Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Carlo Amadeo Alonzo"'
Autor:
Disha Sood, Zhiyi Liu, Emily Stuntz, David L. Kaplan, Irene Georgakoudi, Volha Liaudanskaya, Dimitra Pouli, Carlo Amadeo Alonzo, Kyle P. Quinn, Yusi Gong
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
As neurodegenerative conditions are increasingly linked to mitochondrial dysfunction, methods for studying brain cell metabolism at high spatial resolution are needed to elucidate neurodegeneration mechanisms. Two-photon excited fluorescence (TPEF) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726bb01e2556b1991d79e8231a98aa5c
https://doaj.org/article/892df3322ed645709c32c8c32e640f6a
https://doaj.org/article/892df3322ed645709c32c8c32e640f6a
Autor:
Zhiyi Liu, Carlo Amadeo Alonzo, Carlos Sonnenschein, Kyle P. Quinn, Emily Stuntz, Ana M. Soto, Irene Georgakoudi, Yang Zhang, Lucia Speroni, Dimitra Pouli
Hormones play an important role in normal and diseased breast tissue development. However, they can also disrupt cell-matrix interactions and their role in extracellular matrix reorganization during epithelial morphogenesis remains poorly understood,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993bb3ff918312167493ab62b4035e39
https://europepmc.org/articles/PMC6176712/
https://europepmc.org/articles/PMC6176712/
Autor:
Antonio Varone, Kyle P. Quinn, Karl Münger, Irene Georgakoudi, Zhiyi Liu, Sevasti Karaliota, Carlo Amadeo Alonzo, Katia Karalis, Dimitra Pouli
Publikováno v:
Science Advances
Two-photon imaging provides noninvasive, label-free, quantitative assays of metabolic changes at the single-cell or tissue level.
Monitoring subcellular functional and structural changes associated with metabolism is essential for understanding
Monitoring subcellular functional and structural changes associated with metabolism is essential for understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faf63f63886cc8af2c1a1f2e417a587
http://europepmc.org/articles/PMC5846284
http://europepmc.org/articles/PMC5846284
Autor:
Sevasti Karaliota, Zhiyi Liu, Katia Karalis, Karl Münger, Antonio Varone, Kyle P. Quinn, Irene Georgakoudi, Carlo Amadeo Alonzo, Dimitra Pouli
Publikováno v:
Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS).
We report on the combined use of endogenous two-photon intensity and lifetime based fluorescence measurements to identify changes in specific metabolic pathways. Such functional insights can improve understanding of disease development and drug effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d6b1740094794b87d0a8489e9678eb
https://doi.org/10.1364/translational.2018.jth1a.1
https://doi.org/10.1364/translational.2018.jth1a.1
Autor:
David L. Kaplan, Carlo Amadeo Alonzo, Adam Zieba, Irene Georgakoudi, Francis E. Borowsky, Rosalyn D. Abbott
Obesity is a risk factor for a myriad of diseases including diabetes, cardiovascular dysfunction, cirrhosis and cancer and there is a need for new systems to study how excess adipose tissue relates to the onset of disease processes. This study provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676e106b50fee4ff0a533d88f2d09060
https://europepmc.org/articles/PMC5839961/
https://europepmc.org/articles/PMC5839961/
Publikováno v:
Optics in the Life Sciences Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1c0bf1c84c248d2122f6e9fe17daa4
https://doi.org/10.1364/omp.2017.oms2d.2
https://doi.org/10.1364/omp.2017.oms2d.2
Publikováno v:
International Conference on Photonics and Imaging in Biology and Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71005c3289289c212fd034968c2f036a
https://doi.org/10.1364/pibm.2017.w2a.2
https://doi.org/10.1364/pibm.2017.w2a.2
Autor:
Kyongbum Lee, Carlo Amadeo Alonzo, Dimitra Pouli, Joanna Xylas, Antonio Varone, Kyle P. Quinn, Gautham V. Sridharan, Irene Georgakoudi, Karl Münger, Margaret E. McLaughlin-Drubin
Publikováno v:
Cancer Research. 74:3067-3075
Alterations in the balance between different metabolic pathways used to meet cellular bioenergetic and biosynthetic demands are considered hallmarks of cancer. Optical imaging relying on endogenous fluorescence has been used as a noninvasive approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed07319834dc092c9fd864be6b0cacc
https://doi.org/10.1158/0008-5472.can-13-2713
https://doi.org/10.1158/0008-5472.can-13-2713
Publikováno v:
Biomaterials. 35:3794-3802
The goal of this study was to explore quantitative assessments of mineralized silk protein biomaterial films by co-cultures of human mesenchymal stem cell-derived osteoblasts and human acute monocytic leukemia cell line-derived osteoclasts during lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198c4bd5a2c4b58f19536ee228383526
https://doi.org/10.1016/j.biomaterials.2014.01.034
https://doi.org/10.1016/j.biomaterials.2014.01.034
Autor:
Lisa M. Arendt, Disha Sood, Kyle P. Quinn, Dimitra Pouli, Carlo Amadeo Alonzo, Aswin Sundarakrishnan, Charlotte Kuperwasser, Zhiyi Liu, Li Zeng, Irene Georgakoudi, Carrie K. Hui Mingalone, Thomas Schnelldorfer, David L. Kaplan
Fiber-like structures are prevalent in biological tissues, yet quantitative approaches to assess their three-dimensional (3D) organization are lacking. We develop 3D directional variance, as a quantitative biomarker of truly 3D fibrillar organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbce93cbaf278864ec739be1ffe152b2
https://europepmc.org/articles/PMC5210183/
https://europepmc.org/articles/PMC5210183/