Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carlo Bigiotti"'
Autor:
Elisa Bianconi, Anna Gidari, Maria Souma, Samuele Sabbatini, Deborah Grifagni, Carlo Bigiotti, Elisabetta Schiaroli, Lucia Comez, Alessandro Paciaroni, Francesca Cantini, Daniela Francisci, Antonio Macchiarulo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Non-structural protein 5 (Nsp5) is a cysteine protease that plays a key role in SARS-CoV-2 replication, suppressing host protein synthesis and promoting immune evasion. The investigation of natural products as a potential strategy for Nsp5 inhibition
Externí odkaz:
https://doaj.org/article/9cb6c05eee4a4813a77d76c7d39b0a1b
Autor:
Elisa Bianconi, Alessandra Riccio, Luana Ruta, Carlo Bigiotti, Andrea Carotti, Sonia Moretti, Bruno Cerra, Antimo Gioiello, Simone Ferlin, Efisio Puxeddu, Antonio Macchiarulo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5535 (2023)
PD-1/PD-L1 protein complex is attracting a great deal of interest as a drug target for the design of immune therapies able to block its assembly. Although some biologic drugs have entered clinical use, their poor response rate in patients are demandi
Externí odkaz:
https://doaj.org/article/390a90695a4140999d9d93d54335d7ae
Autor:
Andrea Mammoli, Elisa Bianconi, Luana Ruta, Alessandra Riccio, Carlo Bigiotti, Maria Souma, Andrea Carotti, Sofia Rossini, Chiara Suvieri, Maria Teresa Pallotta, Ursula Grohmann, Emidio Camaioni, Antonio Macchiarulo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3981 (2022)
Over the last two decades, indoleamine 2,3-dioxygenase 1 (IDO1) has attracted wide interest as a key player in immune regulation, fostering the design and development of small molecule inhibitors to restore immune response in tumor immunity. In this
Externí odkaz:
https://doaj.org/article/1e036dd7f2e548679a5e944b0d5bc595