Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Carlo Contoreggi"'
Autor:
Hiroto Kuwabara, Stephen J Heishman, James R Brasic, Carlo Contoreggi, Nicola Cascella, Kristen M Mackowick, Richard Taylor, Olivier Rousset, William Willis, Marilyn A Huestis, Marta Concheiro, Gary Wand, Dean F Wong, Nora D Volkow
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113694 (2014)
The rewarding effects of nicotine are associated with activation of nicotine receptors. However, there is increasing evidence that the endogenous opioid system is involved in nicotine's rewarding effects. We employed PET imaging with [11C]carfentanil
Externí odkaz:
https://doaj.org/article/f479d7c7614a4c96b3cf3dc1c06a8f27
Publikováno v:
Neurobehavioral HIV medicine
Pathologic stress (distress) disturbs immune, cardiovascular, metabolic, and behavioral homeostasis. Individuals living with HIV and those at risk are vulnerable to stress disorders. Corticotropin-releasing hormone (CRH) is critical in neuroendocrine
Autor:
Carlo Contoreggi
Publikováno v:
Nuclear Medicine and Biology. 42:323-339
The stress system provides integration of both neurochemical and somatic physiologic functions within organisms as an adaptive mechanism to changing environmental conditions throughout evolution. In mammals and primates the complexity and sophisticat
Autor:
William C. Eckelman, Carlo Contoreggi, Ying Ma, B. M. Kim, Dale O. Kiesewetter, George P. Chrousos, Kenner C. Rice, Lawrence P. Szajek, Philip W. Gold, Lixin Lang, Elaine M. Jagoda
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 52:394-400
The study of corticotropin-releasing hormone is of significant interest in mental health. We have developed a radiobromination procedure for the preparation of [76Br]BMK-I-152, a high-affinity corticotropin-releasing hormone type 1 receptor antagonis
Autor:
George R. Uhl, Catherine Johnson, Carlo Contoreggi, Tomas Drgon, Judith M. Hess, Daniel Q. Naiman, Qing-Rong Liu, Chuan-Yun Li
Publikováno v:
Annals of the New York Academy of Sciences. 1141:318-381
Genome-wide association (GWA) can elucidate molecular genetic bases for human individual differences in complex phenotypes that include vulnerability to addiction. Here, we review (a) evidence that supports polygenic models with (at least) modest het
Autor:
Svetlana I. Chefer, D. Bruce Vaupel, Alane S. Kimes, Andrew G. Horti, Elliot A. Stein, John A. Matochik, Carlo Contoreggi, Alexey G. Mukhin, Olga A. Pavlova
Publikováno v:
Journal of Nuclear Medicine. 49:1628-1635
Each year, more than 400,000 deaths are related to smoking in the United States (1), and it is estimated that smoking-related illnesses will kill 1 billion people worldwide this century (2). The need for improved treatments for smoking cessation is o
Autor:
Joseph E. Tomaszewski, Carlo Contoreggi, Patrick T. Curry, Elizabeth R. Glaze, David L. McCormick, J. Brooks Harder, Robert L. Morrissey, Kenner C. Rice, Dennis S. Charney, Giovanni Cizza, Karim A. Calis, Thomas L. Horn, Ralph E. Parchment, Philip W. Gold, Paul W. Mellick, William D. Johnson
Publikováno v:
Toxicology. 248:8-17
Non-clinical studies were conducted to evaluate the toxicity of Antalarmin, a corticotropin-releasing hormone type 1 receptor antagonist being developed for therapy of stress-related pathologies. Antalarmin was not genotoxic in bacterial mutagenesis
Autor:
Svetlana I. Chefer, D. Bruce Vaupel, Carlo Contoreggi, Alexey G. Mukhin, John A. Matochik, Alane S. Kimes, Elliot A. Stein
Publikováno v:
NeuroImage. 39:717-727
Quantitative analysis of most positron emission tomography (PET) data requires arterial blood sampling and dynamic scanning when the radioligand is administered as a bolus injection. Less invasive studies can be accomplished if the radioligand is adm
Autor:
Qing-Rong Liu, Oluwatosin O. Fatusin, George R. Uhl, Carlo Contoreggi, Tomas Drgon, Chuan-Yun Li, Kari J. Buck, Catherine Johnson, John C. Crabbe
Publikováno v:
Biochemical Pharmacology. 75:98-111
Family, adoption and twin data each support substantial heritability for addictions. Most of this heritable influence is not substance-specific. The overlapping genetic vulnerability for developing dependence on a variety of addictive substances sugg
Autor:
Carlo Contoreggi
This chapter introduces drug abuse as a widespread public health problem with several medical complications that are infectious due to the transmission of blood-borne, environmental, and respiratory infectious agents. An ongoing opioid epidemic has c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faae1253892c5d443c4daf8d56ddac3
https://doi.org/10.1017/cbo9781139855952.103
https://doi.org/10.1017/cbo9781139855952.103