rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer.

Autor: Bríd M Ryan, Andrew C McClary, Nicola Valeri, Dillon Robinson, Alessio Paone, Elise D Bowman, Ana I Robles, Carlo Croce, Curtis C Harris

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36306 (2012)

Colorectal cancer is the third most incident cancer and cause of cancer-related death in the United States. MicroRNAs, a class of small non-coding RNAs, have been implicated in the pathogenesis and prognosis of colorectal cancer, although few studies

Externí odkaz: https://doaj.org/article/d6bb425dd9324e18834506f8c437c3bb

A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis

Autor: Dario Palmieri, Marina Capece, Anna Tessari, Joseph Mills, Gian Luca Rampioni Vinciguerra, Chenyu Lin, Bryan McElwain, Wayne Miles, Vincenzo Coppola, Carlo Croce

The OsTIR1/auxin-inducible degron (AID) system allows selective protein degradation upon exposure to the phytohormone auxin. However, this technology does not allow to study the effect of acute protein depletion selectively in one phase of the cell c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abaff8fe210e3f6a1611113f620e6db4
https://doi.org/10.21203/rs.3.rs-584199/v1

Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells

Autor: Michela Garofalo, Danilo Fiore, P De Marinis, Margherita Iaboni, Giulia Romano, Giuseppina Roscigno, Gerolama Condorelli, Cristina Quintavalle, Elvira Donnarumma, Carlo Croce

Publikováno v: Oncogene (Basingstoke) (2012).
info:cnr-pdr/source/autori:Quintavalle C, Donnarumma E, Iaboni M, Roscigno G, Garofalo M, Romano G, Fiore D, De Marinis P, Croce CM, Condorelli G./titolo:Effect of miR-21 and miR-30b%2Fc on TRAIL-induced apoptosis in glioma cells./doi:/rivista:Oncogene (Basingstoke)/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

Glioblastoma is the most frequent brain tumor in adults and is the most lethal form of human cancer. Despite the improvements in treatments, survival of patients remains poor. To define novel pathways that regulate susceptibility to tumor necrosis fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f30d5380d1c41bcb722e13bae76ba0
https://doi.org/10.1038/onc.2012.410

MicroRNAs and chromosomal abnormalities in cancer cells

Autor: Carlo Croce, George A. Calin

Publikováno v: Oncogene. 25:6202-6210

Over the past five decades, a plethora of nonrandom chromosomal abnormalities have been consistently reported in malignant cells facilitating the identification of cancer-associated protein coding oncogenes and tumor suppressors. The genetic dissecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2134ecb26485bcfc2433c447f647ba
https://doi.org/10.1038/sj.onc.1209910

Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax

Autor: Eli Canaani, Kay Huebner, R Rallapalli, Hansjuerg Alder, Y Sedkov, Alexander Mazo, R Prasad, Teresa Druck, T Yano, Florencia Bullrich, A B Zhadanov, Carlo Croce

Publikováno v: Oncogene. 15:549-560

The ALL-1 gene is involved in human acute leukemia through chromosome translocations or internal rearrangements. ALL-1 is the human homologue of Drosophila trithorax. The latter is a member of the trithorax group (trx-G) genes which together with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0704d0370c605671121166363b276267
https://doi.org/10.1038/sj.onc.1201211