Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carlo Cusi"'
Autor:
Giovanni Carapezza, Carlo Cusi, Ettore Rizzo, Laura Raddrizzani, Sebastiano Di Bella, Alessio Somaschini, Antonella Leone, Rosita Lupi, Margherita Mutarelli, Vincenzo Nigro, Diego di Bernardo, Paolo Magni, Antonella Isacchi, Roberta Bosotti
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Protein kinases are enzymes controlling different cellular functions. Genetic alterations often result in kinase dysregulation, making kinases a very attractive class of druggable targets in several human diseases. Existing approv
Externí odkaz:
https://doaj.org/article/a92baa76a04346bf8b7c7872513455a7
Autor:
Roberta Bosotti, Paola Magnaghi, Sebastiano Di Bella, Liviana Cozzi, Carlo Cusi, Fabio Bozzi, Nicola Beltrami, Giovanni Carapezza, Dario Ballinari, Nadia Amboldi, Rosita Lupi, Alessio Somaschini, Laura Raddrizzani, Barbara Salom, Arturo Galvani, Silvia Stacchiotti, Elena Tamborini, Antonella Isacchi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Chordomas are rare, slowly growing tumors with high medical need, arising in the axial skeleton from notochord remnants. The transcription factor “brachyury” represents a distinctive molecular marker and a key oncogenic driver of chordom
Externí odkaz:
https://doaj.org/article/2e2d8fd735034e6896516334379601fa
Autor:
Ettore Rizzo, Vincenzo Nigro, Alessio Somaschini, Sebastiano Di Bella, Antonella Leone, Margherita Mutarelli, Giovanni Carapezza, Diego di Bernardo, Laura Raddrizzani, Roberta Bosotti, Rosita Lupi, Antonella Isacchi, Carlo Cusi, Paolo Magni
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
BMC Genomics
BMC Genomics
Background Protein kinases are enzymes controlling different cellular functions. Genetic alterations often result in kinase dysregulation, making kinases a very attractive class of druggable targets in several human diseases. Existing approved drugs
Autor:
Laura Raddrizzani, Antonella Leone, Giovanni Carapezza, Carlo Cusi, Alessio Somaschini, Sebastiano Di Bella, Antonella Isacchi, Tommaso Mazza, Roberta Bosotti
Publikováno v:
Scientific Data
Inhibition of kinase gene fusions (KGFs) has proven successful in cancer treatment and continues to represent an attractive research area, due to kinase druggability and clinical validation. Indeed, literature and public databases report a remarkable
Autor:
Fabio Bozzi, Nicola Beltrami, Roberta Bosotti, Rosita Lupi, Barbara Salom, Nadia Amboldi, Giovanni Carapezza, Arturo Galvani, Silvia Stacchiotti, Paola Magnaghi, Elena Tamborini, Liviana Cozzi, Dario Ballinari, Carlo Cusi, Antonella Isacchi, Alessio Somaschini, Sebastiano Di Bella, Laura Raddrizzani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Chordomas are rare, slowly growing tumors with high medical need, arising in the axial skeleton from notochord remnants. The transcription factor “brachyury” represents a distinctive molecular marker and a key oncogenic driver of chordomas. Tyros
Autor:
Gaia Roversi, Clizia Chinello, Vittorio Giardini, Fulvio Magni, Mattia Garancini, Gabriele De Sio, Fabio Pagni, Cristina Arosio, Veronica Mainini, Paola Caria, Carlo Cusi, Roberta Vanni
Publikováno v:
Endocrine Pathology. 24:250-253
To the Editor, Many different molecular techniques (polymerase chain reaction (PCR), DNA sequencing, fluorescence in situ hybridization (FISH)) have been introduced in thyroid pathology [1]. Fewer studies evaluated the role of proteomic analysis in t
Autor:
Nadia Amboldi, Silvana Pilotti, Elena Conca, Silvia Stacchiotti, Antonella Isacchi, Fabio Bozzi, Liviana Cozzi, Alessio Somaschini, Sebastiano Di Bella, Paola Magnaghi, Arturo Galvani, Carlo Cusi, Dario Ballinari, Barbara Salom, Marco A. Pierotti, Elena Tamborini, Roberta Bosotti
Publikováno v:
Cancer Research. 75:74-74
Chordomas are rare, slowly growing but locally invasive bone tumors, derived from notocord remnants and characterized by the expression of “Brachyury” transcription factor. No standard medical therapy is available for this indication that is resi