Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Carlo Cenciarelli"'
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the landscape of cancer
Externí odkaz:
https://doaj.org/article/4712aff0cc754bb1b67815785158b41d
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/14d5f0635b514ab3ad02eff286a66e36
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. However, because only
Externí odkaz:
https://doaj.org/article/7cf7e8dac7fc4a2689014226bcb883b4
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Ingrid Cifola, Sara Caratelli, Giuseppe Sconocchia, Igea D’Agnano, Carlo Cenciarelli
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas a
Externí odkaz:
https://doaj.org/article/e4a8f209c4104b86b08c0037bf0c96a9
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Armando Felsani, Giuseppe Tringali, Ingrid Cifola, Giacomo Pozzoli, Carlo Cenciarelli
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem cells (CSC) which confe
Externí odkaz:
https://doaj.org/article/c2c42f4a68994c1d8a64edefd5da1829
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Giacomo Pozzoli, Andrea Morrione, Antonio Giordano, Carlo Cenciarelli
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract The p53 protein is a transcription factor known as the "guardian of the genome" because of its critical function in preserving genomic integrity. The TP53 gene is mutated in approximately half of all human malignancies, including those of th
Externí odkaz:
https://doaj.org/article/bfc96b4559ee4c3da63c2326d55a89a7
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/9ad1f555374c4efaa3dddc3a17334cb8
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Giacomo Pozzoli, Carlo Cenciarelli
Publikováno v:
Cancer Medicine, Vol 10, Iss 15, Pp 5019-5030 (2021)
Abstract Glioblastoma multiforme (GBM) is one of the deadliest brain tumors with an unfavorable prognosis and overall survival of approximately 20 months following diagnosis. The current treatment for GBM includes surgical resections and chemo‐ and
Externí odkaz:
https://doaj.org/article/8f81ddf7588a4518bd8b88a03be920b1
Autor:
Hany E. Marei, Carlo Cenciarelli
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 627 (2023)
Given that CAR-T cell therapy is effective in CD19-positive blood malignancies, it offers great hope for a variety of aggressive tumors that have thus far shown very little response to available therapies [...]
Externí odkaz:
https://doaj.org/article/6a922f30344048d0a6df31966673c3cb
Autor:
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Giacomo Pozzoli, Carlo Cenciarelli
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102552- (2021)
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense mutation is associated wit
Externí odkaz:
https://doaj.org/article/e99643c49aef47e1b09d079eb4502d3c