biological Chemistry. 286:8507-8522
ERK8 (MAPK15) is a large MAP kinase already implicated in the regulation of the functions of different nuclear receptors and in cellular proliferation and transformation. Here, we identify ERRα as a novel ERK8-interacting protein. As a consequence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f81bedf6adae1722a81ac522f4512e
https://doi.org/10.1074/jbc.m110.179523
https://doi.org/10.1074/jbc.m110.179523
Autor:
Mario Chiariello, Rosa Marina Melillo, Massimo Santoro, Francesca Carlomagno, Carlo Iavarone, Stella M. Carlomagno, Mario Acunzo, Annunziata Catania
Publikováno v:
Journal of Biological Chemistry. 281:10567-10576
Mitogen-activated protein (MAP) kinases have a central role in several biological functions, including cell adhesion and spreading, chemotaxis, cell cycle progression, differentiation, and apoptosis. Extracellular signal-regulated kinase 8 (Erk8) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567ec84353833786892f71ae9a4006a0
https://doi.org/10.1074/jbc.m513397200
https://doi.org/10.1074/jbc.m513397200
Autor:
James J. Vincent, Giuliana Salvatore, Paul H. Duray, Tapan K. Bera, Byungkook Lee, Carlo Iavarone, Vasantha Kumar, Ira Pastan, B. K. Sathyanarayana, Rangan Maitra
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3058-3063
To identify target antigens for prostate cancer therapy, we have combined computer-based screening of the human expressed sequence tag database and experimental expression analysis to identify genes that are expressed in normal prostate and prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18275ec57ecf6950e1e43e8e5be96307
https://doi.org/10.1073/pnas.052713699
https://doi.org/10.1073/pnas.052713699
Autor:
Laura Fontana, Carlo Iavarone, M. Patrizia Stoppelli, M.Vittoria Barone, Ferdinando Chiaradonna, Glen M. Scholz, M.Vincenza Carriero
Publikováno v:
The EMBO Journal. 18:3013-3023
Anchorage-independent myelomonocytic cells acquire adherence within minutes of differentiation stimuli, such as the proteolytically inactive N-terminal fragment of urokinase binding to its cognate glycosylphosphatidylinositol (GPI)-anchored receptor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faddff054e59ad3c29499844f2334d4
https://doi.org/10.1093/emboj/18.11.3013
https://doi.org/10.1093/emboj/18.11.3013
Autor:
Ferdinando Chiaradonna, M. Luisa Nolli, Anna Brandazza, Carlo Iavarone, Ciro Iaccarino, M. Patrizia Stoppelli, M. Rosaria Mastronicola, Paola Franco
Publikováno v:
The Journal of Cell Biology
Serine phosphorylation of human pro-urokinase (pro-uPA) by A431 human carcinoma cells results in a catalytically active molecule with reduced sensitivity to plasminogen activator inhibitor type 1. We mapped the phosphorylated seryl residues by analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eca6c57e60eb4220bdd98a6cb6bbec
https://doi.org/10.1083/jcb.137.3.779
https://doi.org/10.1083/jcb.137.3.779
Autor:
Angela Strambi, Mario Chiariello, Arturo Verrotti di Pianella, Carlo Iavarone, Federica Piccioni, David Colecchia, Matteo Rossi, Sveva Sanzone, Claudia Dall'Armi
Publikováno v:
Autophagy
Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved catabolic process necessary for normal recycling of cellular constituents and for appropriate response to cellular stress. Although several genes belonging to the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84aa91bb4165ae920a7524018ee88e5c
https://pubmed.ncbi.nlm.nih.gov/22948227
https://pubmed.ncbi.nlm.nih.gov/22948227
Autor:
Gillis R. Otten, M. Lamine Mbow, Owen M. Siggs, Bruce Beutler, Alexander N.R. Weber, Nicholas Valiante, Katrin Ramsauer, Pu Zhang, Jason C. Debasitis, Andriy V. Kubarenko, Igor Leykin, Ugo D'Oro, Carlo Iavarone, Alberto Visintin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(7)
TLR7 is the mammalian receptor for ssRNA and some nucleotide-like small molecules. We have generated a mouse by N-nitrose-N′-ethyl urea mutagenesis in which threonine 68 of TLR7 was substituted with isoleucine. Cells bearing this mutant TLR7 lost t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607dcb496a51edf3f1b6f2ede957a070
http://ora.ox.ac.uk/objects/uuid:a49fe24a-4be7-4aa7-90bd-af567412dabc
http://ora.ox.ac.uk/objects/uuid:a49fe24a-4be7-4aa7-90bd-af567412dabc
Publikováno v:
ChemInform. 24
The hydroxymercuration (OM) reaction of nonconjugated diene system of aucubin (1) with at least 2 equivalents of Hg(II) salts involved not only the enol ether Δ 3 double bond, but also the less reactive Δ 7 cyclopentene double bond; the unique inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c0cd8134d04c30736b2055ab801645
https://doi.org/10.1002/chin.199330124
https://doi.org/10.1002/chin.199330124