Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carlo De Donno"'
Autor:
Mohammad Lotfollahi, Anna Klimovskaia Susmelj, Carlo De Donno, Leon Hetzel, Yuge Ji, Ignacio L Ibarra, Sanjay R Srivatsan, Mohsen Naghipourfar, Riza M Daza, Beth Martin, Jay Shendure, Jose L McFaline‐Figueroa, Pierre Boyeau, F Alexander Wolf, Nafissa Yakubova, Stephan Günnemann, Cole Trapnell, David Lopez‐Paz, Fabian J Theis
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 6, Pp 1-19 (2023)
Abstract Recent advances in multiplexed single‐cell transcriptomics experiments facilitate the high‐throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally u
Externí odkaz:
https://doaj.org/article/418ea36376f0413cb228551ff196f2db
Autor:
Carlo De Donno, Soroor Hediyeh-Zadeh, Marco Wagenstetter, Amir Ali Moinfar, Luke Zappia, Mohammad Lotfollahi, Fabian J. Theis
The increasing generation of population-level single-cell atlases with hundreds or thousands of samples has the potential to link demographic and technical metadata with high-resolution cellular and tissue data in homeostasis and disease. Constructin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f02a2c69e89e1cbabf1ec54c6973a0
https://doi.org/10.1101/2022.11.28.517803
https://doi.org/10.1101/2022.11.28.517803
Autor:
Malte Luecken, Lisa Sikkema, Daniel Strobl, Luke Zappia, Elo Madissoon, Nikolay Markov, Laure-Emmanuelle Zaragosi, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Christophe Becavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-i Chung, Antoine Collin, Aurore Gay, Baharak Hooshiar Kashani, Manu Jain, Theodore Kapellos, Tessa Kole, Christoph Mayr, Michael von Papen, Lance Peter, Ciro Ramírez-Suástegui, Janine Schniering, Chase Taylor, Thomas Walzthoeni, Chuan Xu, Linh Bui, Carlo de Donno, Leander Dony, Minzhe Guo, Austin Gutierrez, Lukas Heumos, Ni Huang, Ignacio Ibarra Del Río, Nathan Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-Lopez, Kyle Travaglini, Anna Wilbrey-Clark, Kaylee Worlock, Masahiro Yoshida, Tushar Desai, Orit Rozenblatt-Rosen, Christine Falk, Naftali Kaminski, Mark Krasnow, Robert Lafyatis, Marko Nikolic, Joseph Powell, Jay Rajagopal, Max Seibold, Dean Sheppard, Douglas Shepherd, Sarah Teichmann, Alexander Tsankov, Jeffrey Whitsett, Yan Xu, Nicholas Banovich, Pascal Barbry, Thu Duong, Kerstin Meyer, Jonathan Kropski, Dana Pe'er, Herbert Schiller, Purushothama Rao Tata, Joachim Schultze, Maarten van den Berge, Yuexin Chen, James Hagood, Ahmed Hassan, Peter Horvath, Joakim Lundeberg, Sylvie Leroy, Charles Marquette, Gloria Pryhuber, Christos Samakovlis, Xin Sun, Lorraine Ware, Kun Zhang, Alexander Misharin, Martijn Nawijn, Fabian Theis
Organ- and body-scale cell atlases have the potential to transform our understanding of human biology. To capture the variability present in the population, these atlases must include diverse demographics such as age and ethnicity from both healthy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c225b8ec842494e3c796c31c793715c
https://doi.org/10.21203/rs.3.rs-1438584/v1
https://doi.org/10.21203/rs.3.rs-1438584/v1
Autor:
Juan Pablo Lopez, Malte D. Lücken, Elena Brivio, Stoyo Karamihalev, Aron Kos, Carlo De Donno, Asaf Benjamin, Huanqing Yang, Alec L.W. Dick, Rainer Stoffel, Cornelia Flachskamm, Andrea Ressle, Simone Roeh, Rosa-Eva Huettl, Andrea Parl, Carola Eggert, Bozidar Novak, Yu Yan, Karin Yeoh, Maria Holzapfel, Barbara Hauger, Daniela Harbich, Bianca Schmid, Rossella Di Giaimo, Christoph W. Turck, Mathias V. Schmidt, Jan M. Deussing, Matthias Eder, Julien Dine, Fabian J. Theis, Alon Chen
A single sub-anesthetic dose of ketamine produces a rapid and sustained antidepressant response, yet the molecular mechanisms responsible for this remain unclear. Here, we identified cell-type-specific transcriptional signatures associated with a sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cd49786fe8c5bfdb8836783f07ac71
http://hdl.handle.net/11588/891105
http://hdl.handle.net/11588/891105
Autor:
Ignacio L. Ibarra, Yuge Ji, Anna Klimovskaia Susmelj, David Lopez-Paz, Nafissa Yakubova, Fabian J. Theis, F. Alexander Wolf, Carlo De Donno, Mohammad Lotfollahi
Recent advances in multiplexed single-cell transcriptomics experiments are facilitating the high-throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally unfeasib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceabde4e009ed574284dfd6ace6a95a8
https://doi.org/10.1101/2021.04.14.439903
https://doi.org/10.1101/2021.04.14.439903
Autor:
Felix Beuschlein, Charles B. Nemeroff, Max L. Pöhlmann, Fabian J. Theis, Mathias V. Schmidt, Anna Riester, W. Edward Craighead, Martin Fassnacht, Rainer Stoffel, Cynthia L. Andoniadou, Tanja Brückl, Clara Engelhardt, Elena Brivio, Carlo De Donno, Helen S. Mayberg, Nicolas Rost, Martin Reincke, Alina Tontsch, Miriam Peters, Javier M. Villamizar, Darina Czamara, Alon Chen, Aron Kos, Andrea Ressle, Boadie W. Dunlop, Juan Pablo Lopez, Alice Santambrogio, Elisabeth B. Binder, Simone Roeh, Silviu Sbiera
Publikováno v:
Science Advances
Dissection of the HPA axis using single-cell RNA sequencing uncovers adrenal ABCB1 as an important player of stress adaptation.
Chronic activation and dysregulation of the neuroendocrine stress response have severe physiological and psychologica
Chronic activation and dysregulation of the neuroendocrine stress response have severe physiological and psychologica