Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Carlo Cogoni"'
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2969 (2023)
The ribosome is a macromolecular complex composed of RNA and proteins that interact through an integrated and interconnected network to preserve its ancient core activities. In this review, we emphasize the pivotal role played by RNA-binding proteins
Externí odkaz:
https://doaj.org/article/df548ecb0dfa413ba6c2d37b417e04ad
Autor:
Christian Barbato, Paola Frisone, Laura Braccini, Simona D’Aguanno, Luisa Pieroni, Maria Teresa Ciotti, Caterina Catalanotto, Carlo Cogoni, Francesca Ruberti
Publikováno v:
Cells, Vol 11, Iss 6, p 1052 (2022)
RNA-binding proteins (RBPs) play important roles in modulating miRNA-mediated mRNA target repression. Argonaute2 (Ago2) is an essential component of the RNA-induced silencing complex (RISC) that plays a central role in silencing mechanisms via small
Externí odkaz:
https://doaj.org/article/14956a062d714bbfa74ba609d5b200a0
Autor:
Chiara Paolantoni, Simona Ricciardi, Veronica De Paolis, Chinenye Okenwa, Caterina Catalanotto, Maria T. Ciotti, Antonino Cattaneo, Carlo Cogoni, Corinna Giorgi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Activity-regulated cytoskeletal associated protein (Arc) is an immediate-early gene critically involved in synaptic plasticity and memory consolidation. Arc mRNA is rapidly induced by synaptic activation and a portion is locally translated in dendrit
Externí odkaz:
https://doaj.org/article/505d26d55e964976a2da721fa3db14c7
Publikováno v:
Communicative & Integrative Biology, Vol 3, Iss 6, Pp 499-503 (2010)
Amyloid Precursor Protein (APP) and its proteolytic product amyloid beta (Αβ) are critical in the pathogenesis of Alzheimer’s Disease (AD). APP gene duplication and transcriptional upregulation are linked to AD. In addition, normal levels of APP
Externí odkaz:
https://doaj.org/article/c771ee9b20dc4086be6a9588d211f210
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 10, p 1712 (2016)
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a sequence specific manner has had a massive impact on biology. Recent improvements in high throughput sequencing and computational prediction methods have allowed
Externí odkaz:
https://doaj.org/article/bbc0b1862ff14db2a0ae8257f236e111
Autor:
Viviana Caputo, Lorenzo Sinibaldi, Alessia Fiorentino, Chiara Parisi, Caterina Catalanotto, Augusto Pasini, Carlo Cogoni, Antonio Pizzuti
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28656 (2011)
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays an essential role in neuronal development and plasticity. MicroRNA (miRNAs) are small non-coding RNAs of about 22-nucleotides in length regulating gene expression at post-transcrip
Externí odkaz:
https://doaj.org/article/87df736eb9e34b10b9d17193ee6cdcfc
Autor:
Valeria De Arcangelis, Filippo Serra, Carlo Cogoni, Elisabetta Vivarelli, Lucia Monaco, Fabio Naro
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12098 (2010)
In mdx mice, the absence of dystrophin leads to the deficiency of other components of the dystrophin-glycoprotein complex (DAPC), making skeletal muscle fibers more susceptible to necrosis. The mechanisms involved in the disappearance of the DAPC are
Externí odkaz:
https://doaj.org/article/6f01955e5e9d4d18b70f238d32ac5180
Autor:
Giulia Napoli, Noemi Panzironi, Alice Traversa, Caterina Catalanotto, Valentina Pace, Francesco Petrizzelli, Agnese Giovannetti, Sara Lazzari, Carlo Cogoni, Marco Tartaglia, Massimo Carella, Tommaso Mazza, Antonio Pizzuti, Chiara Parisi, Viviana Caputo
The primary cilium is a non-motile sensory organelle that extends from the surface of most vertebrate cells and transduces signals regulating proliferation, differentiation, and migration. Primary cilia dysfunctions have been observed in cancer and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9caaa0d65fbe4dbb77ab331e741b1bc
http://hdl.handle.net/11573/1648078
http://hdl.handle.net/11573/1648078
Autor:
Carlo Cogoni, Michele Zampieri, Carmen Maresca, Rachele Marino, Anna Reale, Caterina Catalanotto, Giuseppe Zardo, Stefania Scalea
Publikováno v:
The FEBS journalReferences. 287(6)
The 'instructive model' of aberrant DNA methylation in human tumors is based on the observation that CpG islands prone to hypermethylation in cancers are embedded in chromatin enriched in H3K27me3 in human embryonic stem cells (hESC). Recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467bab3631bd414df3f972979f4abeb5
https://pubmed.ncbi.nlm.nih.gov/31599112
https://pubmed.ncbi.nlm.nih.gov/31599112
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 14:168-175
Individual microRNAs and/or microRNA signatures were associated with Alzheimer's disease (AD). We report here the recent advances brought to the identification of microRNA changes in AD brain and their biological function in the molecular pathways as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63c28bd3306caa6f877ef431781d363
https://doi.org/10.2174/1871527314666150116123305
https://doi.org/10.2174/1871527314666150116123305