Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Carlo Bertucci"'
Autor:
Laura Verardi, Jessica Fiori, Vincenza Andrisano, Alessandra Locatelli, Rita Morigi, Marina Naldi, Carlo Bertucci, Elena Strocchi, Carla Boga, Gabriele Micheletti, Natalia Calonghi
Publikováno v:
Molecules, Vol 25, Iss 19, p 4438 (2020)
Ovarian cancer remains the leading cause of mortality among gynecological tumors. Estrogen receptor beta (ERβ) expression has been suggested to act as a tumor suppressor in epithelial ovarian cancer by reducing both tumor growth and metastasis. ERβ
Externí odkaz:
https://doaj.org/article/be420aa9870045ca93001236548acb64
Autor:
Priscila Freitas-Lima, Flavia Isaura Santi Ferreira, Carlo Bertucci, Veriano Alexandre Júnior, Sônia Aparecida Carvalho Dreossi, Leonardo Regis Leira Pereira, Américo Ceiki Sakamoto, Regina Helena Costa Queiroz
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 2, Pp 393-401 (2015)
Levetiracetam (LEV), an antiepileptic drug (AED) with favorable pharmacokinetic profile, is increasingly being used in clinical practice, although information on its metabolism and disposition are still being generated. Therefore a simple, robust and
Externí odkaz:
https://doaj.org/article/cf8c7923f0804e0a9833dd41df7b4d0a
Autor:
Natalia Calonghi, Concettina Cappadone, Eleonora Pagnotta, Carla Boga, Carlo Bertucci, Jessica Fiori, Gianluca Tasco, Rita Casadio, Lanfranco Masotti
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1596-1603 (2005)
Recent studies have shown that an endogenous lipoperoxidation product, 9-hydroxystearic acid (9-HSA), acts in colon carcinoma cells (HT29) as a growth inhibitor by inducing p21WAF1 in an immediate-early, p53-independent manner and that p21WAF1 is req
Externí odkaz:
https://doaj.org/article/0c4355253a7c4de19b1a28245b04f6e3
Autor:
Giovanni Scambia, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Daniela Gallo, Simona Mozzetti, Carlo Bertucci, Samanta Cimitan, Silvia Bartollino, Giuseppina Raspaglio, Lucia Cicchillitti, Cristiano Ferlini
Supplementary Tables 1-3 from Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2143fb090015dc7bab071b0ec04e3a0d
https://doi.org/10.1158/0008-5472.22378748
https://doi.org/10.1158/0008-5472.22378748
Autor:
Giovanni Scambia, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Daniela Gallo, Simona Mozzetti, Carlo Bertucci, Samanta Cimitan, Silvia Bartollino, Giuseppina Raspaglio, Lucia Cicchillitti, Cristiano Ferlini
We reported previously that Bcl-2 is paradoxically down-regulated in paclitaxel-resistant cancer cells. We reveal here that paclitaxel directly targets Bcl-2 in the loop domain, thereby facilitating the initiation of apoptosis. Molecular modeling rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ead0c99825c487f3659a76bd107582
https://doi.org/10.1158/0008-5472.c.6499004
https://doi.org/10.1158/0008-5472.c.6499004
Autor:
Alberto Del Rio, Edoardo Fabini, Marina Naldi, Carlo Bertucci, Filip Mihalic, Vladimir O. Talibov, U. Helena Danielson, Manuela Bartolini
Publikováno v:
Biochemistry. 58:3634-3645
SET and MYND domain-containing protein 3 (SMYD3) is a lysine methyltransferase that plays a central role in a variety of cancer diseases, exerting its pro-oncogenic activity by methylation of key proteins, of both nuclear and cytoplasmic nature. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36809df1ea32a60bdc83d1e0b11b5d5
https://doi.org/10.1021/acs.biochem.9b00420
https://doi.org/10.1021/acs.biochem.9b00420
Autor:
Marina Naldi, Daniele Tedesco, Maurizio Baldassarre, Manuela Bartolini, Anna Tramarin, Carlo Bertucci
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 162:171-178
The ADMET profile of drugs is strongly affected by human serum albumin (HSA), due to its leading role as carrier of poorly soluble compounds in plasma; a critical assessment of the binding capacity of HSA and the evaluation of binding competition bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9704308fa05013a0d6785aa8684095
https://doi.org/10.1016/j.jpba.2018.09.022
https://doi.org/10.1016/j.jpba.2018.09.022
Autor:
Carla Boga, Marina Naldi, Jessica Fiori, Vincenza Andrisano, Laura Verardi, Elena Strocchi, Carlo Bertucci, Natalia Calonghi, Rita Morigi, Gabriele Micheletti, Alessandra Locatelli
Publikováno v:
Molecules, Vol 25, Iss 4438, p 4438 (2020)
Molecules
Volume 25
Issue 19
Molecules
Volume 25
Issue 19
Ovarian cancer remains the leading cause of mortality among gynecological tumors. Estrogen receptor beta (ER&beta
) expression has been suggested to act as a tumor suppressor in epithelial ovarian cancer by reducing both tumor growth and metasta
) expression has been suggested to act as a tumor suppressor in epithelial ovarian cancer by reducing both tumor growth and metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ba9b2be4ed9fe774620e9362684e12
http://hdl.handle.net/11585/774423
http://hdl.handle.net/11585/774423
Autor:
Vakhtang Barbakadze, Daniele Tedesco, Bezhan Chankvetadze, Carlo Bertucci, Edoardo Fabini, Riccardo Zanasi, Maia Merlani
Publikováno v:
Chirality. 27:914-918
Caffeic acid-derived polyethers are a class of natural products isolated from the root extracts of comfrey and bugloss, which are endowed with intriguing pharmacological properties as anticancer agents. The synthesis of new polyether derivatives is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996db697e0da4454d629c440a268f61d
https://doi.org/10.1002/chir.22539
https://doi.org/10.1002/chir.22539